Results 231 to 240 of about 160,800 (350)

Bilateral MacUlar Degeneration [PDF]

open access: yesProceedings of the Royal Society of Medicine, 1928
openaire   +3 more sources

Loss of 18q Alters TGFβ Signalling Affecting Anteroposterior Neuroectodermal Fate in Human Embryonic Stem Cells

open access: yesCell Proliferation, EarlyView.
hESCsdel18q exhibit delayed and impaired anterior neuroectoderm induction, leading to deficient RPE specification. hESCsdel18q lines showed dysregulation of TGFβ signalling, and endogenous overactivation of activin/nodal/TGFβ in hESCsdel18q leads to improper anterior/posterior neuroectodermal fate commitments.
Yingnan Lei   +9 more
wiley   +1 more source

Chemokine System Changes Drive Age-Related Macular Degeneration and Influence Treatment Outcomes. [PDF]

open access: yesInvest Ophthalmol Vis Sci
Thomsen AK   +6 more
europepmc   +1 more source

PD‐L1 Promotes Immunological Tolerance and Enhances Visual Protection of hESC‐RPE Grafts in Retinal Degeneration

open access: yesCell Proliferation, EarlyView.
We generated immune‐tolerant mature hESC‐RPE cells by overexpressing PD‐L1. PD‐L1‐expressing hESC‐RPE grafts exhibited significantly higher survival, reduced apoptosis and enhanced visual protection in retinal degeneration models, which presents an alternative target to improve the efficiency of hESC‐RPE‐based therapy for AMD. ABSTRACT Immune rejection
Bowen Li   +11 more
wiley   +1 more source

The Prevalence of Age-Related Macular Degeneration and Associated Risk Factors

open access: bronze, 2001
Ronald Klein   +7 more
openalex   +1 more source

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