Results 321 to 330 of about 2,020,072 (390)

Integrated multi-omics identifies a CD54⁺ iCAF-ITGAL⁺ macrophage niche driving immunosuppression via CXCL8-PDL1 axis in cervical cancer. [PDF]

Mol Cancer
Chen F, Bai G, Liu Q, He G, Ding Z, Liang J, Wang N, Qiu J, Hua K.   +8 more
europepmc   +1 more source

ROS‐Scavenging Multifunctional Microneedle Patch Facilitating Wound Healing

Advanced Healthcare Materials, EarlyView.
A reactive oxygen species (ROS) scavenging and immunomodulatory microneedle patch based on hyaluronic acid methacrylate (HaMA) and Flightless I (Flii)‐siRNA‐laden arginine functionalized poly (β‐amino ester)/alginate particles is developed for chronic wound healing applications.
Mahshid Kharaziha, Sahar Salehi, Mahshid Shokri, Seyed Mohsen Ahmadi Tafti, Thomas Scheibel   +4 more
wiley   +1 more source

Reprogramming mitochondrial metabolism and epigenetics of macrophages via miR-10a liposomes for atherosclerosis therapy. [PDF]

Nat Commun
Fang F, Wang E, Yang H, Zhao T, Wang Q, Zhang Z, Song Y, Liu X.   +7 more
europepmc   +1 more source

Engineering Extracellular Microenvironments: The Impact of Fibrous Materials on Cell Behavior

Advanced Healthcare Materials, EarlyView.
Fibrous structures are key elements of the native extracellular matrix and crucial for directing cell behavior. This review discusses how fiber properties such as composition, diameter, and alignment affect cell responses in 2D and 3D systems. Strategies for integrating fibrous cues into engineered tissues are highlighted, and future directions for ...
Zan Lamberger, Gregor Lang
wiley   +1 more source

Long non-coding RNAs: key orchestrators of macrophage polarization in breast cancer. [PDF]

Cancer Cell Int
Ghorbaninezhad F, Vanan AG, Rostami S, Vaezi F, Doachi R, Hafshejani ZA, Ehteshaminia Y, Nouri M, Mohammadi NG, Talebileili M, Tahmasebi S, Safarzadeh E.   +11 more
europepmc   +1 more source

Inhalability and Bioactivity of Spray‐Dried versus Pressurized Gas eXpanded Liquid Technology‐Processed Yeast Beta‐Glucan Microparticles for Anti‐Fibrotic Therapies

Advanced Healthcare Materials, EarlyView.
PGXTEC) liquid technology is utilized to develop highly respirable yeast beta‐glucan (YBG) microparticles for the treatment of pulmonary fibrosis. Compared to conventionally processed spray‐dried YBG, PGXTEC‐YBG exhibits greatly improved aerodynamic properties, enhanced pro‐fibrotic macrophage uptake, and effective downregulation of pro‐fibrotic ...
Nate Dowdall, Safaa Naiel, Quan Zhou, Pareesa Ali, Tamana Rubina Yousof, Emily Wong, Ricardo Couto, Byron Yépez, Bernhard Seifried, Paul Moquin, Rod Rhem, Myrna Dolovich, Martin Rainer Kolb, Kjetil Ask, Todd Hoare   +14 more
wiley   +1 more source

Propolis-loaded liposomes (ProLip) enhance macrophage-mediated immunomodulation and suppress breast cancer cell proliferation. [PDF]

Sci Rep
Mohd Zain H, Muhamad M, Nik Mohamed Kamal NNS.   +2 more
europepmc   +1 more source

Advanced Nanoparticle Therapeutics for Targeting Neutrophils in Inflammatory Diseases

Advanced Healthcare Materials, EarlyView.
This review highlights recent advances in nanoparticle‐based strategies to modulate neutrophil activity in inflammatory diseases. By targeting inflammatory neutrophils, NET formation, and neutrophil apoptosis or recruitment, these approaches aim to improve therapeutic precision.
Min Ji Byun, Elizabeth S. Nakasone, Ha Eun Shin, Hyojin Lee, Jong‐Chan Park, Wonhwa Lee, Wooram Park, Chun Gwon Park, Juwon Park, Se‐Na Kim   +9 more
wiley   +1 more source

The multifaceted role of macrophages in kidney physiology and diseases. [PDF]

Front Immunol
Ma Y, Yang F, Yang J, Wang K, Hu J, Wu Q.   +5 more
europepmc   +1 more source

Coordinated Development of Immune Cell Populations in Vascularized Skin Organoids from Human Induced Pluripotent Stem Cells

Advanced Healthcare Materials, EarlyView.
Vascularized skin organoids are developed from human induced pluripotent stem cells and contain macrophages, Langerhans cells, and neutrophils. Vascularized skin organoids offer a transformative platform to model skin biology and enable mechanistic investigations of inflammatory and hematologic skin disorders.
Mitchell Mostina, Jane Sun, Seen Ling Sim, Imaan A. Ahmed, Fernando Souza‐Fonesca‐Guimaraes, Ernst J. Wolvetang, Jason Brown, Snehlata Kumari, Kiarash Khosrotehrani, Abbas Shafiee   +9 more
wiley   +1 more source