Results 221 to 230 of about 151,397 (297)

Multi‐Omics Signatures of Organ Clocks in Biological Aging and Disease: A Conceptual Framework for Organ‐Specific Aging Clocks

Aging Cell, Volume 25, Issue 5, May 2026.
Organ‐specific aging clocks integrating genomics, epigenomics, transcriptomics, proteomics, and metabolomics offer a more accurate assessment of biological aging than single‐omics approaches. This review proposes a multi‐omics framework emphasizing tissue data, longitudinal study designs, and clinically meaningful training outcomes to advance the ...
Maria Vasileiou, Gabor Liposits, Bara Barakat, Nam P. Nguyen   +3 more
wiley   +1 more source

Choroidal vascular hyperpermeability patterns in central serous chorioretinopathy correlate with microperimetry: CERTAIN study report 4

Acta Ophthalmologica, Volume 104, Issue 3, Page 288-295, May 2026.
Abstract Purpose This report evaluates the association of three distinct leakage patterns of choroidal vascular hyperpermeability (CVH) on indocyanine green angiography (ICGA), previously correlated with disease chronicity, with retinal sensitivity measured by microperimetry in central serous chorioretinopathy (CSC): unifocal indistinct signs of ...
Jennifer M. Chang‐Wolf, Laurenz J. B. Pauleikhoff, Chabelie Ruiters, Annette C. Moll, Reinier O. Schlingemann, Elon H. C. van Dijk, Roselie M. H. Diederen, Camiel J. F. Boon   +7 more
wiley   +1 more source

Real‐world outcomes of aflibercept 8 mg in patients previously treated for neovascular age‐related macular degeneration

Acta Ophthalmologica, Volume 104, Issue 3, Page 296-304, May 2026.
Abstract Purpose To evaluate visual, anatomical and safety outcomes of aflibercept 8 mg in previously treated patients with neovascular age‐related macular degeneration (nAMD). Methods This retrospective study included nAMD patients switched to aflibercept 8 mg from prior anti‐VEGF therapies at Sahlgrenska University Hospital between February 2024 and ...
Imadeddin Abu Ishkheidem, Esra Inci, Martin Breimer, Sofia Töyrä Silfverswärd, Madeleine Zetterberg, Marita Andersson Grönlund   +5 more
wiley   +1 more source

Phenotyping of Patients with Age-Related Macular Degeneration Using Artificial Intelligence-Driven Biomarker Patterns in OCT. [PDF]

Ophthalmol Sci
Kaufmann A, Blair J, Lasagni Vitar R, Wykoff CC, Cao J, Staurenghi G, Cozzi M, Ciller C, Apostolopoulos S, De Zanet S.   +9 more
europepmc   +1 more source

Fluid/function correlation using AI‐based quantification versus central subfield thickness in treatment‐naïve and pre‐treated patients with neovascular AMD in a real‐world setting

Acta Ophthalmologica, Volume 104, Issue 3, Page 305-313, May 2026.
Abstract Purpose To investigate the association between best‐corrected visual acuity (BCVA) and quantitative macular fluid volumes, compared to central subfield thickness (CST) in treatment‐naïve and previously treated patients with active neovascular age‐related macular degeneration (nAMD).
Anna Eidenberger, Gregor S. Reiter, Virginia Mares, Sophie Frank‐Publig, Philipp Fuchs, Magdalena Baratsits, Markus Gumpinger, Georg Faustmann, Alexandra Miere, Catherine Creuzot‐Garcher, Ulrike Scheschy, Laurent Kodjikian, Vincent Gualino, Benjamin Wolff, Stefan Sacu, Ursula Schmidt‐Erfurth   +15 more
wiley   +1 more source

Volumetric and En Face Hyper-Reflective Henle Fiber Layer in Age-Related Macular Degeneration. [PDF]

Invest Ophthalmol Vis Sci
Wang CX, Wang J, Hormel TT, Hwang TS, Lujan BJ, Bailey ST, Huang D, Jia Y.   +7 more
europepmc   +1 more source

Consensus on age‐related macular degeneration course curricula for general ophthalmologists and non‐ophthalmologist clinical staff: A Delphi study

Acta Ophthalmologica, Volume 104, Issue 3, Page e269-e276, May 2026.
Abstract Purpose To define the curriculum content for two interactive learning courses on age‐related macular degeneration (AMD): (1) an advanced course tailored for general ophthalmologists and (2) a basic course for non‐ophthalmologist healthcare staff.
Filip Sommer‐Lind, Yousif Subhi, Anna S. Vergmann, Monica Lövestam‐Adrian, Nis Andersen, Enrico Borrelli, Lasse J. Cehofski, Mads K. Falk, Øystein K. Jørstad, Kai Kaarniranta, Musa Y. Kaya, Morten B. Larsen, Gregor S. Reiter, Miklos Schneider, Henrik Vorum, Jakob Grauslund, VILMA‐AMD Study Group, Anja Bate, Anja Lund, Anssam Al‐Sharmary, Audrone Rimsaite, Charlotte Melsen, Charlotte Mikkelsen, Christoffer Rud Sørensen, Elizabeth Visby, Hanne Roed, Henrik Kemp, Henrik Melsom, Jeanet Lomholt, Jens Lundgaard Andresen, Jesper Skov, Karen Laursen, Kristian Lundberg, Lena Andersen, Lene Bang Jensen, Line Gerken, Line Petersen, Louise Munkholm, Marie Krogh, Mette Borg Madsen, Mikkel Lyngholm, Per Flesner, Pernille Oversø Hansen, Peter Fahmy, Sathuja Prasad, Søren Berndt Hansen, Søren Kromann Abildgaard   +46 more
wiley   +1 more source

Power and clinical utility of mesopic microperimetry analysis strategies in age‐related macular degeneration

Acta Ophthalmologica, Volume 104, Issue 3, Page e292-e299, May 2026.
Abstract Purpose This study evaluates whether mesopic microperimetry (MMP) provides a more robust measure of retinal function compared to visual acuity (VA) in age‐related macular degeneration (AMD) clinical trials, with a focus on optimal analysis strategies. Method Fellow‐eyes of unilateral neovascular AMD were prospectively studied.
Francesco Cinque, Jeroen Pas, Mahfam Shahabi, Laurens Sluijterman, Sofie ten Brink, Anita de Breuk, Thomas J. Heesterbeek, Caroline Klaver, Carel Hoyng, Yara Lechanteur   +9 more
wiley   +1 more source

Management of fibrosis in neovascular age-related macular degeneration. [PDF]

Graefes Arch Clin Exp Ophthalmol
Chakravarthy U, Foss AJE, Panos GD, Peto T, Rotsos T, Sadda S, De Cock E, Empeslidis T.   +7 more
europepmc   +1 more source

Unique liver function in high myopia: associations with myopic macular degeneration. [PDF]

BMC Ophthalmol
Pei Y, Meng J, He W, Zhang K, Guo D, Lu Y, Zhu X.   +6 more
europepmc   +1 more source