Results 131 to 140 of about 62,455 (285)

Screening of bispecific antibodies during single cell cloning of recombinant Chinese hamster ovary cell lines to improve titer and product quality

open access: yesBiotechnology Progress, EarlyView.
Abstract Development of therapeutic bispecific antibodies (BsAbs) poses significant manufacturability challenges associated with correct chain pairing and an increased diversity of impurities. Here we address this with a product quality assessment during cell line development (CLD), forgoing the need for genetic characterization during cell line ...
Molly Robinson   +7 more
wiley   +1 more source

From Surgical Innovation to Population Impact: Robot‐Assisted Radical Prostatectomy and the Evolution of Surgical Public Health in Brazil's Unified Health System

open access: yesChronic Diseases and Translational Medicine, EarlyView.
ABSTRACT Brazil's Unified Health System (Sistema Único de Saúde, SUS) represents one of the world's largest universal health systems and provides a unique real‐world platform for integrating prevention, diagnosis, treatment, and survivorship across the cancer continuum.
Leonardo Oliveira Reis
wiley   +1 more source

Madness, violence and media

open access: yes, 2019
How are madness and violence represented in media culture? How is a ‘natural’ or ‘causal’ relationship between madness and violence imagined, produced, circulated and resisted in media? This chapter reviews the existing literature on madness and violence
McWade, Brigit
core   +2 more sources

Patients with Chronic Inflammatory Diseases Can Experience Higher Exposure of Small Molecule Drugs than Healthy Volunteers: An Analysis of Recently Approved Drugs

open access: yesClinical Pharmacology &Therapeutics, EarlyView.
Chronic inflammation has long been known to downregulate the activity of certain cytochrome P450 (CYP) enzymes—the main enzymes responsible for the phase I metabolism of many small molecule drugs—potentially leading to higher exposures in patients with chronic inflammatory diseases compared to healthy volunteers. Neglecting this potential difference in
Johannes Tillil   +6 more
wiley   +1 more source

Predicting the Outcomes of NCAA Basketball Championship Games [PDF]

open access: yes
This paper uses the difference in seeding ranks to predict the outcome of March Madness games. It updates the Boulier-Stekler method by predicting the outcomes by rounds. We also use the consensus rankings obtained from individuals, systems and poll.
Andrew Klein, H.O. Stekler
core  

The AI Sustainability Paradox: How Verification and Regulation Synergize to Curb Greenwashing in Emerging Markets

open access: yesCorporate Social Responsibility and Environmental Management, EarlyView.
ABSTRACT Artificial intelligence (AI) reflects a paradox for corporate sustainability: it provides tools for genuine socio‐economic improvement and enables greenwashing at scale. This study examines this duality in emerging Asian markets, where rapid AI adoption coincides with evolving regulatory regimes.
Ashutosh Yadav, Simplice A. Asongu
wiley   +1 more source

Corporate Governance and the Quality of Materiality Assessment Disclosure Under GRI 3: Evidence From Italy

open access: yesCorporate Social Responsibility and Environmental Management, EarlyView.
ABSTRACT This study explores the link between corporate governance and the quality of Materiality Assessment Disclosure (MAD) in sustainability reporting. Based on Agency Theory and the debate over substantive versus symbolic governance, it analyses 138 Italian firms subject to Legislative Decree 254/2016 that published their 2023 Non‐Financial ...
Andrea Bellucci   +2 more
wiley   +1 more source

Madness

open access: yesEmerging Infectious Diseases, 2002
Gerald N. Callahan
doaj   +1 more source

Real‐time multiscale characterization of water migration in deep coal under stepwise pressure‐increasing injection: Combined low‐field nuclear magnetic resonance and multifractal approach

open access: yesDeep Underground Science and Engineering, EarlyView.
The graphical abstract illustrates the real‐time multiscale characterization of water migration in deep coal under stepwise pressure‐increasing injection. Under in‐situ hydrostatic pressure, the water invasion front advances progressively along the axial direction as the injection pressure increases stepwise, tracked in real time by nuclear magnetic ...
Lei Song   +6 more
wiley   +1 more source

Representations of mental health, madness, mental illness and depression in the general population of French Guiana: Similarities and differences between sociodemographic subgroups. [PDF]

open access: yesPLOS Ment Health
Nacher M   +10 more
europepmc   +1 more source

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