Results 341 to 350 of about 1,982,911 (405)

Emerging Advancements in Metabolic Properties of Macrophages within Disease Microenvironment for Immune Therapy. [PDF]

J Innate Immun
Zhao F, Yue Z, Zhang L, Qi Y, Sun Y, Wang S, Tian Q.   +6 more
europepmc   +1 more source

ACPA-Induced ATP release and K⁺ efflux trigger NLRP3 inflammasome activation in rheumatoid arthritis. [PDF]

Cell Commun Signal
Cai L, Zhang K, Gao J, Xiao B, Li M, Meng X, Chen Z, Chen X, Chen S, Li J.   +9 more
europepmc   +1 more source

Macrophages as tools and targets in cancer therapy

Nature Reviews Drug Discovery, 2022
Tumour-associated macrophages are an essential component of the tumour microenvironment and have a role in the orchestration of angiogenesis, extracellular matrix remodelling, cancer cell proliferation, metastasis and immunosuppression, as well as in ...
Alberto Mantovani, Federica Marchesi, Cecilia Garlanda   +2 more
exaly   +2 more sources

Tumor-Associated Macrophages in Tumor Immunity

Frontiers in Immunology, 2020
Tumor-associated macrophages (TAMs) represent one of the main tumor-infiltrating immune cell types and are generally categorized into either of two functionally contrasting subtypes, namely classical activated M1 macrophages and alternatively activated ...
Xiaojian Wang, Ting Zhang, Hanno Steen
exaly   +2 more sources

Macrophages as regulators of tumour immunity and immunotherapy

Nature Reviews Immunology, 2019
David G Denardo, Brian Ruffell
exaly   +2 more sources

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Targeting macrophages: therapeutic approaches in cancer

Nature Reviews Drug Discovery, 2018
Luca Cassetta, Jeffrey W Pollard
exaly   +2 more sources

Tissue-resident macrophages provide a pro-tumorigenic niche to early NSCLC cells

Nature, 2021
Brian D Brown, Ina Beintner, Barbara B Maier   +2 more
exaly   +2 more sources

Functional polarization of tumour-associated macrophages by tumour-derived lactic acid

Nature, 2014
Oscar Colegio, Vikram Jairam, Nika Cyrus
exaly   +2 more sources

Tumor-Associated Macrophages: Recent Insights and Therapies

Frontiers in Oncology, 2020
Macrophages, which have functions of engulfing and digesting foreign substances, can clear away harmful matter, including cellular debris and tumor cells.
Ziwei Tang, R M Bianchi, Xikun Zhou
exaly   +2 more sources

Engineering Macrophages for Cancer Immunotherapy and Drug Delivery

Advanced Materials, 2020
Macrophages play an important role in cancer development and metastasis. Proinflammatory M1 macrophages can phagocytose tumor cells, while anti‐inflammatory M2 macrophages such as tumor‐associated macrophages (TAMs) promote tumor growth and invasion ...
Yuqiong Xia, Lang Rao, Zhongliang Wang
exaly   +2 more sources