Results 21 to 30 of about 746,406 (260)

Mesoporous Silica Nanoparticles as a Potential Platform for Vaccine Development against Tuberculosis

Pharmaceutics, 2020
The increasing emergence of new strains of Mycobacterium tuberculosis (Mtb) highly resistant to antibiotics constitute a public health issue, since tuberculosis still constitutes the primary cause of death in the world due to bacterial infection. Mtb has
Sandra Montalvo-Quirós, María Vallet-Regí, Ainhoa Palacios, Juan Anguita, Rafael C. Prados-Rosales, Blanca González, Jose L. Luque-Garcia   +6 more
doaj   +1 more source

Leukocyte-Specific Morrbid Promotes Leukocyte Differentiation and Atherogenesis

Research, 2023
Monocyte-to-M0/M1 macrophage differentiation with unclear molecular mechanisms is a pivotal cellular event in many cardiovascular diseases including atherosclerosis.
Di Xiang, Lei Jiang, Qiong Yuan, Yang Yu, Ruiming Liu, Meiting Chen, Zheng Kuai, Wendy Zhang, Fan Yang, Tingting Wu, Zhiyu He, Zuhui Ke, Wanzi Hong, Pengcheng He, Ning Tan, Yeying Sun, Zhen Shi, Xuebiao Wei, Jianfang Luo, Xiaoqiu Tan, Yuqing Huo, Gangjian Qin, Chunxiang Zhang   +22 more
doaj   +1 more source

Comparative study of the ability of Leishmania mexicana promastigotes and amastigotes to alter macrophage signalling and functions [PDF]

, 2010
Leishmania alternates between two morphologically different stages: promastigotes and amastigotes. While the majority of reports focused on how the promastigote form can alter macrophage signalling and function, fewer reports investigated signalling ...
Hassani, K., Westra, E.R., Abu-Dayyeh, I., Edze R. Westra, Kasra Hassani, Issa Abu-Dayyeh, Mottram, J.C., Olivier, M., Jeremy C. Mottram, Martin Olivier   +9 more
core   +1 more source

Ratio of CD68/CD163 in Breast Carcinoma with and without Axillary Lymph Node Metastatic

Folia Medica Indonesiana, 2021
Tumor and its microenvironment can interact each other. Macrophage is part of tumor microenvironment. New drugs targeting specific superficial receptor of macrophage or cytokine of macrophage polarization have been found.
Priangga Adi Wiratama, Willy Sandhika
doaj   +1 more source

Solanum nigrum induces macrophage activation through TLR4-mediated activation of JNK and macrophage autophagy through TLR4-mediated activation of p38 and JNK

Food and Agricultural Immunology, 2022
In this study, we investigated the effect of Solanum nigrum aerial parts (SNAP) on macrophage activation and macrophage autophagy in RAW264.7 cells. SNAP increased the production of immunostimulatory factors and phagocytosis in RAW264.7 cells.
Ju Hyung Yu, Min Yeong Choi, So Jung Park, Na Gyeong Geum, Jae Won Lee, Gwang Hun Park, Hyun Ji Eo, Jin Boo Jeong   +7 more
doaj   +1 more source

Human circulating eosinophils secrete macrophage migration inhibitory factor (MIF). Potential role in asthma [PDF]

, 1998
Macrophage migration inhibitory factor (MIF) is a potent proinflammatory mediator that has been shown to potentiate lethal endotoxemia and to play a potentially important regulatory role in human acute respiratory distress syndrome (ARDS).
N Hirani, S C Donnelly, Bucala, R, Donnelly, Seamas C, A P Greening, A G Rossi, Rossi, Adriano G, Hirani, N, C Haslett, I Rahman, R Bucala, Metz, C N, C N Metz, Rahman, I, Haslett, Christopher, Greening, A. P.   +15 more
core   +1 more source

Antimycobacterial Effect of Selenium Nanoparticles on Mycobacterium tuberculosis

Frontiers in Microbiology, 2020
Tuberculosis (TB) remains the leading cause of death from a single infection agent worldwide. In recent years, the occurrence of TB cases caused by drug-resistant strains has spread, and is expected to continue to grow.
Hector Estevez, Ainhoa Palacios, David Gil, Juan Anguita, Juan Anguita, Maria Vallet-Regi, Maria Vallet-Regi, Blanca González, Blanca González, Rafael Prados-Rosales, Jose L. Luque-Garcia   +10 more
doaj   +1 more source

Organizing the interface—Plasma membrane architecture and receptor dynamics in virus‐cell interactions

FEBS Letters, EarlyView.
Plasma membranes contain dynamic nanoscale domains that organize lipids and receptors. Because viruses operate at similar scales, this architecture shapes early infection steps, including attachment, receptor engagement, and entry. Using influenza A virus and HIV‐1 as examples, we highlight how receptor nanoclusters, multivalent glycan interactions ...
Jan Schlegel, Christian Sieben
wiley   +1 more source

CSF-1 as a regulator of macrophage activation and immune responses [PDF]

, 2003
Macrophage activation is a key determinant of susceptibility and pathology in a variety of inflammatory diseases. The extent of macrophage activation is tightly regulated by a number of pro-inflammatory cytokines (e.g.
Sweet, MJ, Sweet, Matthew J, Hume, David A, Hume, DA   +3 more
core  

A randomised trial of granulocyte-macrophage colony-stimulating factor for neonatal sepsis: outcomes at 2 years [PDF]

, 2012
The authors performed a randomised trial in very preterm small-for-gestational age (SGA) babies to determine if prophylaxis with granulocyte-macrophage colony-stimulating factor (GM-CSF) improves outcomes (the PROGRAMS trial).
Carr, R., Robert Carr, Caroline Dore, Redshaw, ME, Petrou, Stavros, Marlow, N, Cowan, Frances M, Marlow, Neil, Nishma Patel, Neil Marlow, Timothy Morris, Dore, C., Carr, Robert, Maggie E Redshaw, Redshaw, M. E., Brocklehurst, P., Modi, N., Redshaw, Margaret, Redshaw, Maggie E., Patel, N., Morris, T., Peter Brocklehurst, Petrou, S, Stavros Petrou, Carr, R, Modi, Neena, Modi, N, Brocklehurst, Peter, Cowan, FM, Patel, Nishma, Morris, Timothy, Neena Modi, Morris, T, Dore, C, Frances M Cowan, Brocklehurst, P, Cowan, F. M., Cowan, Frances M., Patel, N, Dore, Caroline   +39 more
core   +1 more source