Results 111 to 120 of about 49,389 (200)

Paramagnetic Rim Lesions Are Associated With Trans‐Synaptic Degeneration of the Visual Pathway in Multiple Sclerosis

open access: yesAnnals of Clinical and Translational Neurology, Volume 13, Issue 9, Page 1831-1841, September 2026.
ABSTRACT Objectives Retrograde trans‐synaptic degeneration (rTSD) from posterior visual pathway lesions in multiple sclerosis (MS) is characterized by hemi‐macular ganglion cell‐inner plexiform layer (GCIPL) thinning and contralateral visual field loss.
Abdul Jaber Tayem   +17 more
wiley   +1 more source

Inhibition of VEGF‐Induced Angiogenesis and Vascular Leakage by Bicistronic Co‐Expression of Aflibercept and COMP‐Ang1

open access: yesAdvanced Healthcare Materials, Volume 15, Issue 35, 18 September 2026.
A bicistronic rAAV8 vector encoding Aflibercept (Afb) and COMP‐cAng1 simultaneously coordinates VEGF clearance and Tie2‐mediated vessel maturation. In a 3D angiogenesis‐on‐a‐chip model, rAAV8‐Afb/cAng1 effectively reverses pathological barrier breakdown under clinical disease‐mimicking challenges.
Bong‐Kyu Kim   +9 more
wiley   +1 more source

Macular thickness profile in an adult population using Spectralis spectral-domain optical coherence tomography. [PDF]

open access: yesSci Rep
Aghamirsalim M   +5 more
europepmc   +1 more source

Photovoltaic Stimulation of Mouse and Pig Retina With Pyrolytic Carbon Microelectrodes Integrated on High‐Density Silicon Solar Cell Arrays

open access: yesAdvanced Healthcare Materials, Volume 15, Issue 36, 25 September 2026.
In this study, we fabricate photovoltaic retinal implants with pyrolytic carbon electrodes and test their ability to stimulate mouse and pig retinas when illuminated with near‐infrared light. We find increased spiking activity in both animal models compared to spontaneous activity and TTX controls and analyze the spike amplitude, latency and frequency.
Akihiro Matsumoto   +10 more
wiley   +1 more source

Enhancing Maturation of Human Neuromuscular Organoids via Electrical Stimulation

open access: yesAdvanced Science, Volume 13, Issue 50, 7 September 2026.
A framework for on‐demand and non‐invasive exposure of human neuromuscular organoids (NMOs) to electrical stimuli is established to promote their maturation. The robustness and effectiveness of different stimulation regimes are evaluated via thorough characterization of organoid tissue structure and contraction capacity. Chronic electrical stimulation,
Chrysanthi‐Maria Moysidou   +12 more
wiley   +1 more source

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