Results 131 to 140 of about 160,800 (350)

Macular function impairment in eyes with early age-related macular degeneration [PDF]

, 1997
C Degli, Mc Blarzino, M. Valenti, Tatiana Segato, E Mideno   +4 more
openalex   +1 more source

Age‐Associated Decline in Autophagy Pathways in the Retinal Pigment Epithelium and Protective Effects of Topical Trehalose in Light‐Induced Outer Retinal Degeneration in Mice

Aging Cell, EarlyView.
Transcriptomic analyses reveal an age‐related decline in autophagy pathways in RPE/choroid. These pathways remain unchanged in early AMD but become bidirectionally dysregulated in later stages, along with increased RPE loss. Pre‐treatment with trehalose eyedrops enhances RPE autophagy flux and prevents light‐induced outer retinal degeneration in mice ...
Katherine Cox, Gongyu Shi, Neve Read, Mohamed T. Patel, Kepeng Ou, Zijia Liu, Jiahui Wu, Suci Cendanawati, Jenna Le Brun Powell, Pola Goldberg Oppenheimer, Lisa J. Hill, Lindsay B. Nicholson, Andrew D. Dick, Jian Liu   +13 more
wiley   +1 more source

Photodynamic Therapy of Subfoveal Choroidal Neovascularization in Age-related Macular Degeneration With Verteporfin [PDF]

, 1999
Neil M. Bressler
openalex   +1 more source

Rehabilitación óptica en la degeneración macular relativa a la edad Optic rehabilitation in the macular degeneration relative to age

Revista Cubana de Oftalmología, 2002
Se evaluaron 62 pacientes con el diagnóstico de degeneración macular relativa a la edad, desde el mes de septiembre del año 2000 hasta el mes de agosto del año 2001.
Dora Hitchman Barada, Mayra Mier de Armas, Susana Rodríguez Masó   +2 more
doaj  

Hybrid Integent Staging of Age-Related Macular Degeneration for Decision-Making on Patient Management Tactics

Applied Sciences
Treatment efficacy for age-related macular degeneration relies on early diagnosis and precise determination of the disease stage. This involves analyzing biomarkers in retinal images, which can be challenging when handling a large flow of patients and ...
Ekaterina A. Lopukhova, Ernest S. Yusupov, Rada R. Ibragimova, Gulnaz M. Idrisova, Timur R. Mukhamadeev, Elizaveta P. Grakhova, Ruslan V. Kutluyarov   +6 more
doaj   +1 more source

Ythdf2 Ablation Protects Aged Retina From RGC Dendrite Shrinking and Visual Decline

Aging Cell, EarlyView.
The m6A reader YTHDF2 regulates retinal degeneration caused by aging, which is mediated by its target mRNAs Hspa12a and Islr2. ABSTRACT Aging‐related retinal degeneration and vision loss have been severely affecting the elderly worldwide. Previously, we showed that the m6A reader YTHDF2 is a negative regulator for dendrite development and protection of
Fugui Niu, Gaoxin Long, Jian Zhang, Jun Yu, Sheng‐Jian Ji   +4 more
wiley   +1 more source

The Psychosocial Impact of Macular Degeneration [PDF]

, 1998
Rebecca Williams
openalex   +1 more source

Review of Guideline Recommendations for Optimal Anti-VEGF Therapy in Age-Related Macular Degeneration

Life
Neovascular age-related macular degeneration is a progressive, blinding macular disease that has become a burden both in healthcare systems and the global economy. The vascular endothelial growth factor (VEGF) is the main agent involved in the pathogenic
Andreea Dana Moraru, Ciprian Danielescu, Raluca Eugenia Iorga, Radu Lucian Moraru, Mihail Zemba, Daniel Constantin Branisteanu   +5 more
doaj   +1 more source

Prototype master protocol for benchmarking of real‐world follow‐up data in glaucoma

Acta Ophthalmologica, EarlyView.
Abstract Purpose The purpose of this study was to create a prototype master protocol for benchmarking glaucoma real‐world data (RWD). Benchmarking is part of the digital innovation strategy of the Finnish aces‐rwm ecosystem (automation of care and evaluation of the system with real‐world monitoring).
Pekko Hujanen, Anja Tuulonen, Sanna Leinonen, Kristian Vepsäläinen, Gauti Jóhannesson, Anu Vaajanen, Eemil Lehtonen, Hannele Uusitalo‐Jarvinen   +7 more
wiley   +1 more source

Decreased choriocapillaris perfusion following surgical excision of choroidal neovascular membranes in age-related macular degeneration [PDF]

, 1997
Ma'an Nasir, Ikumi Sugino, Marco A. Zarbin   +2 more
openalex   +1 more source