Results 131 to 140 of about 79,007 (279)

Association between metabolic syndrome, macular structures and retinal vascular calibres in the Northern Finland Birth Cohort Eye Study

open access: yesActa Ophthalmologica, EarlyView.
Abstract Purpose We aimed to evaluate the association of metabolic syndrome (MetS) with macular thickness and retinal vascular calibres in the population‐based cohort (Northern Finland Birth Cohort). Methods The population of 2242 individuals was divided into MetS (n = 344) and control groups (n = 1898).
Jenni M. Huru   +4 more
wiley   +1 more source

Interpreting the structure–function relationship in high myopia‐associated glaucoma: A review

open access: yesActa Ophthalmologica, EarlyView.
Abstract Visual field (VF) interpretation in high myopia‐associated glaucoma (HMG) is challenging due to frequent structure–function discordance and coexisting myopia‐related changes. These changes may reduce the reliability of conventional structure–function mapping and increase the risk of misclassifying non‐glaucomatous VF abnormalities as ...
Ruby S. Chan   +6 more
wiley   +1 more source

Adult‐onset Coats disease: A systematic review and meta‐analysis of imaging biomarkers and targeted therapies

open access: yesActa Ophthalmologica, EarlyView.
Abstract Coats disease diagnosed in adulthood is a rare idiopathic retinal telangiectatic vasculopathy that may differ in phenotype from childhood‐diagnosed cases. This systematic review synthesizes current evidence to characterize its clinical spectrum, imaging features, treatment outcomes and underlying mechanisms, with a focus on immunovascular ...
Catarina Francisco   +2 more
wiley   +1 more source

Spontaneous closure of stage IV idiopathic full-thickness macular hole and late reopening as a lamellar macular hole: a case report

open access: yesJournal of Medical Case Reports, 2012
Introduction Spontaneous closure of traumatic macular holes is described as a common event in the peer-reviewed literature. However, the spontaneous closure of stage III and IV full-thickness idiopathic macular holes has been reported in less than 15 ...
Fernández Miriam, Navarro Joaquín
doaj   +1 more source

Junctional sensitivity and atrophy progression rate of geographic atrophy secondary to age‐related macular degeneration

open access: yesActa Ophthalmologica, EarlyView.
Abstract Purpose To determine the relationship between the baseline junctional retinal sensitivity measured with microperimetry and the atrophy progression rate in eyes with geographic atrophy (GA) secondary to age‐related macular degeneration. Methods In this prospective cohort study, patients with GA were examined with fundus autofluorescence (FAF ...
Alexander Kai Thomsen   +5 more
wiley   +1 more source

Corneal transplantation: Restoring sight to the blind

open access: yesActa Ophthalmologica, EarlyView.
Abstract Corneal blindness is one of the leading causes of vision loss worldwide. Transplantation of the cornea can restore vision and make blind patients see again. Corneal transplant surgery has undergone major evolution in recent decades with the advent of minimally invasive lamellar surgical approaches such as DMEK and DALK.
Claus Cursiefen
wiley   +1 more source

New perspectives on VEGF signalling in Alzheimer's disease

open access: yesBrain Pathology, EarlyView.
Emery et al. bring together findings from recent multi‐omic studies, including single‐cell mRNA analysis of human post‐mortem brain tissue, and proteomic analysis of matched CSF and blood samples in large clinical studies. The authors present evidence of the involvement of altered VEGF signalling in vascular and immune dysfunction and neurodegeneration
Cherelle E. G. Emery   +2 more
wiley   +1 more source

A nonhuman primate model of inherited retinal disease. [PDF]

open access: yes, 2019
Inherited retinal degenerations are a common cause of untreatable blindness worldwide, with retinitis pigmentosa and cone dystrophy affecting approximately 1 in 3500 and 1 in 10,000 individuals, respectively.
Artemyev, Nikolai O   +21 more
core  

Twelve‐Month Real‐World Outcomes of Faricimab for Treatment‐Naive Neovascular AMD in Australia

open access: yesClinical &Experimental Ophthalmology, EarlyView.
ABSTRACT Background To provide insights into the effectiveness and safety of faricimab for treatment‐naïve eyes with neovascular age‐related macular degeneration (nAMD). Methods A retrospective cohort study using a prospectively‐designed registry. Treatment‐naïve eyes with nAMD in Australia starting treatment with faricimab between Jan 2023–Sep 2024 ...
Mark Gillies   +8 more
wiley   +1 more source

Measurement of choroidal thickness and macular thickness during and after pregnancy.

open access: yesInternational journal of ophthalmology, 2015
To investigate the effect of pregnancy on subfoveal choroidal thickness (SFCT) and macular thickness in both pregnant and not pregnant healthy women.Twenty-nine healthy pregnant women in their third trimester and 36 age-matched healthy women were enrolled in a prospective, cross-sectional study. Foveal and parafoveal thickness in the four quadrants and
Duru, Z   +5 more
openaire   +3 more sources

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