Results 151 to 160 of about 340,047 (304)

Structural retinal changes and visual field loss across timing of damage in children with cerebral visual impairment

Acta Ophthalmologica, EarlyView.
Abstract Purpose To investigate structural changes in the retina and optic nerve head (ONH) of children with cerebral visual impairment (CVI) across different timing of damage (TOD), and to relate these structural changes to visual field (VF) loss severity and pattern.
Jannet Philip, Frouke Nienke Boonstra, Nomdo M. Jansonius   +2 more
wiley   +1 more source

Recent developments in age-related macular degeneration: a review

, 2017
Waseem M Al-Zamil, Sanaa A Yassin Department of Ophthalmology, Imam Abdulrahman Bin Faisal University, Al-Khobar, Saudi Arabia Background: Visual impairment in elderly people is a considerable health problem that significantly affects quality of life ...
Yassin SA, Al-Zamil WM
core  

Occurrence, progression and risk factors of macular atrophy in neovascular age‐related macular degeneration according to neovascularization subtypes

Acta Ophthalmologica, EarlyView.
Abstract Objective To assess the occurrence, risk factors, and progression of macular atrophy (MA) according to macular neovascularization (MNV) subtype in neovascular AMD (nAMD). Methods This multicentre retrospective observational cohort study included 416 eyes with nAMD, followed for at least 12 months and treated with anti‐VEGF.
Amandine Moulin, Geoffrey Zeender, Pauline Rizzuto, Pierre Gascon, Kevin Allaix, Audrey Feldman, Flore De Bats, Benjamin Wolff, Pierre Pradat, Philippe Desmangles, Laurent Kodjikian, Thibaud Mathis   +11 more
wiley   +1 more source

A novel myopathy with autophagic vacuoles associated with biallelic variants in CLN8

Brain Pathology, EarlyView.
We describe a novel adult‐onset myopathy with autophagic vacuoles and characteristic features of ceroid lipofuscinosis associated with biallelic CLN8 variants, seizures, and muscle weakness. Autophagosomal/lysosomal deposition of curvilinear, autofluorescent material containing the mitochondrial adenosine triphosphate (ATP) synthase membrane subunit c ...
Ulrika Lindgren, Carola Hedberg‐Oldfors, Kittichate Visuttijai, Sara Nordström, Hans Goebel, Anders Oldfors   +5 more
wiley   +1 more source

CD93—An emerging vascular target in cancer therapy

British Journal of Pharmacology, EarlyView.
Abstract CD93 is a single‐pass transmembrane glycoprotein that belongs to the C‐type lectin domain group XIV family of proteins. Although it is known to be expressed in other cell types, namely, in some subsets of immune cells, CD93 is primarily expressed on endothelial cells, where it acts as a crucial regulator of angiogenesis.
Beatriz de Alves Pereira, Stefano Barbera, Roberta Lugano, Anna Dimberg   +3 more
wiley   +1 more source

Cerebellar Macular Degeneration

, 1965
Cerebellar macular degeneration in a 7 year old boy with blindness. Rectal biopsy positive for storage material. Nature of cerebral degeneration was not defined in era when picture was taken. Sister also had similar findings. Anatomy: Retina.
William F. Hoyt, MD
core  

Evaluation of the Safety and Therapeutic Range of Nanosecond Laser Treatment in Rabbits

Clinical &Experimental Ophthalmology, EarlyView.
ABSTRACT Background Subthreshold, nanosecond laser therapy has potential as a treatment for age‐related macular degeneration; however, the therapeutic range and safety profile have not been fully documented. In this study, rabbits were used for a preclinical assessment of nanosecond laser treatment.
Glyn Chidlow, John P. M. Wood, Weng Onn Chan, Robert J. Casson   +3 more
wiley   +1 more source

Multivariable Prognostic Models for Age-Related Macular Degeneration: A Systematic Review. [PDF]

J Ophthalmol
Aljied R, Saggu S, Chaudhary V, Pigeyre M, Griffith LE, Raina P.   +5 more
europepmc   +1 more source

The MTRNR2L gene family and age-related macular degeneration. [PDF]

Front Immunol
Moosa A, Wang JJ, DeAngelis MM, Zhang SX.   +3 more
europepmc   +1 more source

Rethinking diabetic retinopathy: Homeostatic mechanisms for retinal clearance

Diabetic Medicine, EarlyView.
In the healthy retina, balanced production and clearance of metabolic waste and fluid maintain retinal homeostasis and normal visual function. Diabetes disrupts this balance, increasing the accumulation of metabolic waste products, including advanced glycation end products (AGEs) and advanced lipoxidation end products (ALEs), while impairing waste and ...
Karis Little, Judith Lechner, Giulia De Rossi, Tara Cullen, Jennifer Perais, Eleni Beli, Noemi Lois, Alan W. Stitt   +7 more
wiley   +1 more source