Results 51 to 60 of about 3,387,565 (372)

Unraveling LINE‐1 retrotransposition in head and neck squamous cell carcinoma

open access: yesMolecular Oncology, EarlyView.
The novel RetroTest method allows the detection of L1 activation in clinical samples with low DNA input, providing global L1 activity and the identification of the L1 source element. We applied RetroTest to a real‐world cohort of HNSCC patients where we reported an early L1 activation, with more than 60% of T1 patients showing L1 activity.
Jenifer Brea‐Iglesias   +12 more
wiley   +1 more source

Variance changes detection in multivariate time series [PDF]

open access: yes, 2004
This paper studies the detection of step changes in the variances and in the correlation structure of the components of a vector of time series. Two procedures are considered.
Daniel Peña   +4 more
core   +2 more sources

Hybrid identity and practices to negotiate belonging: Madrid’s Muslim youth of migrant origin

open access: yesComparative Migration Studies, 2020
A qualitative case study of self-identifying Muslim youth of migrant origin in Madrid sought to understand how they formulated identity and employed real cultural practices in navigating belonging. The majority of these youth drew from the so-called “1.5”
C. Boland
semanticscholar   +1 more source

Exploring the role of cyclin D1 in the pathogenesis of multiple myeloma beyond cell cycle regulation

open access: yesMolecular Oncology, EarlyView.
Cyclin D1 overexpression altered the cell adhesion pathway, while cyclin D2 upregulation had less impact on pathway enrichment analysis. Multiple myeloma (MM) patients with cyclin D1 overexpression showed reduced CD56 expression and increased circulating tumor cells (CTC) levels, suggesting that cyclin D1 may contribute to MM cell dissemination ...
Ignacio J. Cardona‐Benavides   +13 more
wiley   +1 more source

Discussing development alternatives for the city of Madrid on the horizon Europe 2020: Challenges and threats from the perspective of knowledge workers

open access: yesAnales de Geografía de la Universidad Complutense, 2013
The Europe 2020 Strategy may show an alternative path to development that Madrid has followed in recent decades and whose contradictions and unbalances are revealed by the bursting of the financial-housing bubble and the economic crisis.
Simón Sánchez Moral
doaj   +1 more source

Replacing the Breit-Wigner amplitude by the complex delta function to describe resonances

open access: yes, 2010
Whenever the Breit-Wigner amplitude appears in a calculation,there are many instances (e.g., Fermi's two-level system and the Weisskopf-Wigner approximation) where energy integrations are extended from the scattering spectrum of the Hamiltonian to the ...
de la Madrid, R.
core   +1 more source

Functional parameters of spermatozoa obtained by a new selection device

open access: yesFEBS Open Bio, EarlyView.
This study compares density gradient centrifugation and the LensHooke CA0™ device for sperm separation. DGC requires multiple steps, specialized equipment, and technical expertise. In contrast, the CA0 device offers key practical and methodological advantages, resulting in a faster, simpler, and more affordable sperm selection method.
Julio C. Chávez   +8 more
wiley   +1 more source

La construcción de la ciudad liberal: Madrid, 1859 y las propuestas de nuevos barrios

open access: yesAnales de Historia del Arte, 2008
The analysis of the four proposals presented to Isabel II by Giraud Daguillon allow for comprehension of the contradictions inherent in the construction of the city in 19th-century Madrid.
Carlos Sambricio
doaj  

Characterization of WAC interactions with R2TP and TTT chaperone complexes linking glucose and glutamine availability to mTORC1 activity

open access: yesFEBS Open Bio, EarlyView.
TTT and R2TP chaperone complexes are required for the assembly and activation of mTORC1. WAC directly interacts with components of TTT, R2TP, and mTORC1, and these interactions are affected by the availability of glucose and glutamine, correlating with changes in mTORC1 activity.
Sofía Cabezudo   +11 more
wiley   +1 more source

The estate of La Zarzuela. New primary sources in its history

open access: yesAnales de Historia del Arte, 2007
Contribution of primary sources for the history of the Royal Site of La Zarzuela from the end of 15th century until 1625, when this agricultural estate was bought by Cardenal Infante Fernando de Austria and then used by his brother, king Felipe IV, as a ...
Mª Ángeles Toajas Roger
doaj  

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