Results 31 to 40 of about 1,540,630 (392)
Journal of Lipid Research, 2003 Human monocyte-derived foam cell macrophages (HMFCs) are resistant to cholesterol efflux mediated by physiological acceptors. The role of the plasma membrane in regulating depletion of free cholesterol (FC) and of cholesteryl ester (CE) was investigated ...
Sue M. Liu +6 more
doaj +1 more source
Macrophage migration inhibitory factor in acute kidneyinjury
Frontiers in Physiology, 2022 Acute kidney injury (AKI) is a complex clinical syndrome with multiple etiologies and pathogenesis, which lacks early biomarkers and targeted therapy.
Yiwei Du, Hao Hao, Heng Ma, Hongbao Liu
doaj +1 more source
Ironing Out the Details: How Iron Orchestrates Macrophage Polarization
Frontiers in Immunology, 2021 Iron fine-tunes innate immune responses, including macrophage inflammation. In this review, we summarize the current understanding about the iron in dictating macrophage polarization.
Yaoyao Xia +9 more
doaj +1 more source
Treating Macrophages with Anti-inflammatory Nanoparticles as a Strategy to Improve Muscle Repair [PDF]
, 2019 The macrophage is an immune cell that is involved in host defense. More recent research, however, has revealed that they also play a central role in mediating the skeletal muscle regenerative process.
Yan, Derek
core +1 more source
Critical Care, 2021 Polymorphonuclear neutrophils (PMNs) play an important role in sepsis-related acute lung injury (ALI). Accumulating evidence suggests PMN-derived exosomes as a new subcellular entity acting as a fundamental link between PMN-driven inflammation and tissue
Yang Jiao +8 more
semanticscholar +1 more source
Antimycobacterial Effect of Selenium Nanoparticles on Mycobacterium tuberculosis
Frontiers in Microbiology, 2020 Tuberculosis (TB) remains the leading cause of death from a single infection agent worldwide. In recent years, the occurrence of TB cases caused by drug-resistant strains has spread, and is expected to continue to grow.
Hector Estevez +10 more
doaj +1 more source
Macrophage autophagy in macrophage polarization, chronic inflammation and organ fibrosis
Frontiers in Immunology, 2022 As the essential regulators of organ fibrosis, macrophages undergo marked phenotypic and functional changes after organ injury. These changes in macrophage phenotype and function can result in maladaptive repair, causing chronic inflammation and the ...
Jun-Hao Wen +5 more
doaj +1 more source
Macrophage Polarization and Its Role in Liver Disease
Frontiers in Immunology, 2021 Macrophages are important immune cells in innate immunity, and have remarkable heterogeneity and polarization. Under pathological conditions, in addition to the resident macrophages, other macrophages are also recruited to the diseased tissues, and ...
Cheng Wang +7 more
semanticscholar +1 more source
Osteopontin ablation ameliorates muscular dystrophy by shifting macrophages to a pro-regenerative phenotype. [PDF]
, 2016 In the degenerative disease Duchenne muscular dystrophy, inflammatory cells enter muscles in response to repetitive muscle damage. Immune factors are required for muscle regeneration, but chronic inflammation creates a profibrotic milieu that exacerbates
Barton, Elisabeth R +7 more
core +2 more sources
Macrophages in xenotransplantation [PDF]
Korean Journal of Transplantation, 2019 Xenotransplantation refers to organ transplantation across species. Immune rejection of xenografts is stronger and faster than that of allografts because of significant molecular differences between species. Recent studies have revealed the involvement of macrophages in xenograft and allograft rejections.
openaire +4 more sources