Results 201 to 210 of about 340,047 (304)

HONU: A Multicenter, Prospective, Observational Study of the Progression of Intermediate Age-Related Macular Degeneration. [PDF]

open access: yesOphthalmol Sci
Guymer RH   +15 more
europepmc   +1 more source

Macular telangiectasia type 2 genetic risk variants associated with clinical characteristics in the Slovenian cohort

open access: yesActa Ophthalmologica, Volume 104, Issue 8, Page e982-e992, December 2026.
Abstract Purpose Early diagnosis of macular telangiectasia type 2 (MacTel) remains challenging, and the contribution of genetic variation to its clinical heterogeneity is unclear. This study investigated associations between MacTel risk variants and clinical characteristics in a Slovenian cohort.
Ajda Kunčič   +4 more
wiley   +1 more source

Structural and biochemical basis for retinol‐binding protein 4 antagonism by tinlarebant

open access: yesBritish Journal of Pharmacology, Volume 183, Issue 23, Page 6737-6748, December 2026.
Background and Purpose Retinol‐binding protein 4 (RBP4) is a member of the lipocalin superfamily that is connected to disease states such as insulin resistance, fatty liver disease and ocular disorders including Stargardt disease. Several retinoid and non‐retinoid antagonists of this protein have been developed for potential clinical use, but none have
Marco Bassetto, Philip D. Kiser
wiley   +1 more source

An Atypical Skin Presentation of Adult‐Onset Still's Disease With Histological Description: A Case Report

open access: yesJournal of Cutaneous Pathology, Volume 53, Issue 12, Page 1080-1084, December 2026.
ABSTRACT Adult‐onset Still's disease (AOSD) is an auto inflammatory disorder with a variable clinical presentation, and without a pathognomonic diagnostic test, characterized by high spiking fever, arthralgia/arthritis, a suggestive skin rash, elevated white blood cell count 10 G/L (> 80% neutrophils), elevated ferritin, with glycosylated ferritin < 20%
M. Nordmann   +7 more
wiley   +1 more source

Exploring Endotoxemia in Age-Related Macular Degeneration, Glaucoma, and Diabetic Retinopathy. [PDF]

open access: yesInvest Ophthalmol Vis Sci
Larsen PP   +6 more
europepmc   +1 more source

Multimodal Exploratory Analysis of Persistent Diabetic Macular Edema: Integrating Aqueous Humour Metabolomics, Clinical and OCT Features

open access: yesDiabetes, Obesity and Metabolism, Volume 28, Issue 12, Page 11632-11642, December 2026.
ABSTRACT Purpose This exploratory study integrates aqueous humour metabolomic data with clinical and imaging features to examine candidate biomarkers and characterize multimodal patterns associated with persistent diabetic macular edema (pDME). Methods In this prospective cohort study, DME patients were treated with monthly anti‐VEGF injections over 3 ...
Yunhan Tao   +7 more
wiley   +1 more source

Impact of peripheral optical errors in age-related macular degeneration. [PDF]

open access: yesJ Optom
Venkataraman AP   +6 more
europepmc   +1 more source

Lipid–Polymeric Nanoencapsulation of Standardized Camellia sinensis Extract Enhances Antiangiogenic Activity and Ocular Biocompatibility

open access: yesChemistry &Biodiversity, Volume 23, Issue 11, November 2026.
Workflow for the synthesis, characterization, and biological evaluation of lipid–polymeric nanoparticles loaded with a chemically standardized Camellia sinensis extract, showing improved colloidal stability, ocular biocompatibility, and antiangiogenic activity. Created by the authors using BioRender.com.
Sarah Kelly Fernandes   +7 more
wiley   +1 more source

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