Results 281 to 290 of about 170,520 (332)

Distinct Pathogenic Mechanisms of Neurodegeneration in Pachychoroid Pigment Epitheliopathy Versus Intermediate Age-Related Macular Degeneration. [PDF]

open access: yesOphthalmol Ther
Viggiano P   +13 more
europepmc   +1 more source

Refractive Index‐Corrected Light‐Sheet Microscopy for Macro‐View Cardiovascular Imaging

open access: yesAdvanced Science, Volume 12, Issue 38, October 13, 2025.
A refractive index‐corrected light‐sheet fluorescence microscopy system enables macro‐view cardiovascular imaging across organs, adapting to refractive index variations from different optical clearing protocols. By integrating axial sweeping, multi‐view imaging, and a sealed chamber, it extends the field of view, enhances isotropy, and improves safety.
Enbo Zhu   +13 more
wiley   +1 more source

Plasma Metabolic Profile with Machine Learning Reveals Distinct Diagnostic and Biological Signatures for Pathologic Myopia

open access: yesAdvanced Science, Volume 12, Issue 39, October 20, 2025.
Plasma metabolic detection combined with machine learning offers a precise (area under the curve of 0.874) and high‐throughput (<30 s) diagnosis for pathologic myopia (serious myopic macular degeneration). The biomarkers indicate the pathologic myopia‐associated systemic metabolic reprogramming, which exhibits specificity for myopic macular ...
Ziheng Qi   +13 more
wiley   +1 more source

VEGF in Diabetic Retinopathy and Age-Related Macular Degeneration. [PDF]

open access: yesInt J Mol Sci
Callan A   +5 more
europepmc   +1 more source

Retinal microvascular alterations in Alzheimer's disease: Linking blood plasma biomarkers and cerebral small vessel pathology

open access: yesAlzheimer's &Dementia, Volume 21, Issue 10, October 2025.
Abstract BACKGROUND Retinal microvascular alterations, detectable via color fundus photography (CFP), may reflect cerebral microvascular pathology in Alzheimer's disease (AD). However, their associations with blood‐based biomarkers and cerebral small vessel disease (SVD) remain unclear.
William Robert Kwapong   +16 more
wiley   +1 more source

Impaired Vagal Tone Function-Based Regulation of Systemic Inflammation in Patients With Neovascular Age-Related Macular Degeneration. [PDF]

open access: yesInvest Ophthalmol Vis Sci
Molbech CR   +8 more
europepmc   +1 more source

Mitochondrial Microproteins: Emerging Regulators in Neurodevelopment and Neurodegeneration

open access: yesBioEssays, Volume 47, Issue 10, October 2025.
Mitochondrial microproteins have emerged as critical regulators of mitochondrial function. Neurons are highly dependent on mitochondria to sustain their function. Mitochondrial microproteins can be deregulated and can contribute to the pathogenesis of neurodegenerative disorders. Mitochondrial microproteins are involved in neuronal development. However,
Nada Borghol   +2 more
wiley   +1 more source

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