Results 311 to 320 of about 2,020,072 (390)

Differential Phase Contrast Imaging to Predict MSC Immune Function

Advanced Healthcare Materials, EarlyView.
This work employs quantitative differential phase contrast (qDPC) imaging technique to non‐invasively extract morphological features from live Mesenchymal Stromal Cells (MSCs) for single cell prediction on cell immunomodulatory capacity. This work establishes a foundation for scalable, non‐destructive monitoring of MSCs immunomodulatory capacity ...
Kejie Rui, Priyanka Priyadarshani, Adrian Ross Liversage, Carlos Munoz, Steven Stice, Luke J. Mortensen   +5 more
wiley   +1 more source

Macrophages-Target and Tool in Tumor Treatment: Insights from Ovarian Cancer. [PDF]

Cancers (Basel)
Górczak M, Kiraga Ł.
europepmc   +1 more source

A Novel Core–Shell Hydrogel 3D Model for Studying Macrophage Mechanosensing and Foreign Body Giant Cell Formation

Advanced Healthcare Materials, EarlyView.
The foreign body response (FBR) to biomaterials is primarily driven by macrophages, which often fuse into destructive foreign body giant cells (FBGCs). To address the limited understanding of FBGC formation, a novel microscale core–shell hydrogel 3D model is developed using heterogeneous alginate‐collagen microcapsules with varying stiffness, offering ...
Manisha Mahanty, Wenquan Ou, Xiaoping Zhu, Jonathan S Bromberg, Xiaoming He, Shaik O. Rahaman   +5 more
wiley   +1 more source

Genomic Analysis Defines Increased Circulating, Leukemia-Induced Macrophages That Promote Immune Suppression in Mouse Models of FGFR1-Driven Leukemogenesis. [PDF]

Cells
Zhang T, Matsunaga A, Lu X, Fang H, Chatterjee N, Alimadadi A, Mori SF, Fang X, Wang G, Shi H, Zhang L, Hedrick CC, Cheng B, Hu T, Cowell JK.   +14 more
europepmc   +1 more source

A Study on the Phagocytosis of Macrophage

, 1969
Kensuke Ozu
openalex   +2 more sources

Impact of Nanoparticle Stiffness on Endosomal Escape and Signaling Pathways in Cytosolic Delivery

Advanced Healthcare Materials, EarlyView.
Nanoparticle (NP) stiffness affects cellular uptake, but its impact on intracellular distribution remains unclear. This study synthesizes silica nanocapsules with varying stiffness, inspired by viral mechanisms, and applies assays to measure cellular uptake and escape efficiency.
Yali Zhang, Yue Hui, Zichao Guo, Dawei Liu, Yun Liu, Huajian Gao, Chun‐Xia Zhao   +6 more
wiley   +1 more source

IL-1β⁺ tumor-associated macrophages accelerate glioblastoma progression by amplifying the PGE2-EP4 signaling. [PDF]

J Neuroinflammation
Liang H, Yang Q, Zhong B, Li D, Wu F, Zhang J, Guo C, Zhu Z, Feng M, Zhang Y, Peng H.   +10 more
europepmc   +1 more source

Translational Considerations for Injectable Biomaterials and Bioscaffolds to Repair and Regenerate Brain Tissue

Advanced Healthcare Materials, EarlyView.
The repair and regeneration of brain tissue faces both biological and technical challenges. Injectable bioscaffolds offer new opportunities to stimulate tissue regrowth in the brain by recruiting neural stem cells. Here, the translational issues are reviewed that need to be address to advance this promising new therapeutic approach from the bench to ...
Michel Modo, Alena Kisel
wiley   +1 more source

Interplay of human macrophage response and natural resistance of infection by L. (V.) panamensis to pentavalent antimony. [PDF]

PLoS Negl Trop Dis
Fernández OL, Belew AT, Rosales-Chilama M, Sánchez-Hidalgo A, Colmenares M, Saravia NG, El-Sayed NM.   +6 more
europepmc   +1 more source

Multiscale Profiling of Nanoscale Metal‐Organic Framework Biocompatibility and Immune Interactions

Advanced Healthcare Materials, EarlyView.
A multi‐scale, hierarchical ‘Safety‐by‐Design’ pipeline combining machine learning, ex vivo human blood assays, and in vivo models enables the systematic immunotoxicity and biocompatibility profiling of nanoscale metal‐organic frameworks, accelerating their safe clinical translation. Abstract The clinical translation of metal‐organic frameworks (MOFs) –
Yunhui Zhuang, Bárbara B. Mendes, Dhruv Menon, Jhenifer Oliveira, Xu Chen, Fatma Demir Duman, João Conniot, Sergio Mercado, Xiewen Liu, Shi‐Yuan Zhang, João Conde, Rachel E. Hewitt, David Fairen‐Jimenez   +12 more
wiley   +1 more source