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Reproductive Sciences, 2008
During implantation, apoptosis is critical for the appropriate tissue remodeling of the maternal decidua and invasion of the developing embryo. Yet the regulation of apoptosis is also imperative for a successful pregnancy. The quick and effective removal of apoptotic cells by tissue macrophages represents an essential process, which prevents the ...
Gil Mor, Kaori Koga
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During implantation, apoptosis is critical for the appropriate tissue remodeling of the maternal decidua and invasion of the developing embryo. Yet the regulation of apoptosis is also imperative for a successful pregnancy. The quick and effective removal of apoptotic cells by tissue macrophages represents an essential process, which prevents the ...
Gil Mor, Kaori Koga
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Comparative Immunology, Microbiology and Infectious Diseases, 1985
The role of macrophages is essential in the development of a normal immune response. Not only are these cells involved in the initiation of this response by presenting antigens to lymphocytes and by producing Interleukin I, but they also participate in the various phenomena of cellular co-operation and regulation.
E Schneider, M Dy
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The role of macrophages is essential in the development of a normal immune response. Not only are these cells involved in the initiation of this response by presenting antigens to lymphocytes and by producing Interleukin I, but they also participate in the various phenomena of cellular co-operation and regulation.
E Schneider, M Dy
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Macrophages and the glucocorticoids
Journal of Neuroimmunology, 1992Macrophages fulfill such functions as (i) housekeeping and scavenging, (ii) protective and defense, and (iii) memory. Glucocorticoids are hormones also used as anti-inflammatory and immuno-suppressive drugs. They act on the many functions of macrophages, mainly by interfering with functions (ii) and (iii).
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Journal of Leukocyte Biology, 1994
Abstract Macrophages are supposed to play a key role in inflammatory and tumor angiogenesis. Their importance derives from (1) their ubiquitous presence in normal and especially inflamed tissues, (2) their potential to become activated in response to appropriate stimuli, and (3) their repertoire of secretory products.
Clemens Sorg +4 more
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Abstract Macrophages are supposed to play a key role in inflammatory and tumor angiogenesis. Their importance derives from (1) their ubiquitous presence in normal and especially inflamed tissues, (2) their potential to become activated in response to appropriate stimuli, and (3) their repertoire of secretory products.
Clemens Sorg +4 more
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Journal of Applied Physiology, 1986
The alveolar macrophage is one of the few tissue macrophage populations readily accessible to study both in the human and in animals. Since harvesting of these cells by bronchoalveolar lavage was first described in 1961, alveolar macrophages have been extensively investigated.
Z. A. Cohn, A. O. Fels
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The alveolar macrophage is one of the few tissue macrophage populations readily accessible to study both in the human and in animals. Since harvesting of these cells by bronchoalveolar lavage was first described in 1961, alveolar macrophages have been extensively investigated.
Z. A. Cohn, A. O. Fels
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Current Opinion in Nephrology and Hypertension, 2004
Macrophage infiltration is a hallmark of all forms of inflammatory and non-inflammatory renal injury. However, the classical view of macrophages as cells that cause injury has been superseded with evidence of their heterogeneous role, i.e. with involvement in all stages of the inflammatory process including tissue repair and healing.
Heather M. Wilson +2 more
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Macrophage infiltration is a hallmark of all forms of inflammatory and non-inflammatory renal injury. However, the classical view of macrophages as cells that cause injury has been superseded with evidence of their heterogeneous role, i.e. with involvement in all stages of the inflammatory process including tissue repair and healing.
Heather M. Wilson +2 more
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2002
Publisher Summary This chapter examines macrophages, which are a family of mononuclear leukocytes that are widely distributed throughout most tissues. They vary considerably in phenotype depending on the local microenvironment, involved in the scavenging of dying cells, pathogens, and molecules through phagocytosis and endocytosis.
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Publisher Summary This chapter examines macrophages, which are a family of mononuclear leukocytes that are widely distributed throughout most tissues. They vary considerably in phenotype depending on the local microenvironment, involved in the scavenging of dying cells, pathogens, and molecules through phagocytosis and endocytosis.
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The Macrophage and Fibrinolysis [PDF]
Seminars in Thrombosis and Hemostasis, 1996 The monocyte/macrophage plays a central role in fibrinolysis. Cell-surface of components of the plasminogen activator system leads to the elaboration of plasmin, which facilitates degradation of fibrin in the pericellular environment, as well as activation of matrixins, which promote degradation of matrix components.
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Macrophages, inflammation, and insulin resistance.
Annual Review of Physiology, 2010Obesity induces an insulin-resistant state in adipose tissue, liver, and muscle and is a strong risk factor for the development of type 2 diabetes mellitus.
J. Olefsky, C. Glass
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Current Drug Target -Inflammation & Allergy, 2005
The inflammatory process is usually tightly regulated, involving both signals that initiate and maintain inflammation and signals that shut the process down. An imbalance between the two signals leaves inflammation unchecked, resulting in cellular and tissue damage.
Kazuo Kobayashi, Nagatoshi Fujiwara
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The inflammatory process is usually tightly regulated, involving both signals that initiate and maintain inflammation and signals that shut the process down. An imbalance between the two signals leaves inflammation unchecked, resulting in cellular and tissue damage.
Kazuo Kobayashi, Nagatoshi Fujiwara
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