Results 321 to 330 of about 1,025,840 (365)

Accelerated Bone Healing via Electrical Stimulation

Advanced Science, EarlyView.
Electrical stimulation significantly impacts bone healing by enhancing osteoblast proliferation, differentiation, and vascularization through calmodulin/calcineurin/NFAT signaling. It also boosts macrophage function and cell migration, presenting a comprehensive approach to accelerating bone repair.
Jianfeng Sun, Wenqing Xie, Yuxiang Wu, Zhou Li, Yusheng Li   +4 more
wiley   +1 more source

The CD163 + tissue-infiltrating macrophages regulate ferroptosis in thyroid-associated ophthalmopathy orbital fibroblasts via the TGF-β/Smad2/3 signaling pathway. [PDF]

J Transl Med
Li X, Wang S, Cao H, Xu S, Xiong C, Yu J, Chen Y, Ren Z, Li M, Hu Y, Gan P, Xu Q, Wang Y, Liao H.   +13 more
europepmc   +1 more source

Metabolic‐Immune Suppression Mediated by the SIRT1‐CX3CL1 Axis Induces Functional Enhancement of Regulatory T Cells in Colorectal Carcinoma

Advanced Science, EarlyView.
This study discovers that SIRT1, a hub gene involved in glucolipid metabolic conversion in colorectal carcinoma (CRC), stimulates CX3CL1 secretion in CRC cells by activating FOXO1. The CX3CL1‐CX3CR1 signaling promotes the differentiation of TCF7+ regulatory T cells (Tregs) into an enhanced immunosuppressive TNFRSF9+ Treg phenotype.
Ruiyang Zi, Xiang Zhao, Limei Liu, Yijie Wang, Rui Zhang, Zhiheng Bian, Haoran Jiang, Taorui Liu, Yixin Sun, Han Peng, Xuesong Wang, Fanghao Lu, Chao Zhang, Fan Zhang, Qing Qin, Houjie Liang, Jianjun Li, Zhihao Wei, Yan Dong   +18 more
wiley   +1 more source

Crosstalk between macrophages and adjacent cells in AKI to CKD transition. [PDF]

Ren Fail
Lin Y, Yang Q, Zeng R.
europepmc   +1 more source

CCL20/CXCL5 Drives Crosstalk Between Anaplastic Thyroid Cancer Stem Cells and Tumor‐Associated Macrophages to Promote Tumor Progression

Advanced Science, EarlyView.
This study elucidates the crosstalk between tumor‐associated macrophages (TAMs) and anaplastic thyroid cancer stem cells (ATCSCs). The findings reveal that CCL20 from THP‐1‐M2 activates the IRAK‐1/NF‐κB1/2 pathway in ATCSCs, thereby enhancing CXCL5 secretion.
Qi Liu, Yan Wang, Mingyuan Song, Jiapeng Huang, Jinyuan Shi, Wei Sun, Xiaoyu Ji, Yuang Chang, Bing Ma, Ping Zhang, Yuanyuan Yan, Hao Zhang   +11 more
wiley   +1 more source

Mdivi-1 Attenuates Sepsis-Associated Acute Lung Injury by Inhibiting M1 Alveolar Macrophage Polarization and Pyroptosis. [PDF]

Mediators Inflamm
Zhang X, Fan H, Su L, Wang Y, Chen G.
europepmc   +1 more source

Spatiotemporal Transcriptomic Profiling Reveals the Dynamic Immunological Landscape of Alveolar Echinococcosis

Advanced Science, EarlyView.
An unprecedented high‐resolution spatial atlas of the E. multilocularis infection foci is obtained, revealing the dynamic functions of neutrophils, Spp1+ macrophages, and fibroblasts during disease progression. The transition of parasite control strategy from “active killing” to “negative segregation” by the host may provide instructive insights into ...
Zhihua Ou, Li Li, Peidi Ren, Ting‐Ting Zhou, Fan He, Jialing Chen, Huimin Cai, Xiumin Han, Yao‐Dong Wu, Jiandong Li, Xiu‐Rong Li, Qiming Tan, Wenhui Li, Qi Chen, Nian‐Zhang Zhang, Xiuju He, Wei‐Gang Chen, Yanping Zhao, Jiwen Sun, Qian Zhang, Yan‐Tao Wu, Yingan Liang, Jie You, Guohai Hu, Xue‐Qi Tian, Sha Liao, Bao‐Quan Fu, Ao Chen, Xue‐Peng Cai, Huanming Yang, Jian Wang, Xin Jin, Xun Xu, Wan‐Zhong Jia, Junhua Li, Hong‐Bin Yan   +35 more
wiley   +1 more source

The role of monocytes and macrophages in idiopathic inflammatory myopathies: insights into pathogenesis and potential targets. [PDF]

Front Immunol
Izuka S, Komai T, Tsuchida Y, Tsuchiya H, Okamura T, Fujio K.   +5 more
europepmc   +1 more source

A Self-Assembled Metabolic Regulator Reprograms Macrophages to Combat Cytokine Storm and Boost Sepsis Immunotherapy. [PDF]

Research (Wash D C)
Zhuang J, Hai Y, Lu X, Sun B, Fan R, Zhang B, Wang W, Han B, Luo L, Yang L, Zhang C, Zhao M, Wei G.   +12 more
europepmc   +1 more source

Gold and Silver Nanoparticles Efficiently Modulate the Crosstalk Between Macrophages and Cancer Cells. [PDF]

Int J Nanomedicine
Adamecz DI, Veres É, Papp C, Árva H, Rónavári A, Marton A, Vizler C, Gácser A, Kónya Z, Igaz N, Kiricsi M.   +10 more
europepmc   +1 more source