Results 311 to 320 of about 1,540,630 (392)
Early bone regeneration is challenged by poor osteogenic microenvironments. We developed a novel guided bone regeneration (GBR) membrane: a plasma‐treated polycaprolactone (PT‐PCL) electrospun nanofiber functionalized with ultrasound sequentially extruded stromal vascular fraction chimeric vesicles (USE‐SCNVs). USE‐SCNVs require less equipment, enhance
Yufan Zhang+13 more
wiley +1 more source
Physical cues in biomaterials modulate macrophage polarization for bone regeneration: a review. [PDF]
Yang T, Fang Z, Zhang J, Zheng S.
europepmc +1 more source
Differential Phase Contrast Imaging to Predict MSC Immune Function
This work employs quantitative differential phase contrast (qDPC) imaging technique to non‐invasively extract morphological features from live Mesenchymal Stromal Cells (MSCs) for single cell prediction on cell immunomodulatory capacity. This work establishes a foundation for scalable, non‐destructive monitoring of MSCs immunomodulatory capacity ...
Kejie Rui+5 more
wiley +1 more source
Inhibition of inner ear macrophage phagocytosis alleviates cisplatin-induced ototoxicity. [PDF]
Zhang J, Zhang W, Huang X, Li M, Yang H.
europepmc +1 more source
This study presents alkylated nitrobenzoselenadiazole (NBSD) photosensitizers that self‐assemble into programmable aggregates, enabling photo‐triggered pyroptosis and enhanced ROS generation. The lead compound, NBSD‐NOc, exhibits superior photodynamic activity, high cellular uptake, and implantable gel compatibility with pH‐responsive release.
Jong Min An+8 more
wiley +1 more source
Targeting STING to disrupt macrophage-mediated adhesion in encapsulating peritoneal sclerosis. [PDF]
Sun J+14 more
europepmc +1 more source
Impact of Nanoparticle Stiffness on Endosomal Escape and Signaling Pathways in Cytosolic Delivery
Nanoparticle (NP) stiffness affects cellular uptake, but its impact on intracellular distribution remains unclear. This study synthesizes silica nanocapsules with varying stiffness, inspired by viral mechanisms, and applies assays to measure cellular uptake and escape efficiency.
Yali Zhang+6 more
wiley +1 more source
Macrophages: Subtypes, Distribution, Polarization, Immunomodulatory Functions, and Therapeutics. [PDF]
Peng M+10 more
europepmc +1 more source
Multiscale Profiling of Nanoscale Metal‐Organic Framework Biocompatibility and Immune Interactions
A multi‐scale, hierarchical ‘Safety‐by‐Design’ pipeline combining machine learning, ex vivo human blood assays, and in vivo models enables the systematic immunotoxicity and biocompatibility profiling of nanoscale metal‐organic frameworks, accelerating their safe clinical translation. Abstract The clinical translation of metal‐organic frameworks (MOFs) –
Yunhui Zhuang+12 more
wiley +1 more source