Results 131 to 140 of about 88,988 (279)
The FASEB Journal, Volume 40, Issue 1, 15 January 2026.Patients with proliferative diabetic retinopathy show elevated vitreous levels of the acrolein adduct FDP‐lys and CCL2. In rat Müller glial cells (TR‐MUL5), acrolein increases Ccl2 gene expression and CCL2 secretion and promotes macrophage migration.
Kanae Fukutsu +4 more
wiley +1 more source
Selective Laser Sintering 3D Printing of Drug‐Loaded Intravitreal Implants
Advanced Functional Materials, Volume 36, Issue 4, 12 January 2026.Selective laser sintering enables the fabrication of biodegradable and biocompatible intravitreal implants with tunable microstructures for sustained drug delivery. By modulating laser scanning speed, the polymer matrix architecture is engineered to control the release kinetics of dexamethasone and riboflavin over several months. This approach offers a
Iria Seoane‐Viaño +5 more
wiley +1 more source
Advanced Science, Volume 13, Issue 1, 5 January 2026.Pathological retinal/choroidal neovascularization drives vision loss in DR and AMD. Current anti‐VEGF injections, while effective, require invasive, frequent administration. Pene/LQ015, is developed a novel topical anti‐VEGFA nanobody formulation achieving therapeutic intraocular levels through penetratin analog‐enhanced delivery.
Chong Chen +12 more
wiley +1 more source
Beyond Treatment: The Strategy of Nonintervention in Choroidal Hemangioma
Clinical Case Reports, Volume 14, Issue 1, January 2026.ABSTRACT The circumscribed choroidal hemangioma (CCH) is a benign congenital eye tumor whose etiology is not clear. A 41‐year‐old female patient came with a 2‐year history of slowly progressive deteriorating vision in her right eye. In the left eye, the best‐corrected visual acuity (BCVA) was 6/6, and counting fingers at 1 m in the right eye.
Humdan Khan +8 more
wiley +1 more source
Baseline Factors Affecting Changes in Diabetic Retinopathy Severity Scale Score After Intravitreal Aflibercept or Laser for Diabetic Macular Edema [PDF]
, 2017 Dilsher S. Dhoot +7 more
openalex +1 more source
Endocrinology, Diabetes &Metabolism, Volume 9, Issue 1, January 2026.Graphical Abstract ABSTRACT Objective Diabetic retinopathy (DR) is characterised by chronic neuroinflammation where the NLRP3 inflammasome plays a pivotal role. This study investigated the therapeutic potential and underlying mechanism of combining systemic metformin (MET) with intravitreal MCC950, a specific NLRP3 inhibitor, in a rodent model of DR ...
Kexuan Ren, Xiaofeng Li
wiley +1 more source
Driving Innovation: The Impact of National Health Policies on Optometry Research in East Asia
The International Journal of Health Planning and Management, Volume 41, Issue 1, Page 37-46, January 2026.ABSTRACT This study examines the optometric research landscape in three East Asian countries—China, Japan, and Korea—analysing how research trends align with each country's national health strategies. By evaluating published articles and reviews from national journals between 2006 March 2025, we identify key areas of focus, including paediatric ...
Jihye Ahn, Moonsung Choi
wiley +1 more source
Intravitreal Aflibercept for the Treatment of Diabetic Macular Edema in Routine Clinical Practice: Results from the 24-Month AURIGA Observational Study [PDF]
, 2023 Simone Donati +10 more
openalex +1 more source
Automatic Segmentation of the Outer and Inner Foveal Avascular Zone by Convolutional Filters
International Journal of Imaging Systems and Technology, Volume 36, Issue 1, January 2026.ABSTRACT In this paper a new algorithm for segmentation of the foveal avascular zone in optical coherence tomography angiography images of the superficial capillary plexus is presented and evaluated. The algorithm is based on convolutional techniques, and for evaluation it has been compared with a collection of manual segmentations.
Carlos Ruiz‐Tabuenca +3 more
wiley +1 more source