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Macrophage Procoagulants

Haemostasis, 2009
Monocytes and macrophages can be induced to produce tissue factor. Recent data suggest that macrophages make other products involved in the extrinsic coagulation pathway. These include vitamin K-dependent factors, factor X activators and a prothrombinase.
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Macrophages and the glucocorticoids

Journal of Neuroimmunology, 1992
Macrophages fulfill such functions as (i) housekeeping and scavenging, (ii) protective and defense, and (iii) memory. Glucocorticoids are hormones also used as anti-inflammatory and immuno-suppressive drugs. They act on the many functions of macrophages, mainly by interfering with functions (ii) and (iii).
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Macrophages in Inflammation

Current Drug Target -Inflammation & Allergy, 2005
The inflammatory process is usually tightly regulated, involving both signals that initiate and maintain inflammation and signals that shut the process down. An imbalance between the two signals leaves inflammation unchecked, resulting in cellular and tissue damage.
Nagatoshi, Fujiwara, Kazuo, Kobayashi
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The Macrophage and Fibrinolysis

Seminars in Thrombosis and Hemostasis, 1996
The monocyte/macrophage plays a central role in fibrinolysis. Cell-surface of components of the plasminogen activator system leads to the elaboration of plasmin, which facilitates degradation of fibrin in the pericellular environment, as well as activation of matrixins, which promote degradation of matrix components.
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Transfecting Macrophages

2018
Transfection is defined as the transfer of foreign nucleic acids into cells. In general, transfection may achieve either overexpression of a gene by the transfer of plasmid DNA or suppression of gene expression by RNA interference after transfer of small interfering RNA.
Andrea-Anneliese, Keller   +4 more
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Macrophagic myofasciitis

Current Rheumatology Reports, 2000
A most unusual inflammatory myopathy, called macrophagic myofasciitis, first described by the Groupe d'Etudes et Recherche sur les Maladies Musculaires Acquises et Dysimmunitaires (GERMMAD), a specific branch of the Association Française contre les Myopathies was recorded with an increasing frequency from 1993 in the main French myopathologic centers ...
P, Cherin, R K, Gherardi
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The Biology of Macrophages

2014
Macrophages are part of the innate immune system, recognizing, engulfing, and destroying many potential pathogens including bacteria, pathogenic protozoa, fungi, and helminths. The destructive potential of macrophages and their ability to secrete regulators of the function of neighboring cells contribute to many aspects of homeostasis.
Sasmono, R.T., Hume, D. A.
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Macrophages and Pregnancy

Reproductive Sciences, 2008
During implantation, apoptosis is critical for the appropriate tissue remodeling of the maternal decidua and invasion of the developing embryo. Yet the regulation of apoptosis is also imperative for a successful pregnancy. The quick and effective removal of apoptotic cells by tissue macrophages represents an essential process, which prevents the ...
Gil, Mor, Kaori, Koga
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Lymphokines and macrophages

Cellular Immunology, 1983
It is a pleasure and a privilege to be here today to honor Lewis Thomas. As I look out on this distinguished audience and see so many good friends, it brings on an attack of nostalgia for the early sixties on the sixth floor of Building D in Bellevue. Those years with Jerry and Lew were some of the most exciting and satisfying of my career. The sixties
J R, David   +4 more
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Macrophages and the kidney

Current Opinion in Nephrology and Hypertension, 2004
Macrophage infiltration is a hallmark of all forms of inflammatory and non-inflammatory renal injury. However, the classical view of macrophages as cells that cause injury has been superseded with evidence of their heterogeneous role, i.e. with involvement in all stages of the inflammatory process including tissue repair and healing.
Heather M, Wilson   +2 more
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