Designing for Degradation: Transient Devices Enabled by (Nano)Cellulose
Recent progress in transient devices enabled by (nano)cellulosic materials is reviewed. Transiency mechanisms, advantages of nanocelluloses, and a suite of applications are discussed. A circular thinking approach coupled with life cycle assessment is applied to critically revisit the potential, advantages, and challenges of nanocellulose‐enabled ...
Lucas J. Andrew+2 more
wiley +1 more source
Molecular features and diagnostic modeling of synovium- and IPFP-derived OA macrophages in the inflammatory microenvironment via scRNA-seq and machine learning. [PDF]
Lin C, Wan Y, Xu Y, Zou Q, Li X.
europepmc +1 more source
Pulmonary Alveolar Macrophage DEFENDER AGAINST BACTERIAL INFECTION OF THE LUNG [PDF]
Elliot Goldstein+2 more
openalex +1 more source
Convergence drawing is used to create flexible, microscale, multifunctional fiber‐based neural probes. Optimized materials selection enables individual devices to perform neural recording, electrical stimulation, optogenetics, fiber photometry, fluid delivery, and voltammetric neurotransmitter detection in rodents.
Nicolette Driscoll+16 more
wiley +1 more source
Transcriptomic characterization of human pancreatic CD206- and CD206 + macrophages. [PDF]
Jonsson A, Korsgren O, Hedin A.
europepmc +1 more source
The Rôle of the Large Peritoneal Macrophage in Tumour Homograft Rejection
F Hartveit
openalex +2 more sources
Engineering CAR‐T Therapeutics for Enhanced Solid Tumor Targeting
CART cell therapy has proven effective for blood cancers but struggles with solid tumors due to diverse antigens and complex environments. Recent efforts focus on improving CAR design and validation platforms. Advances in protein engineering, machine learning, and organoid systems aim to enhance CAR‐T therapy against solid tumors.
Danqing Zhu+4 more
wiley +1 more source
YTHDC2 manipulates anti-tumoral macrophage polarization and predicts favorable outcomes in triple negative breast cancer. [PDF]
Jin H+7 more
europepmc +1 more source
Cardiac Organoid Model Inspired Micro‐Robot Smart Patch to Treat Myocardial Infarction
The heart organoid model exhibits the acidic microenvironment characteristic of myocardial infarction, which emerges as a pivotal force propelling the movement of micro‐robots. These micro‐robots, administered through microneedles, can penetrate deep into the tissue, effectively delivering therapeutic payloads to facilitate heart repair.
Fangfang Wang+12 more
wiley +1 more source
Protein‐Like Polymers Targeting Keap1/Nrf2 as Therapeutics for Myocardial Infarction
We describe a Keap1 targeting protein‐like polymer (PLP) which activates Nrf2, an important cytoprotective transcription factor for relieving myocardial infarction‐induced oxidative stress. This PLP increases cell survival in vitro in multiple relevant cardiac cell types and elicits pro‐reparative responses, improving cardiac function in a preclinical ...
Joshua M. Mesfin+17 more
wiley +1 more source