Results 51 to 60 of about 26,388,884 (283)

ADP‐ribosylation: An emerging regulator of the epigenome

Molecular Oncology, EarlyView.
ADP‐ribosylation has emerged as a dynamic epigenetic signaling mechanism that modifies histones and chromatin‐associated proteins. Through coordinated PARylation and MARylation, it integrates with other histone modifications to regulate chromatin structure, transcription factor activity, and gene expression, influencing genome function and disease ...
Cristel V. Camacho, Chenqian Liu, W. Lee Kraus   +2 more
wiley   +1 more source

The anterior talofibular ligament of the ankle: Macroscopic and morphometric study

Journal de la Faculté de Médecine d'Oran, 2022
Introduction - The anterior talofibular ligament represents the anterior bundle of the lateral complex of the ankle. Being the least resistant, it is the first touched in case of lateral sprain of the ankle.
Assia Yabka, Bahia Hamzaoui, Mustapha Baba-Ahmed   +2 more
doaj  

Pharmacological inhibition of the PERK pathway modulates hepatocellular carcinoma growth and immune signaling

FEBS Open Bio, EarlyView.
Pharmacological inhibition of PERK in a DEN‐induced mouse model of liver cancer does not reduce tumor burden but alters cellular stress signaling. Despite blocking PERK activity, downstream stress responses, including CHOP expression, remain active, suggesting compensatory mechanisms within the unfolded protein response that may influence tumor ...
Ada Lerma‐Clavero, Maria Kopsida, Nathalie Arendt, Hans Lennernäs, Markus Sjöblom, Femke Heindryckx   +5 more
wiley   +1 more source

Macroscopic and microscopic study of integuments on ostrich (Struthio camelus) foot

Journal of Veterinary Research, 2016
Introduction: Ostrich characteristics include fast running, of which the probable enablers have been studied. Yet little research has taken place on one anatomical feature.
Zhang Rui, Ma Songsong, Li Xiujuan, Luo Gang, Xue Shuliang, Li Jianqiao   +5 more
doaj   +1 more source

Determination of macroscopic viscoelastic properties as well as macroscopic thermal deformation and cure-shrinkage properties of fiber reinforced plastics in consideration of cure process

Nihon Kikai Gakkai ronbunshu, 2019
This study presents a method of determining the macroscopic viscoelastic properties as well as the macroscopic coefficients of thermal expansion and cure-shrinkage of fiber-reinforced plastics (FRP) in consideration of the dependence of the viscoelastic ...
Risa SAITO, Yuya YAMAGUCHI, Shuji MORIGUCHI, Yasuko MIHARA, Takaya KOBAYASHI, Kenjiro TERADA   +5 more
doaj   +1 more source

GelMA‐based 3D spheroids recapitulate transcriptomic and functional hallmarks of myeloid sarcoma

FEBS Open Bio, EarlyView.
GelMA 5% hydrogels support the formation of myeloid leukemia spheroids that recapitulate MS‐specific features, including G1 arrest, apoptosis, and ECM‐driven transcriptomic reprogramming. The 3D model mimicked soft‐tissue‐like stiffness and oxygen conditions, and transcriptomic convergence with primary MS samples confirmed its utility as a preclinical ...
Nicolas Germain, Elise Buret, Le Hoang Thanh Nguyen, Marion Cocheteux, Nicolas Touya, Mélanie Dhayer, Romain Dubois, Frank Lafont, Sebastien Janel, Patrice Maboudou, Steve Lancel, Philippe Marchetti   +11 more
wiley   +1 more source

Hematuria in aging men with hemophilia: Association with factor prophylaxis

Research and Practice in Thrombosis and Haemostasis, 2020
Introduction Macroscopic hematuria is considered a significant risk factor for urologic disease, and it is highly prevalent in people with hemophilia. Aim To determine whether prophylactic factor replacement therapy is associated with reduced occurrence ...
Christian Qvigstad, R. Campbell Tait, Philippe deMoerloose, Pål Andre Holme, On behalf of the ADVANCE Working Group   +4 more
doaj   +1 more source

Macroscopic and Microscopic study of thymus of pig

IOSR Journal of Dental and Medical Sciences, 2014
As a preliminary work the macroscopic and macroscopic study of thymus of pig was carried out. 2 male and 2 female pigs weighing 80±10 kgs were used. The thymus of these animals was procured in the slaughter house where it is sacrificed for edible purpose. It was a large bilobed structure situated in the superior mediastinum.
K. Yugesh, Dr. S Swayam Jothi, Dr. K Ranganathan, P. Jayaraman, Chavalin V Bharath, Sujatha N   +5 more
openaire   +1 more source

Five‐Year Outcomes of Laparoscopic Sphincter‐Preserving Surgery for Rectal Cancer: A Prospective Study in Elderly Vietnamese Patients

Aging and Cancer, EarlyView.
This prospective study demonstrates that laparoscopic sphincter‐preserving surgery is feasible for elderly patients. While overall survival reaches 70% at 5 years, advanced T‐stage and the omission of neoadjuvant therapy significantly drive recurrence, highlighting the need for personalized geriatric protocols despite logistical challenges.
Huu Duc Ho, Quang Le, Ngoc Thach Tran, Van Viet Ung, Loc Vu   +4 more
wiley   +1 more source

Evaluation of Healing Potential of Autogenous, Macroscopic Fat Deposited or Fat Free, Omental Graft in Experimental Radius Bone Defect in Rabbit: Radiological Study [PDF]

Pakistan Veterinary Journal, 2011
This study was designed for evaluation of the difference between the ability of greater omentum graft with or without macroscopic fat deposition in acceleration of bone healing process.
Mohammad Nasrollahzadeh Masouleh, Iraj Sohrabi Haghdoost, Gholamreza Abedi Cham Heydari, Amirali Raissi* and Soroush Mohitmafi1
doaj