Results 311 to 320 of about 1,025,840 (365)

Synthetic Mucus Biomaterials Synergize with Antibiofilm Agents to Combat Pseudomonas aeruginosa Biofilms

Advanced Therapeutics, EarlyView.
Mucus‐inspired biomaterials are developed that inhibit biofilm formation and enhance dispersal when combined with DNase and/or α‐amylase. The combination led to up to 2‐log reductions in biofilm viability, offering a promising alternative to traditional antibiotics for treating persistent, antibiotic‐resistant infections.
Sydney Yang, Allison Boboltz, Alexa Stern, Vaidehi Rathi, Gregg Duncan   +4 more
wiley   +1 more source

Lung Tissue Extracellular Vesicles-Mediated Delivery of miR-128-3p as a Novel Mechanism of Acute Lung Inflammation. [PDF]

Int J Nanomedicine
Deng W, Zhu X, Li H, Hu P, Qian K, Liu F.   +5 more
europepmc   +1 more source

Bee Better: The Role of Honey in Modern Wound Care

Advanced Therapeutics, EarlyView.
The use of honey as a wound care agent is controversial but paradoxically increasingly popular. Honey possesses relevant antimicrobial properties and can modulate the immune system. The wound healing properties of honey likely depend on its composition and varies across wound types.
Léo‐Paul Tricou, Natalie Guirguis, Sarah Djebbar, Benjamin R. Freedman, Simon Matoori   +4 more
wiley   +1 more source

Role and mechanism of mitochondrial dysfunction‑related gene biomarkers in the progression of type 2 diabetes mellitus. [PDF]

Mol Med Rep
Liu M, Qiao H.
europepmc   +1 more source

Hydroxyapatite Binding Peptide Lipid Nanoparticles for Biomimetic mRNA Delivery to Bone

Advanced Therapeutics, EarlyView.
Targeted delivery of therapeutic mRNA to peripheral tissues, including bone, is currently challenging. In the current work, a hydroxyapatite binding peptide (HABP) is conjugated to mRNA lipid nanoparticles (LNPs). HABP‐LNPs delivered systemically are demonstrated to reduce transfection in the liver and improve transfection in the femurs of mice ...
Joshua A. Choe, Jena E. Moseman, Jamie M. Jones, Jacobus C. Burger, Ashley M. Weichmann, Douglas G. McNeel, William L. Murphy   +6 more
wiley   +1 more source

USP5 motivates immunosuppressive microenvironment in multiple myeloma by activating STAT2-PFKFB4-mediated glycolysis. [PDF]

Cancer Immunol Immunother
Long S, Ding T, Zheng Y, Shao J, Liu Y, Wang Q.   +5 more
europepmc   +1 more source

Insights on Advances in 3D Bioprinting for Peripheral Nerve Regeneration

Advanced Therapeutics, EarlyView.
Peripheral nerve injury is a common condition due to trauma that significantly impacts the life of the affected individual. This review explores the anatomy, classification, and pathophysiology of peripheral nerve injuries. It also discusses various types of nerve conduits and presents a detailed review of 3D bioprinted nerve conduits used in both in ...
Nasera Rizwana, Samartha M C, Ashwath Acharya, Goutam Thakur, Manasa Nune, Vipul Agarwal   +5 more
wiley   +1 more source

Bibliometric and visual analysis in the field of macrophages in Traditional Chinese Medicine from 2003 to 2023. [PDF]

Front Immunol
Zhang W, Zhao K, Ma R, Ma M, Du Y, Fang P.   +5 more
europepmc   +1 more source

On the Relentless Pursuit of an Oral Insulin Delivery System: How Far is Too Far?

Advanced Therapeutics, EarlyView.
Injectable insulin preparations have far outpaced oral ones by virtue of adequate bioavailability and are driven by innovations, including insulin pumps, real‐time blood glucose monitoring, and artificial intelligence. In contrast, oral insulin delivery systems, including nanomedicines, continue to struggle and lag due to varied reasons.
Sourav Bhattacharjee
wiley   +1 more source

PRMT5 deficiency in myeloid cells reprograms macrophages to enhance antitumor immunity and synergizes with anti-PD-L1 therapy. [PDF]

J Immunother Cancer
Chen S, Chen Z, Zhou B, Chen Y, Huang Y, Cao J, Shen L, Zheng Y.   +7 more
europepmc   +1 more source