Results 81 to 90 of about 64,270,038 (288)

Gut microbiome and aging—A dynamic interplay of microbes, metabolites, and the immune system

open access: yesFEBS Letters, EarlyView.
Age‐dependent shifts in microbial communities engender shifts in microbial metabolite profiles. These in turn drive shifts in barrier surface permeability of the gut and brain and induce immune activation. When paired with preexisting age‐related chronic inflammation this increases the risk of neuroinflammation and neurodegenerative diseases.
Aaron Mehl, Eran Blacher
wiley   +1 more source

A Pom1 Gradient Is Made to Measure [PDF]

open access: yesJournal of Molecular Cell Biology, 2009
In order for cell division to proceed, fission yeast must first attain critical cell size. The mechanism by which size is detected had not been identified until two recent studies showed that cells utilize an intracellular gradient of Pom1p kinase to measure cell length.
openaire   +2 more sources

Valosin‐containing protein counteracts ATP‐driven dissolution of FUS condensates through its ATPase activity in vitro

open access: yesFEBS Letters, EarlyView.
Biomolecular condensates formed by fused in sarcoma (FUS) are dissolved by high ATP concentrations yet persist in cells. Using a reconstituted system, we demonstrate that valosin‐containing protein (VCP), an AAA+ ATPase, counteracts ATP‐driven dissolution of FUS condensates through its D2 ATPase activity.
Hitomi Kimura   +2 more
wiley   +1 more source

Prawo naturalne fundamentem każdego prawa?

open access: yesAnnales Canonici, 2011
The article discusses the problem articulated in the title, but limiting the realm of discussion to three fields: law made by man, the Divine law, and human rights. First the author made an effort at answering the questions: Does the natural law exist?,
Tomasz Gałkowski
doaj   +1 more source

Made to Measure: Patient-Tailored Treatment of Multiple Sclerosis Using Cell-Based Therapies. [PDF]

open access: yesInt J Mol Sci, 2021
Wens I   +5 more
europepmc   +1 more source

Mobile data: Made to measure [PDF]

open access: yesNature, 2015
Wearable sensors and smartphones are providing a flood of information and empowering population-wide studies.
openaire   +2 more sources

Made to measure? Europeanization, goodness of fit and adaptation pressures in EU competition policy and regional aid

open access: yes, 2006
Increasing attention has been devoted to understanding the process and outcomes of Europeanization, but the measurement of its impact and of the adaptational pressures involved remains elusive. Conventional constructs of Europeanization view 'goodness of
Wishlade, F.G.   +4 more
core   +1 more source

Linking neurogenesis, oligodendrogenesis, and myelination defects to neurodevelopmental disruption in primary mitochondrial disorders

open access: yesFEBS Letters, EarlyView.
Mitochondrial remodeling shapes neural and glial lineage progression by matching metabolic supply with demand. Elevated OXPHOS supports differentiation and myelin formation, while myelin compaction lowers mitochondrial dependence, revealing mitochondria as key drivers of developmental energy adaptation.
Sahitya Ranjan Biswas   +3 more
wiley   +1 more source

Multi-attribute decision-making problem in career determination using single-valued neutrosophic distance measure

open access: yesComplex & Intelligent Systems
In this paper, we introduce a distance measure on single-valued neutrosophic sets by sine function which is a generalization of intuitionistic fuzzy sine distance measure.
M. Arockia Dasan   +3 more
doaj   +1 more source

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