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Macrophages in cholangiopathies

Current Opinion in Gastroenterology, 2021
Purpose of review Cholangiopathies are a heterogeneous class of liver diseases where cholangiocytes are the main targets of liver injury. Although available and emerging therapies mainly target bile acids (ursodeoxycholic acid/UDCA, 24-Norursodeoxycholic acid/norUDCA) and related signaling pathways (obeticholic acid, fibrates ...
Alix, Bruneau   +2 more
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Macrophages and cancer

Frontiers in Bioscience, 2008
Macrophages are ubiquitous cells physiologically involved in a variety of processes including pathogen destruction, inflammation, tissue repair and remodeling. They have a highly plastic phenotype and their functional polarization is determined by cytokines and factors found within local microenvironments.
Alessandra, Nardin   +1 more
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The Macrophage

2011
Macrophages are a diverse phenotype of professional phagocytic cells derived from bone-marrow precursors and parent monocytes in the peripheral blood. They are essential for the maintenance and defence of host tissues, doing so by sensing and engulfing particulate matter and, when necessary, initiating a pro-inflammatory response.
Chris P, Verschoor   +2 more
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Atherosclerosis and Macrophages

Acta Pathologica Japonica, 1989
Atherosclerosis is undoubtedly a disease of many facets and in this review we have merely touched one angle of this issue. The best‐established cause of the disease is hyper‐cholesterolemia. Since the important role of macrophages in lipoprotein metabolism has been confirmed, current interest is focused on the role of macrophages in atherosclerosis ...
T, Watanabe   +3 more
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The macrophage

BioEssays, 1995
AbstractThe macrophage plays an important role in host development and physiology, and in pathogenesis of many infectious, immunologic and degenerative disease processes. It displays marked heterogeneity of phenotype in different tissues, reflecting local interactions with other cell types, and contributes to host homeostasis through a varied ...
openaire   +2 more sources

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