Results 141 to 150 of about 30,963 (261)

Aptamer‐Functionalized Nanocarriers for Bone and Joint Diseases: Engineering Design Rules and Translational Roadmap

Small Science, Volume 6, Issue 5, May 2026.
Aptamer‐functionalized nanocarriers represent a versatile platform for targeted therapy in bone and joint diseases. This review presents five complementary design strategies: free aptamers for soluble targets, bispecific multivalent constructs for enhanced avidity, nanoparticle‐conjugated aptamers for selective tissue accumulation, aptamer‐based ...
Hamdi Al‐Azzani, Djandan Tadum Arthur Vithran, Syeda Sundas Batool, Malek Mohammed Ali Alshabi, Wenhu Zhou, Xiaoqiang Mao   +5 more
wiley   +1 more source

Visual outcome in diabetic retinopathy with macular oedema after combined therapy with intravitreal bevacizumab and retinal photocoagulation: An observational case series

Global Journal of Medicine and Public Health
Purpose To evaluate the Visual Outcome in Diabetic Retinopathy with Macular Oedema after Combined Therapy with Intravitreal Avastin (Bevacizumab) and Retinal Photocoagulation.
Arshi Nazir, Syed T Qureshi, Ejaz Akbar, Andleeb Ahangar, Syed H Kubravi, Tania Sadiq   +5 more
doaj  

Prolonged dengue viremia with predominantly ocular manifestations in a lung transplant recipient

BMC Infectious Diseases
Background The clinical manifestations of dengue are well-described, but ocular involvement is being increasingly recognized and alterations to the natural trajectory of disease, including protracted viraemia, have also been recognized in ...
Leong Shuen Loo, Michael Zhang, Jane Wells, Noor Ali, Ian Marr   +4 more
doaj   +1 more source

Clinical and computed tomography findings of fatal poxviral vasculitis in a domestic shorthair cat

Veterinary Record Case Reports, Volume 14, Issue 2, May 2026.
Abstract This report describes the clinical presentation, haematological abnormalities and imaging findings of systemic poxvirus infection in a cat that resulted in widespread severe dermal oedema and systemic inflammatory response syndrome. The cat lacked cutaneous lesions before the onset of dermal oedema, but developed crusting skin lesions and a ...
Mica Taylor, Harriet R. Hall, Hannah Wong, Lorraine Peschard, Emanuele Ricci, Katie E. McCallum   +5 more
wiley   +1 more source

Dexamethasone tachyphylaxis in the treatment of macular oedema [PDF]

Acta Ophthalmologica, 2013
Parodi, Maurizio Battaglia, Iacono, Pierluigi, Campa, Claudio, La Spina, Carlo, Triolo, Giacinto, Lattanzio, Rosangela, Bandello, Francesco   +6 more
openaire   +2 more sources

Decellularized Aged Bruch's Membrane Confers Unique Biochemical Cues to Retinal Pigment Epithelium for In Vitro Modeling of Age‐Related Macular Degeneration

Aging Cell, Volume 25, Issue 5, May 2026.
A Bruchs membrane (BrM) mimic based on aged decellularized BrM was developed and differentially expressed proteins in aged dECM‐BrM that may provide specific biochemical cues fundamental to model AMD in vitro were identified. RPE culture on aged dECM‐BrM developed certain AMD‐like features including reduced TEER and expression of drusen components ...
Blanca Molins, Mercedes Soledad Nabaes Jodar, Eliandre de Oliveira, Josep Maria Estanyol, Esther Peña, Jaione Bezunartea, María Hernández, Marc Figueras‐Roca, Alfredo Adan   +8 more
wiley   +1 more source

Customizing AI‐based screening with real‐world data: Practical insights from diabetic retinopathy

Acta Ophthalmologica, Volume 104, Issue 3, Page 323-332, May 2026.
Abstract Purpose Diabetic retinopathy (DR) is a leading cause of vision loss in middle‐aged adults globally. Although artificial intelligence (AI)‐based screening tools like IDx‐DR (classification) and Thirona RetCAD (regression) have shown high sensitivity in controlled settings, real‐world screening faces challenges due to missing or low‐quality ...
Broder Poschkamp, Liane Kantz, Petra Augstein, Allam Tayar, Lars Kaderali, Martin Busch, Beathe Bohl, Sebastian Paul, Lisa Lüdtke, Marie‐Christine Bründer, Daniel Schulz, Hanna Grabow, Elke Gens Dipl, Antonia Müller, Emily Martin, Wolfgang Kerner, Jörg Reindel, Andreas Stahl   +17 more
wiley   +1 more source

Estudi tomogràfic dels fotoreceptors de la retina en pacients diabètics sense retinopatia o amb retinopatia no proliferativa lleu [PDF]

, 2016
La retinopatia diabètica (DR) provoca alteracions microvasculars que condueixen a isquemia, alteració de la barrera hematorretiniana, neovascularització i edema macular.
Sanchez Soler, Mireia
core   +1 more source

Characterising PRPF31‐associated retinal dystrophy: Clinical insights from baseline data in a natural history study

Acta Ophthalmologica, Volume 104, Issue 3, Page e317-e328, May 2026.
Abstract Purpose To characterise the baseline clinical features and genotypes of adults with pre‐mRNA processing factor 31 (PRPF31)‐associated retinal dystrophy (RD) enrolled in a prospective, multicentre 4‐year natural history study, and to explore correlations between selected baseline parameters.
Kathrine Olaussen Eriksen, Jon Roger Eidet, Ulrika Kjellström, Jacopo Baldesi, Ragnheidur Bragadóttir, Leonardo Colombo, Josephine Prener Holtan   +6 more
wiley   +1 more source

Neovascular age‐related macular degeneration without drusen

Acta Ophthalmologica, Volume 104, Issue 3, Page e300-e311, May 2026.
Abstract Purpose To describe the clinical characteristics and 1‐year follow‐up of patients with neovascular AMD (nAMD) without drusen in either eye. Methods This is a multicentre retrospective cohort study in three tertiary referral centres in The Netherlands. We included patients of 55 years or older with nAMD in one or both eyes, without the presence
Marc J. Sirks, Elon H. C. van Dijk, Husein Ghalayini, Somayeh Bazdar, WeiFeng Yu, Suzanne Yzer, José P. Martinez Ciriano, Reinier O. Schlingemann, Roselie M. H. Diederen, Camiel J. F. Boon   +9 more
wiley   +1 more source