Results 41 to 50 of about 1,424 (144)

Genotype-phenotype Correlations of Ocular Posterior Segment Abnormalities in Marfan Syndrome

Ophthalmology Science
Purpose: Marfan syndrome (MFS) is a connective tissue disorder caused by mutations in the fibrillin-1 ( (FBN1). In addition to typical phenotypes such as ectopia lentis (EL) and aortic dilation, patients with MFS are prone to ocular posterior segment ...
Yan Liu, BM, Yuqiao Ju, MM, Tian-hui Chen, MM, Yong-xiang Jiang, MD, PhD   +3 more
doaj   +1 more source

Adult‐onset Coats disease: A systematic review and meta‐analysis of imaging biomarkers and targeted therapies

Acta Ophthalmologica, EarlyView.
Abstract Coats disease diagnosed in adulthood is a rare idiopathic retinal telangiectatic vasculopathy that may differ in phenotype from childhood‐diagnosed cases. This systematic review synthesizes current evidence to characterize its clinical spectrum, imaging features, treatment outcomes and underlying mechanisms, with a focus on immunovascular ...
Catarina Francisco, Nisa Silva, Camiel J. F. Boon   +2 more
wiley   +1 more source

Clinical manifestations of dual‐gene variants in retinitis pigmentosa

Acta Ophthalmologica, EarlyView.
Abstract Purpose Retinitis pigmentosa (RP) is an inherited retinal disease (IRD), whereby each affected individual typically harbours pathogenic variants in a single causative gene, yet the disorder exhibits marked genetic heterogeneity, with more than 100 genes reported to underlie RP.
Lasse Wolfram, Jan‐Philipp Bodenbender, David A. Merle, Milda Reith, Anton Sonntag, Krunoslav Stingl, Tobias B. Haack, Theresia Zuleger, Bernd Wissinger, Laura Kühlewein, Katarina Stingl, Susanne Kohl   +11 more
wiley   +1 more source

The sequence of events in six years of a myopic traction maculopathy

GMS Ophthalmology Cases
Purpose: To describe the sequence of events in a case of high myope with myopic traction maculopathy. Methods: Our female patient who is a high myope developed myopic choroidal neovascular membrane (CNVM), for which she received three anti-vascular ...
Baskaran, Prabu, Kariya, Bharg, Rajendran, Anand   +2 more
doaj   +1 more source

IMPG2-Related Maculopathy [PDF]

American Journal of Ophthalmology
To investigate the phenotype, variability, and penetrance of IMPG2-related maculopathy.Retrospective observational case series.Clinical evaluation, multimodal retinal imaging, genetic testing, and molecular modeling.A total of 25 individuals with a mono-allelic IMPG2 variant were included, 5 of whom were relatives of patients with IMPG2-associated ...
Johannes Birtel, Richard Caswell, Samantha R. De Silva, Philipp Herrmann, Salwah Rehman, Andrew J. Lotery, Omar A. Mahroo, Michel Michaelides, Andrew R. Webster, Robert E. MacLaren, Peter Charbel Issa   +10 more
openaire   +4 more sources

En face localization of retinal telangiectatic capillaries using OCT compared with ICG angiography in chronic vascular macular oedema

Acta Ophthalmologica, EarlyView.
Abstract Purpose Retinal telangiectatic capillaries (TelCaps) are microvascular abnormalities associated with chronic vascular macular oedema and suboptimal response to intravitreal therapy. Targeted laser photocoagulation is beneficial but requires precise localization using indocyanine green angiography (ICG‐A), the reference standard. However, ICG‐A
Lucas Unger, Bénédicte Dupas, Mohamed Bennani, Daniela Castro Farias, Jean‐François Girmens, Aude Couturier, Michel Paques, Marie‐Noëlle Delyfer   +7 more
wiley   +1 more source

Spontaneous anatomical and functional recovery of bilateral electric shock maculopathy

Indian Journal of Ophthalmology, 2017
A 12-year-old boy presented with best-corrected visual acuity (BCVA) of 6/9 in both eyes following an episode of electric shock. Optical coherence tomography (OCT) showed disruption of the ellipsoid zone as well as retinal pigment epithelium (RPE) layer.
Ratnesh Ranjan, George Joseph Manayath, Palmeera Dsouza, Venkatapathy Narendran   +3 more
doaj   +1 more source

Retinal dystrophies simulating geographic atrophy: A diagnostic challenge

Acta Ophthalmologica, EarlyView.
Abstract Geographic atrophy (GA) is the chronic loss of retinal pigment epithelium, photoreceptors and choriocapillaris, marking the dry late stage of age‐related macular degeneration (AMD). GA prevalence is expected to rise in the upcoming decades. Advanced GA leads to central scotomas, reducing visual acuity and quality of life, potentially resulting
Johanna M. Colijn, Frank G. Holz, Jeroen Pas, Carel Hoyng   +3 more
wiley   +1 more source

Minimal gauge vitrectomy for optic disc pit maculopathy: Our results

Indian Journal of Ophthalmology, 2015
The purpose of the study was to describe the surgical technique and clinical outcomes of pars plana vitrectomy without laser or gas tamponade in cases with optic disc pit maculopathy at our centre.
Atul Kumar, Varun Gogia, Ritu Nagpal, Sangeeta Roy, Shikha Gupta   +4 more
doaj   +1 more source

Maculopathy: a rare association of the Valsalva manoeuvre (Valsalva maculopathy)

BMJ Case Reports, 2010
A 22-year-old man complained of sudden, painless loss of vision (vague scotoma in central vision) in his right eye. The patient became symptomatic following a session of weight training at a gymnasium the previous day. There was no history trauma. Medical, ocular and familial history were unremarkable.
Sajjad Ahmed, Sheikh, Reyaz Ahmed, Untoo, Imtiaz Ahmed, Lone, Nusrat, Shaheen   +3 more
openaire   +3 more sources