Results 131 to 140 of about 511,582 (401)

Layered double hydroxides‐based nanozymes for effective biomedical applications: A review and future perspectives

open access: yesBMEMat, EarlyView.
In this review, we introduced the preparation methods of LDHzymes and discussed their catalytic activity and mechanisms. Subsequently, the applications of LDHzymes in biomedical were discussed. Finally, potential future work on LDHzymes was proposed to better design these new types of nanozymes.
Jiawei Cui   +7 more
wiley   +1 more source

The Relationship between Complements and Age-Related Macular Degeneration and Its Pathogenesis

open access: yesJournal of Ophthalmology
Age-related macular degeneration is a retinal disease that causes permanent loss of central vision in people over the age of 65. Its pathogenesis may be related to mitochondrial dysfunction, inflammation, apoptosis, autophagy, complement, intestinal ...
Liyuan Chu   +3 more
doaj   +1 more source

Nanostructured drug delivery systems for posterior segment eye diseases: Strategies to defy ocular barriers

open access: yesBMEMat, EarlyView.
Efficient drug delivery to the posterior segment of the eye has long been a challenging issue due to the complex ocular barriers. The review focuses on the promise held by nanoplatforms for barrier penetration and the key mechanisms involved, also highlighting their advantages in achieving efficient drug delivery and superior treatment of PSEDs ...
Yifan Shen   +7 more
wiley   +1 more source

Prognostic significance of somatic mutations in myeloid cells of men with chronic heart failure – interaction between loss of Y chromosome and clonal haematopoiesis

open access: yesEuropean Journal of Heart Failure, EarlyView.
Abstract Aims Age‐associated clonal haematopoiesis of indeterminate potential (CHIP) has been linked to increased incidence and worse prognosis of chronic heart failure (CHF). CHIP arises from somatic mutations in haematopoietic stem and progenitor cells. Mosaic loss of Y chromosome (LOY), the most common somatic mutation in male blood cells, increases
Sebastian Cremer   +15 more
wiley   +1 more source

Evaluation of an oral telomerase activator for early age-related macular degeneration - a pilot study

open access: yesClinical Ophthalmology, 2016
Coad Thomas Dow,1,2 Calvin B Harley3 1McPherson Eye Research Institute, University of Wisconsin-Madison, Madison, WI, USA; 2Chippewa Valley Eye Clinic, Eau Claire, Wisconsin, WI, USA; 3Independent Telomere Biology Consultant, Murphys, CA, USA Purpose ...
Dow CT, Harley CB
doaj  

Ranibizumab for neovascular age-related macular degeneration.

open access: yesNew England Journal of Medicine, 2006
BACKGROUND Ranibizumab--a recombinant, humanized, monoclonal antibody Fab that neutralizes all active forms of vascular endothelial growth factor A--has been evaluated for the treatment of neovascular age-related macular degeneration.
P. Rosenfeld   +6 more
semanticscholar   +1 more source

Advances in the management of macular degeneration [PDF]

open access: yesF1000Prime Reports, 2014
Current management of age-related macular degeneration (AMD) can be divided into two categories: first, anti-vasoendothelial growth factor (anti-VEGF) injection for wet macular degeneration; second, anti-oxidant vitamins for dry macular degeneration.
openaire   +3 more sources

Peptide redesign for inhibition of the complement system: Targeting age-related macular degeneration. [PDF]

open access: yes, 2016
PurposeTo redesign a complement-inhibiting peptide with the potential to become a therapeutic for dry and wet age-related macular degeneration (AMD).MethodsWe present a new potent peptide (Peptide 2) of the compstatin family.
Cabrera, Andrea P   +6 more
core   +1 more source

Marine Algae‐Derived Bioactives: A Sustainable Resource for the Food and Agriculture Industries

open access: yesFood Frontiers, EarlyView.
Algae are widely used in food and agriculture due to their bioactive compounds and are an eco‐friendly natural preservative and low carbon farming method. However, the problems regarding safety and acceptance still remain as tools like nanotechnology make improvements.
Sara Chadorshabi   +3 more
wiley   +1 more source

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