Results 11 to 20 of about 10,417 (192)

Age-Related Macular Degeneration: What Do We Know So Far?

Acta Medica Lituanica, 2021
Ageing is a natural process that everyone experiences and nobody is an exception. With ageing, our body experiences physiological changes. In this article, the focus is made on the physiological changes of our eyes related to ageing and age-related ...
Ho Hin Ma, Rasa Liutkevičienė
doaj   +1 more source

Coping with the COVID‐19 pandemic by strengthening immunity as a nonpharmaceutical intervention: A major public health challenge

Health Science Reports, Volume 6, Issue 9, September 2023., 2023
Abstract Background and Aims The global Coronavirus‐2 outbreak has emerged as a significant threat to majority of individuals around the world. The most effective solution for addressing this viral outbreak is through vaccination. Simultaneously, the virus's mutation capabilities pose a potential risk to the effectiveness of both vaccines and, in ...
Nizam Uddin, Thamina Acter, Md. Harun‐Ar Rashid, Akibul Islam Chowdhury, Effat Ara Jahan   +4 more
wiley   +1 more source

Compendium of Clinical Variant Classification for 2,246 Unique ABCA4 Variants to Clarify Variant Pathogenicity in Stargardt Disease Using a Modified ACMG/AMP Framework

Human Mutation, Volume 2023, Issue 1, 2023., 2023
Biallelic variants in ABCA4 cause Stargardt disease (STGD1), the most frequent heritable macular disease. Determination of the pathogenicity of variants in ABCA4 proves to be difficult due to (1) the high number of benign and pathogenic variants in the gene; (2) the presence of many rare ABCA4 variants; (3) the presence of complex alleles for which ...
Stéphanie S. Cornelis, Miriam Bauwens, Lonneke Haer-Wigman, Marieke De Bruyne, Madhulatha Pantrangi, Elfride De Baere, Robert B. Hufnagel, Claire-Marie Dhaenens, Frans P. M. Cremers, Jian-Min Chen   +9 more
wiley   +1 more source

Aster la vista: Unraveling the biochemical basis of carotenoid homeostasis in the human retina

BioEssays, Volume 44, Issue 11, November 2022., 2022
Carotenoid pigments play critical roles as colorants, light filters, and chromophores. A novel class of lipid transfer proteins, the Aster proteins (GRAM‐domain containing) were identified. We discuss how the differential expression of Aster proteins and beta‐carotene‐oxygenase 2 (BCO2) establish the unique carotenoid distribution patterns in the ...
Sepalika Bandara, Johannes von Lintig
wiley   +1 more source

Retinal organoids derived from rhesus macaque iPSCs undergo accelerated differentiation compared to human stem cells

Cell Proliferation, Volume 55, Issue 4, April 2022., 2022
Stage 3 rhesus retinal organoids are composed of mature cell types including cone and rod photoreceptors. Abstract Purpose To compare the timing and efficiency of the development of Macaca mulatta, a nonhuman primate (NHP), induced pluripotent stem cell (rhiPSC) derived retinal organoids to those derived from human embryonic stem cells (hESCs ...
Antonio Jacobo Lopez, Sangbae Kim, Xinye Qian, Jeffrey Rogers, J. Timothy Stout, Sara M. Thomasy, Anna La Torre, Rui Chen, Ala Moshiri   +8 more
wiley   +1 more source

[Retracted] The Optos 200Tx Scanning Laser Ophthalmoscope Application in Retinoblastoma Patients’ Follow‐Up

BioMed Research International, Volume 2022, Issue 1, 2022., 2022
Background and Objective. Examination under general anesthesia is the conventional method of follow‐up examination for retinoblastoma (RB) patients. As most of the RB patients are infants or children, general anesthesia for examination often put the children at great risk and affect their growth and development.
Xuehao Cui, Xunda Ji, Yan Shao, Peiquan Zhao, Xiaorong Li, Gaganpreet Kaur   +5 more
wiley   +1 more source

Alterations of retinal thickness measured by optical coherence tomography correlate with neurophysiological measures in diabetic polyneuropathy

Journal of Diabetes Investigation, Volume 12, Issue 8, Page 1430-1441, August 2021., 2021
(1) The thickness of the foveal and parafoveal inner nuclear layer/outer plexiform layer increased in patients with clinical diabetic polyneuropathy compared with patients without clinical diabetic polyneuropathy. (2) A decrease in the thickness of the parafoveal ganglion cell complex correlated with deterioration of nerve functions in the nerve ...
Yuichiro Yamada, Tatsuhito Himeno, Kotaro Tsuboi, Yuka Shibata, Miyuka Kawai, Yuriko Asada‐Yamada, Yusuke Hayashi, Emi Asano‐Hayami, Tomohide Hayami, Yuichiro Ishida, Yohei Ejima, Mikio Motegi, Saeko Asano, Makoto Kato, Eriko Nagao, Hiromi Nakai‐Shimoda, Takahiro Ishikawa, Yoshiaki Morishita, Masaki Kondo, Shin Tsunekawa, Yoshiro Kato, Takayuki Nakayama, Motohiro Kamei, Jiro Nakamura, Hideki Kamiya   +24 more
wiley   +1 more source

Retinal Vascular Changes during the Menstrual Cycle Detected with Optical Coherence Tomography Angiography

Journal of Ophthalmology, Volume 2021, Issue 1, 2021., 2021
Purpose. To evaluate the effects of the menstrual cycle on the retinal vascular status of healthy women by optical coherence tomography angiography (OCTA). Materials and Methods. Healthy women with regular natural menstrual cycles of 28 to 30 days were recruited for this prospective study.
Linning Guo, Chenlei Zhu, Ziqi Wang, Zhiqiang Gao, Zongduan Zhang, Qintuo Pan, Sentaro Kusuhara   +6 more
wiley   +1 more source

Segmentation of Laser Marks of Diabetic Retinopathy in the Fundus Photographs Using Lightweight U‐Net

Journal of Diabetes Research, Volume 2021, Issue 1, 2021., 2021
Diabetic retinopathy (DR) is a prevalent vision‐threatening disease worldwide. Laser marks are the scars left after panretinal photocoagulation, a treatment to prevent patients with severe DR from losing vision. In this study, we develop a deep learning algorithm based on the lightweight U‐Net to segment laser marks from the color fundus photos, which ...
Yukang Jiang, Jianying Pan, Ming Yuan, Yanhe Shen, Jin Zhu, Yishen Wang, Yewei Li, Ke Zhang, Qingyun Yu, Huirui Xie, Huiting Li, Xueqin Wang, Yan Luo, Honghua Yu   +13 more
wiley   +1 more source

NEW METHOD OF OPERATION FOR DETACHMENT OF THE RETINA WITH TEARING OF THE MACULA LUTEA [PDF]

British Journal of Ophthalmology, 1958
exaly   +3 more sources