Results 311 to 320 of about 1,133,037 (342)
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Macrophages in cholangiopathies
Current Opinion in Gastroenterology, 2021Purpose of review Cholangiopathies are a heterogeneous class of liver diseases where cholangiocytes are the main targets of liver injury. Although available and emerging therapies mainly target bile acids (ursodeoxycholic acid/UDCA, 24-Norursodeoxycholic acid/norUDCA) and related signaling pathways (obeticholic acid, fibrates ...
Alix, Bruneau +2 more
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Cellular Immunology, 1983
It is a pleasure and a privilege to be here today to honor Lewis Thomas. As I look out on this distinguished audience and see so many good friends, it brings on an attack of nostalgia for the early sixties on the sixth floor of Building D in Bellevue. Those years with Jerry and Lew were some of the most exciting and satisfying of my career. The sixties
J R, David +4 more
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It is a pleasure and a privilege to be here today to honor Lewis Thomas. As I look out on this distinguished audience and see so many good friends, it brings on an attack of nostalgia for the early sixties on the sixth floor of Building D in Bellevue. Those years with Jerry and Lew were some of the most exciting and satisfying of my career. The sixties
J R, David +4 more
openaire +2 more sources
Reproductive Sciences, 2008
During implantation, apoptosis is critical for the appropriate tissue remodeling of the maternal decidua and invasion of the developing embryo. Yet the regulation of apoptosis is also imperative for a successful pregnancy. The quick and effective removal of apoptotic cells by tissue macrophages represents an essential process, which prevents the ...
Gil, Mor, Kaori, Koga
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During implantation, apoptosis is critical for the appropriate tissue remodeling of the maternal decidua and invasion of the developing embryo. Yet the regulation of apoptosis is also imperative for a successful pregnancy. The quick and effective removal of apoptotic cells by tissue macrophages represents an essential process, which prevents the ...
Gil, Mor, Kaori, Koga
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Frontiers in Bioscience, 2008
Macrophages are ubiquitous cells physiologically involved in a variety of processes including pathogen destruction, inflammation, tissue repair and remodeling. They have a highly plastic phenotype and their functional polarization is determined by cytokines and factors found within local microenvironments.
Alessandra, Nardin +1 more
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Macrophages are ubiquitous cells physiologically involved in a variety of processes including pathogen destruction, inflammation, tissue repair and remodeling. They have a highly plastic phenotype and their functional polarization is determined by cytokines and factors found within local microenvironments.
Alessandra, Nardin +1 more
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2011
Macrophages are a diverse phenotype of professional phagocytic cells derived from bone-marrow precursors and parent monocytes in the peripheral blood. They are essential for the maintenance and defence of host tissues, doing so by sensing and engulfing particulate matter and, when necessary, initiating a pro-inflammatory response.
Chris P, Verschoor +2 more
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Macrophages are a diverse phenotype of professional phagocytic cells derived from bone-marrow precursors and parent monocytes in the peripheral blood. They are essential for the maintenance and defence of host tissues, doing so by sensing and engulfing particulate matter and, when necessary, initiating a pro-inflammatory response.
Chris P, Verschoor +2 more
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BioEssays, 1995
AbstractThe macrophage plays an important role in host development and physiology, and in pathogenesis of many infectious, immunologic and degenerative disease processes. It displays marked heterogeneity of phenotype in different tissues, reflecting local interactions with other cell types, and contributes to host homeostasis through a varied ...
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AbstractThe macrophage plays an important role in host development and physiology, and in pathogenesis of many infectious, immunologic and degenerative disease processes. It displays marked heterogeneity of phenotype in different tissues, reflecting local interactions with other cell types, and contributes to host homeostasis through a varied ...
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Cancer and Metastasis Reviews, 1990
The uncontrolled growth of metastases resistant to conventional therapeutic modalities is a major cause of death from cancer. Data from our laboratory and others indicate that metastases arise from the nonrandom spread of specialized malignant cells that preexist within a primary neoplasm.
P W, Whitworth +4 more
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The uncontrolled growth of metastases resistant to conventional therapeutic modalities is a major cause of death from cancer. Data from our laboratory and others indicate that metastases arise from the nonrandom spread of specialized malignant cells that preexist within a primary neoplasm.
P W, Whitworth +4 more
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Atherosclerosis and Macrophages
Acta Pathologica Japonica, 1989Atherosclerosis is undoubtedly a disease of many facets and in this review we have merely touched one angle of this issue. The best‐established cause of the disease is hyper‐cholesterolemia. Since the important role of macrophages in lipoprotein metabolism has been confirmed, current interest is focused on the role of macrophages in atherosclerosis ...
T, Watanabe +3 more
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Annual Review of Physiology, 2017
Macrophage polarization refers to how macrophages have been activated at a given point in space and time. Polarization is not fixed, as macrophages are sufficiently plastic to integrate multiple signals, such as those from microbes, damaged tissues, and the normal tissue environment.
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Macrophage polarization refers to how macrophages have been activated at a given point in space and time. Polarization is not fixed, as macrophages are sufficiently plastic to integrate multiple signals, such as those from microbes, damaged tissues, and the normal tissue environment.
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Cellular Immunology, 2018
Alveolar macrophages are the most abundant innate immune cells in the distal lung parenchyma, located on the luminal surface of the alveolar space. They are the first to encounter incoming pathogens and pollutants and to help orchestrate the initiation and resolution of the immune response in the lung.
Nikita, Joshi +2 more
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Alveolar macrophages are the most abundant innate immune cells in the distal lung parenchyma, located on the luminal surface of the alveolar space. They are the first to encounter incoming pathogens and pollutants and to help orchestrate the initiation and resolution of the immune response in the lung.
Nikita, Joshi +2 more
openaire +2 more sources