Results 241 to 250 of about 1,133,037 (342)

Enhancing Cancer Vaccine Efficacy: Backbone Modification with β‑Amino Acids Alters the Stability and Immunogenicity of MUC1-Derived Glycopeptide Formulations

JACS Au
Ruslan Gibadullin, Óscar Suárez, Foivos S. Lazaris, Naiara Gutiez, Estibaliz Atondo, Sarai Araujo-Aris, Ander Eguskiza, Jiani Niu, Ariel J. Kuhn, Ana S. Grosso, Héctor Rodriguez, Fayna García-Martín, Filipa Marcelo, Tanausú Santos, Alberto Avenoza, Jesús H. Busto, Jesús M. Peregrina, Samuel H. Gellman, Juan Anguita, Roberto Fiammengo, Francisco Corzana   +20 more
doaj   +1 more source

Macrophages: their role in immunity and their relationship with fatty acids in health and disease. [PDF]

Front Immunol
Rueda-Munguía M, Luévano-Martínez LA, García-Rivas G, Castillo EC, Lozano O.   +4 more
europepmc   +1 more source

Inhaled GM-CSF in neonatal mice provides durable protection against bacterial pneumonia [PDF]

, 2019
Morley, S. Celeste, Ramani, Rashmi, Szasz, Taylor P, Todd, Elizabeth M   +3 more
core   +2 more sources

Engineering macrophages to eat cancer: from “marker of self” CD47 and phagocytosis to differentiation [PDF]

, 2017
Cory Alvey, Dennis E. Discher
openalex   +1 more source

Cortical Response to Acute Implantation of the Utah Optrode Array in Macaque Cortex

Advanced Healthcare Materials, EarlyView.
Delivering light deep into the brain over a large volume while causing minimal tissue damage is a major challenge for non‐human primate optogenetics. This study evaluates Utah Optrode Array designs in vivo, revealing how changes in shank geometry, surface texture, and insertion parameters minimize acute damage—offering a path toward high‐precision ...
Adrián Villamarin‐Ortiz, Christopher F. Reiche, Frederick Federer, Andrew M. Clark, John D. Rolston, Cristina Soto‐Sánchez, Eduardo Fernandez, Steve Blair, Alessandra Angelucci   +8 more
wiley   +1 more source

Knockdown of LncRNA CCAT1 Attenuates ox-LDL-Induced Inflammation in THP1-Derived Macrophages via the miR-296-3p/FOSL1 Axis. [PDF]

Cardiovasc Ther
Zhang H, Liu F, Miao G, Wang Y, Zhang L, Yang C, Huang K, Guo F, An J, He B, Ye J.   +10 more
europepmc   +1 more source

Cell Calcification Models and Their Implications for Medicine and Biomaterial Research

Advanced Healthcare Materials, EarlyView.
Calcification, is the process by which the tissues containing minerals are formed, occurring during normal physiological processes, or in pathological conditions. Here, it is aimed to give a comprehensive overview of the range of cell models available, and the approaches taken by these models, highlighting when and how methodological divergences arise,
Luke Hunter, Caterina Vanelli Coralli, Robert Dzhanaev, Aaron Morgan, Willi Jahnen‐Dechent, Sergio Bertazzo   +5 more
wiley   +1 more source

CD44v5 enhances the IL-4/IL-4Rα/STAT6/SAM68 aix inducing M2 polarization and promoting triple-negative breast cancer progression. [PDF]

Cancer Biol Ther
Ji Z, Wang L, Bao X, Dai Y, Jiang M, Ma H, Li N, Yang C.   +7 more
europepmc   +1 more source

A Novel Core–Shell Hydrogel 3D Model for Studying Macrophage Mechanosensing and Foreign Body Giant Cell Formation

Advanced Healthcare Materials, EarlyView.
The foreign body response (FBR) to biomaterials is primarily driven by macrophages, which often fuse into destructive foreign body giant cells (FBGCs). To address the limited understanding of FBGC formation, a novel microscale core–shell hydrogel 3D model is developed using heterogeneous alginate‐collagen microcapsules with varying stiffness, offering ...
Manisha Mahanty, Wenquan Ou, Xiaoping Zhu, Jonathan S Bromberg, Xiaoming He, Shaik O. Rahaman   +5 more
wiley   +1 more source

Optimization of the Nonclinical Biological Evaluation of Medical Devices Using Toxicologic Pathology Best Practices

Advanced Healthcare Materials, EarlyView.
Nonclinical evaluation of biological responses to implanted medical devices and combination products in animals is required to predict possible outcomes and risks in patients. This paper describes globally accepted pathology “best practices” that 1) effectively address ISO standards and current regulatory guidance for medical device development and 2 ...
Kathleen A. Funk, JoAnn C. L. Schuh, Brad Bolon, Valerie S. Thomas, Jeffrey I. Everitt, Abraham Nyska, Jaime Paulin   +6 more
wiley   +1 more source