Macular edema is a significant cause of vision loss in patients with central retinal vein occlusions and branch retinal vein occlusions. Vascular endothelial growth factor (VEGF) appears to be a key factor in the pathogenesis of this disease.
Lalit Verma+3 more
doaj +1 more source
Intravitreal injection of Ozurdex(®) implant in patients with persistent diabetic macular edema, with six-month follow-up [PDF]
AIM: To evaluate the efficacy of intravitreal dexamethasone injections in diabetic macular edema (DME). METHODS: A 700 μg slow-release intravitreal dexamethasone implant (Ozurdex®) was placed in the vitreal cavity of 17 patients (19 eyes) affected ...
Bottone, A+8 more
core +2 more sources
Diagnostic Criteria for Macular Edema Associated with Venous Occlusions
Background. Macular edema is considered as a risk factor for a significant decrease in the visual acuity and quality of life of the patient, regardless of its cause.
A. G. Shchuko+3 more
doaj +1 more source
Optical coherence tomography fast versus regular macular thickness mapping in diabetic retinopathy [PDF]
Objective: The purpose of the study was to investigate if absolute values and reproducibility of thickness maps obtained from 2 optical coherence tomography (OCT) scanning protocols, regular high-resolution and fast low-density mode, differ in patients ...
Ceklic, Lala+2 more
core +1 more source
A Multiple Stakeholder Multicriteria Decision Analysis in Diabetic Macular Edema Management: The MULTIDEX‑EMD Study [PDF]
Background The clinical and economic management of retinal diseases has become more complex following the introduction of new intravitreal treatments. Multicriteria decision analysis (MCDA) offers the potential to overcome the challenges associated with ...
Casado, Miguel Ángel+19 more
core +3 more sources
Alpha-Lipoic Acid for the Prevention of Diabetic Macular Edema [PDF]
Introduction: To evaluate the effect of alpha-lipoic acid (ALA) on the occurrence of diabetic macular edema. Methods: Randomized, double-blind, placebo-controlled, multicenter, multinational study. Patients were randomized to the treatment group with 600
Anselm Kampik+5 more
core +1 more source
ABSTRACT Background Sphingosine‐1‐phosphate receptor modulators (S1PRM) are used to treat relapsing multiple sclerosis (MS). Each drug has a different S1PR‐subtype selectivity. They target the G‐protein coupled S1P receptors and exert significant immunomodulatory effects, such as preventing the formation of new CNS lesions and the reactivation of pre ...
Faizan Shahzad+8 more
wiley +1 more source
Selective Laser Sintering 3D Printing of Drug‐Loaded Intravitreal Implants
Selective laser sintering enables the fabrication of biodegradable and biocompatible intravitreal implants with tunable microstructures for sustained drug delivery. By modulating laser scanning speed, the polymer matrix architecture is engineered to control the release kinetics of dexamethasone and riboflavin over several months. This approach offers a
Iria Seoane‐Viaño+5 more
wiley +1 more source
Arginine-Restricted Therapy Resistant Bilateral Macular Edema Associated with Gyrate Atrophy
Introduction. Gyrate atrophy is a rare genetical metabolic disorder affecting vision. Here, we report a 9-year-old boy with gyrate atrophy associated with bilateral macular edema at the time of diagnosis and the effect of long term metabolic control on ...
Sibel Doguizi+3 more
doaj +1 more source
Correlation from undiluted vitreous cytokines of untreated central retinal vein occlusion with spectral domain optical coherence tomography [PDF]
Purpose: To correlate inflammatory and proangiogenic key cytokines from undiluted vitreous of treatment-naïve central retinal vein occlusion (CRVO) patients with SD-OCT parameters. Methods: Thirty-five patients (age 71.1 years, 24 phakic, 30 nonischemic)
Cinatl, Jindrich+8 more
core +1 more source