Results 31 to 40 of about 1,366,314 (264)
Molecular Oncology, EarlyView.In the present work, we have identified a transcriptional signature based on the differential expression of six genes (BCL2&MAST4, HSH2D&LAT2, METRN&PITPNM2) that would facilitate the early detection of T‐cell acute lymphoblastic leukemia (T‐ALL) patients prone to a poor treatment response and could be implemented at diagnosis, along with other risk ...
Antonio Lahera +11 more
wiley +1 more source
Medicina, médicos y hospitales en el cine de Almodóvar
Revista de Medicina y Cine / Journal of Medicine and Movies, 2022 El presente artículo supone una contribución al tema del título. En él se hace referencia a la obra de Almodóvar en las últimas cuatro décadas como ejemplo y paradigma del cine español, siendo tal vez su director con más éxito público y de crítica, amén ...
Eduardo Alonso Franch
doaj +1 more source
Molecular Oncology, EarlyView.EXOSC10, an essential nuclear RNA exosome‐associated 3′‐5′ exoribonuclease, is inhibited by the anticancer drug 5‐fluorouracil (5‐FU), and EXOSC10 depletion increases 5‐FU sensitivity. The colon‐cancer variant EXOSC10S402T, located in a proteolysis motif, is stable and nuclear but nonfunctional in vivo.
Radhika Sain +10 more
wiley +1 more source
El Futuro del Pasado, 2020 Pese a la riqueza que evidencia en sus análisis locales, la producción historiográfica sobre el Sexenio Democrático presenta vacíos significativos en lo que respecta a la evolución de Madrid.
Santiago De Miguel Salanova
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Molecular Oncology, EarlyView.Intratumour heterogeneity complicates precision management of advanced endometrial cancer. Circulating tumor DNA (ctDNA) offers a minimally invasive strategy to capture tumor evolution and therapeutic resistance. Here, we compare tumor‐agnostic NGS with tumor‐informed ddPCR, outlining their relative sensitivity, concordance, and clinical implications ...
Carlos Casas‐Arozamena +15 more
wiley +1 more source
Mariano Garrigues en Fortuny 14: la casa entre palacios
Veredes, Arquitectura y Divulgación, 2020 En el límite entre el ensanche norte de Madrid y el paseo de la Castellana coexistían, en una misma manzana, tres fincas palaciegas que fueron objeto de varias intervenciones en el tiempo, en la conversión de la Castellana a escenario de poder.
Ismael Amarouch García
doaj
La enseñanza secundaria en Madrid: estudio bibliográfico
Arbor: Ciencia, Pensamiento y Cultura, 2011 En este trabajo se analiza la historiografía sobre la educación secundaria en la Comunidad de Madrid. El análisis se refiere a la época contemporánea (siglos XIX y XX) y se tiene especialmente en cuenta las obras de historiografía publicadas en las ...
Miryam Carreño Rivero +1 more
doaj +1 more source
Molecular Oncology, EarlyView.Both cg12821679MAPRE3 methylation and MAPRE3 expression are significantly associated with overall survival (OS) of non‐small cell lung cancer. Meanwhile, MAPRE3 expression significantly modified the effect of smoking cessation on OS. Smoking cessation benefits OS merely for patients with high MAPRE3 expression.
Chao Chen +14 more
wiley +1 more source
Molecular Oncology, EarlyView.We identify USP29 as the only DUB mirroring CA9 expression, a marker of hypoxia and HIF pathway activation associated with PCA aggressiveness. USP29 stabilizes HIF‐1α and HIF‐2α via a noncanonical mechanism that is independent of PHD/pVHL activity yet relies on proteasomal regulation, establishing USP29 as a previously unrecognized regulator of hypoxic
Amelie S Schober +16 more
wiley +1 more source
Madrid en los años treinta. Ambiente social, político, cultural y religioso / Madrid in the 1930´s. Social, political, cultural and religious situation [PDF]
Studia et Documenta, 2009 The city of Madrid of the 1930’s which witnessed the first steps of Opus Dei was the backdrop for great change. Firstly from the political point of view: the Monarchy had been replaced by the Republic; also the city itself was converted into an urban ...
Julio Montero, Javier Cervera Gil
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