Results 171 to 180 of about 854 (190)

Macroprolactinemia presenting like a pituitary tumor

The American Journal of Medicine, 1985
A serum prolactin level greater than 200 ng/ml is almost pathognomonic of a pituitary tumor in a nonpregnant woman. A patient with a three-year history of documented serum prolactin levels of 350 to 400 ng/ml and no evidence of a pituitary adenoma on computed axial tomographic scanning was recently studied.
R D, Jackson, J, Wortsman, W B, Malarkey
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Macroprolactinemia, like hyperprolactinemia, may promote platelet activation

Endocrine, 2010
Insulin resistance, which provides a convenient milieu for platelet activation, has been closely associated with atherosclerotic disorders. Although it often accompanies hyperprolactinemia, findings conflict concerning its clinical impact in macroprolactinemia.
Inan, Anaforoglu, Melek Eda, Ertorer, Ilknur, Kozanoglu, Birsel, Unal, Filiz Eksi, Haydardedeoglu, Okan, Bakiner, Emre, Bozkirli, Neslihan Bascil, Tutuncu, Nilgun Guvener, Demirag   +8 more
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Macroprolactinemia: The Consequences of a Laboratory Pitfall

Endocrine, 2003
The objective of this study was to assess the prevalence of macroprolactin, a macromolecule with reduced bioactivity, in hyperprolactinemic patients. Prolactin was measured before and after precipitation of macroprolactin by polyethylene glycol in 306 patients. Only patients with prolactin values >700 mIU/L (n = 270) entered the study.
Erzsébet, Toldy, Zoltán, Löcsei, István, Szabolcs, Miklós I, Góth, Pál, Kneffel, Dominika, Szöke, Gábor L, Kovács   +6 more
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Long-term assessment of patients with macroprolactinemia

Fertility and Sterility, 1988
Three patients presenting with hyperprolactinemia associated with normal menses, retained fertility, and minimal lactation were followed for a period of 5 to 7 years. All had associated thyroid autoimmune disorders (one with chronic thyroiditis and two with Graves' disease).
W B, Malarkey, R, Jackson, J, Wortsman
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Macroprolactinemia. Is treatment necessary?

Hormones (Athens, Greece), 2007
A 26-year old symptom-free woman was admitted to our Clinic for evaluation of hyperprolactinemia. The patient, who had normal menstrual cycles, was found accidentally to have a cystic adnexal mass and was placed on oral contraceptives (OC) for 3 months.
Irene V, Lambrinoudaki, Olga D, Daskalaki, Stathis A, Thomopoulos, Panayiotis, Schinochoritis, Argyris B, Argyropoulos   +4 more
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[Macroprolactinemia in a child].

Archives francaises de pediatrie, 1991
An hyperprolactinemia, with basal serum prolactin levels ranging from 41 to 135 ng/ml was found to be coincidentally associated with psychosocial dwarfism in a 11 year-old boy. Sephadex G 100 exclusion chromatography showed that the predominating form of immunoreactive prolactin levels ranging from 41 to 135 ng/ml was found to be weight, differing from
J, Weill, S, Petit, C, Stuckens, Y, Descamps, A, Racadot, A, Boersma, C, Ponte   +6 more
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The Effect of Macroprolactinemia on Gonadotropin Secretion

The Endocrinologist, 2007
Objectives: Hyperprolactinemia due to monomeric prolactin (m-PRL), is associated with suppression of gonadotropin secretion and gonadal activity. Macroprolactin is thought to be a biologically inactive form of prolactin that has no effects on gonadotropin secretion.
Gonca Tamer, Aysegül Telci, Ferihan Aral, Sema Yarman, Nese Özbey, Harika Boztepe, Faruk Alagöl   +6 more
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Macroprolactinemia in a Patient with Infertility and Hyperprolactinemia

Southern Medical Journal, 2006
A significant number of patients with hyperprolactinemia have macroprolactinemia, a condition characterized by the preponderance of big-big prolactin with normal levels of free prolactin. As macroprolactin does not have biologic activity, such patients do not require further investigations or treatment for hyperprolactinemia. The case of a patient with
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Macroprolactinemia in Childhood and Adolescence: A Cause of Asymptomatic Hyperprolactinemia

Hormone Research in Paediatrics, 2000
Asymptomatic hyperprolactinemias associated with altered proportions of molecular forms of circulating prolactin (PRL) have been reported in adults. The scarce references available in children and adolescents prompted us to report our experience in the evaluation and follow-up of patients with macroprolactinemia.
H L, Fideleff, G, Ruibal, H, Boquete, A, Pujol, A, Sequera, P, Sobrado   +5 more
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IgA-type macroprolactin among 130 patients with macroprolactinemia

Clinical Chemistry and Laboratory Medicine (CCLM)
Abstract Objectives Macroprolactin (macro-PRL) mostly comprises a complex of PRL with IgG. The aim of this study was to clarify whether IgA-type macro-PRL exists and, if so, to elucidate the prevalence of and differences in laboratory data from IgG-type.
Masayuki, Ishihara, Naoki, Hattori, Norito, Nishiyama, Kozo, Aisaka, Takashi, Adachi, Takanori, Saito   +5 more
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