Results 191 to 200 of about 851,361 (268)

Dynamic Mechanical Loading Modulates Extracellular Vesicle Production and Cargo in Meniscus Fibrochondrocytes

Advanced Materials Interfaces, EarlyView.
Dynamic mechanical loading of outer meniscus fibrochondrocytes increases extracellular vesicle (EV) yield and alters EV composition. When applied to progenitor cells, these mechanically primed EVs modulate the expression of matrix‐related genes.
Catherine Cheung, Zizhao Li, Sung‐Han Jo, Se‐Hwan Lee, Il Keun Kwon, Jina Ko, Su Chin Heo   +6 more
wiley   +1 more source

The mechanism of action and therapeutic potential of macrophages in osteoporosis: from polarization balance to targeted regulation. [PDF]

Front Immunol
Liu C, Wang T, Ren Z, Luo J, Wang Z, Liang Y, Peng B.   +6 more
europepmc   +1 more source

Multilayered Digital Microfluidic Chip for Cell‐Based Assays

Advanced Materials Interfaces, EarlyView.
A multilayered digital microfluidic (mDMF) chip architecture is introduced to improve throughput and robustness in cell‐based assays. By multilayering electrode components and dielectric layers on glass, this design significantly reduces actuation voltage, maintains reliability, and enables expansion of the operational area with minimum current leakage.
Mert Ozden, Oksana K. Savchak, Burcu Gumuscu   +2 more
wiley   +1 more source

Engineered CCR2 positive macrophages coordinate immunoregulation with neural regeneration and matrix remodeling after spinal cord injury. [PDF]

Theranostics
Zhao Y, Xie T, Ma Y, Wang Y, Liu S, Li H, Liu Y, Liu R, Xu H, Ju C, Wu W, Wang Y, He S, Luo R, Huang D, Jia S, Hu C, Yan L, Wang Z, Zhu L.   +19 more
europepmc   +1 more source

Negotiating in a Foreign Land: Understanding the Curious Interactions Between Intracellular Mitochondria and Internalized Nanoparticles

Advanced Materials Interfaces, EarlyView.
Therapeutic nano‐drug delivery systems interact with cellular mitochondria in a multitude of ways. While the complexity of such interactions disrupts the mitochondrial electron transport chain and increases reactive oxygen species production, thereby contributing to nanoparticle toxicity, they also present unique theranostic opportunities in diseases ...
Sourav Bhattacharjee
wiley   +1 more source

Targeting the Fra2/LCN2 axis attenuates PM_2.5-aggravated asthma by suppressing M2 macrophage ferroptosis. [PDF]

Redox Biol
Wang C, Yang S, Zhang Z, Gao H, Niu Q, Wu J, Lv S, Mei Q, Gao C, Jing Y, Liu X.   +10 more
europepmc   +1 more source

Maskless Fabrication of PLA‐Based Neural Arrays for CNS Recording and Stimulation

Advanced Materials Interfaces, EarlyView.
Biodegradable neural interfaces enable bidirectional communication with the CNS. Through electrochemical characterization, ageing tests with impedance monitoring, and in vivo validation, we assess the performance of PLA‐based epicortical and spinal implants.
Anna De Salvo, Federica Velluto, Ilenia Sergi, Michele Di Lauro, Verónica Barranco‐Maresca, Elena Alonso‐Calviño, Yasmina Hernández‐Martín, Juan Aguilar, Juliana M. Rosa, María C. Serrano, Carolina Giulia Ferroni, Federico Rondelli, Elisa López‐Dolado, Luciano Fadiga, Fabio Biscarini   +14 more
wiley   +1 more source

Hemodynamics and matrix stiffness shape the pathogenicity of SPP1⁺ macrophages. [PDF]

Front Immunol
Zhang H, Han J, Zhu S, Yi M, Fan K, Chang R, Shi Y, Dong H.   +7 more
europepmc   +1 more source

Flexible Wide Bandgap Electrode System for In situ Cell Sensing and Irreversible Electroporation

Advanced Materials Interfaces, EarlyView.
The paper reports the design and wafer‐level microfabrication of a long‐lived, flexible 3C‐SiC electrode capable of sensitive and in situ cell sensing, as well as electroporation ablation. The work demonstrates a biocompatible and durable electrode platform that can perform reliable electrical interfacing with biological tissues over extended periods ...
Minh Anh Huynh, Sharda Yadav, Tuan‐Khoa Nguyen, Nam‐Trung Nguyen   +3 more
wiley   +1 more source

Targeting macrophages in liver fibrosis. [PDF]

Front Immunol
González Del Barrio L, Ipsen DH, Pfister DR, Hancz D, Scott CL.   +4 more
europepmc   +1 more source