Results 111 to 120 of about 170,520 (332)

Autosomal Dominant Retinal Dystrophies Caused by a Founder Splice Site Mutation, c.828+3A>T, in PRPH2 and Protein Haplotypes in trans as Modifiers. [PDF]

, 2016
PurposeWe determined the phenotypic variation, disease progression, and potential modifiers of autosomal dominant retinal dystrophies caused by a splice site founder mutation, c.828+3A>T, in the PRPH2 gene.MethodsA total of 62 individuals (19 families)
Birch, David G, Bowne, Sara J, Conneely, Karen N, Daiger, Stephen P, Hughbanks-Wheaton, Dianna K, Shankar, Suma P, Stone, Edwin M, Sullivan, Lori S   +7 more
core  

Global Insights from Patients, Providers, and Staff on Challenges and Solutions in Managing Neovascular Age-Related Macular Degeneration

Ophthalmology and Therapy
Introduction Neovascular age-related macular degeneration is a global public-health concern, associated with a considerable burden to individuals, healthcare systems, and society.
Anat Loewenstein, Michelle Sylvanowicz, Winfried M. Amoaku, Tariq Aslam, Chui Ming Gemmy Cheung, Bora Eldem, Robert P. Finger, Richard P. Gale, Laurent Kodjikian, Adrian Koh, Jean-François Korobelnik, Xiaofeng Lin, Paul Mitchell, Moira Murphy, Mali Okada, Ian Pearce, Francisco J. Rodriguez, Jude Stern, S. James Talks, David T. Wong, Tien Yin Wong, Focke Ziemssen, Jane Barratt   +22 more
doaj   +1 more source

The gut–eye axis: from brain neurodegenerative diseases to age-related macular degeneration

Neural Regeneration Research
Age-related macular degeneration is a serious neurodegenerative disease of the retina that significantly impacts vision. Unfortunately, the specific pathogenesis remains unclear, and effective early treatment options are consequently lacking.
Qianzi Jin, Suyu Wang, Yujia Yao, Qin Jiang, Keran Li   +4 more
doaj   +1 more source

Drug Delivery Technologies for the Treatment of Age-Related Macular Degeneration. [PDF]

Adv Sci (Weinh)
There are multiple therapeutic agents available for the treatment of both dry age‐related macular degeneration (AMD) and wet AMD. It is essential to continue innovation by introducing new drug delivery technologies that can incorporate those along with patient compliance and the accessibility of the technology into the early stages of research and ...
Rodriguez-Cruz JJ, Cutrufello J, Lam M, Nallaparaju S, Peppas NA.   +4 more
europepmc   +2 more sources

Macrophages related to Bruch's membrane in age-related macular degeneration [PDF]

, 1990
Murray C. Killingsworth, J P Sarks, S H Sarks   +2 more
openalex   +1 more source

Integrated Roles of Systemic Diseases and Serum Biomarkers in the Incidence of Age‐Related Macular Degeneration: The UK Biobank Study

Medicine Bulletin, EarlyView.
ABSTRACT Background To evaluate the associations of systemic diseases with AMD incidence and explore whether polygenic risk score (PRS) for AMD influences these associations. To assess the impacts of polymorbidities and serum biomarkers on AMD risk. Methods This prospective study of 471156 AMD‐free UK Biobank participants assessed systemic diseases ...
Jun Yu, Yuzhou Zhang, Mary Ho, Ka Wai Kam, Shi Song Rong, Alvin L. Young, Chi Pui Pang, Clement C. Tham, Jason C. Yam, Li Jia Chen   +9 more
wiley   +1 more source

Early stages of age-related macular degeneration: an immunofluorescence and electron microscopy study. [PDF]

, 1993
Theo L. van der Schaft, Cornelia M. Mooy, W.C. de Bruijn, P T de Jong   +3 more
openalex   +1 more source

Abnormal Serum Lipid Levels and Ocular Metabolic Mediators in Adult‐Onset Myopia: A Cohort Study

Medicine Advances, EarlyView.
Elevated levels of “good cholesterol” markers apolipoprotein A (APOA) and high‐density lipoprotein cholesterol (HDL‐C) were prospectively associated with an increased risk of developing adult‐onset myopia, whereas higher levels of “bad cholesterol” markers apolipoprotein B (APOB) and low‐density lipoprotein cholesterol (LDL‐C) were associated with a ...
Feipeng Jiang, Dawen Wu, Xi Wang, Jier Ma, Xiaohang Chen, Yun Zhang, Chunyan Lei, Jianjun Ren, Longqian Liu, Meixia Zhang   +9 more
wiley   +1 more source

Prevalence of age related macular degeneration in persons aged 50 years and over resident in Australia. [PDF]

, 1993
R. A. Mitchell
openalex   +1 more source

Fine‐Tuning Photochemical Immunogenic Cell Death by a Panel of Verteporfin‐Lipid Nanoparticles: A Data‐Driven Approach

Small Science, EarlyView.
The relationship between the attributes of verteporfin‐lipid nanoparticles and the exposure of immunogenic cell death markers (HSP‐70, HMGB1, and calreticulin) following 690 nm light activation in murine pancreatic cancer cells. Immunogenic cell death (ICD) is an immunostimulatory process that can be induced by light‐activated photosensitizers, but its
Nimit Shah, Maxwell Bortei Quaye, Siddharth Reddy Soma, Meghana Sree Vadlamudi, Doha Mahmoud, Ashritha Malkoochi, Taksheel Rao Aileni, Chanda Bhandari, Kunal Karambelkar, Tayyaba Hasan, Mladen Korbelik, Baowei Fei, Xinxin Song, Girgis Obaid   +13 more
wiley   +1 more source