Protoplast-mediated transformation of Madurella mycetomatis using hygromycin resistance as a selection marker. [PDF]
PLoS Neglected Tropical DiseasesMadurella mycetomatis is the main cause of mycetoma, a chronic granulomatous infection for which currently no adequate therapy is available. To improve therapy, more knowledge on a molecular level is required to understand how M.
Saskia du Pré +6 more
doaj +5 more sources
Iron regulatory pathways differentially expressed during Madurella mycetomatis grain development in Galleria mellonella [PDF]
Nature CommunicationsMycetoma is a chronic granulomatous infection of the subcutaneous tissue, most often caused by the fungal pathogen Madurella mycetomatis. Characteristic of the infection is the formation of grains.
Imad Abugessaisa +15 more
doaj +4 more sources
Madurella mycetomatis is highly susceptible to ravuconazole. [PDF]
PLoS Neglected Tropical Diseases, 2014 The current treatment of eumycetoma utilizing ketoconazole is unsatisfactory because of high recurrence rates, which often leads to complications and unnecessary amputations, and its comparatively high cost in endemic areas.
Sarah Abdalla Ahmed +6 more
doaj +9 more sources
Madurella tropicana and Madurella pseudomycetomatis identified as new causative agents of black grain eumycetoma in Senegal [PDF]
Medical Mycology Case ReportsThis study reports Madurella tropicana and Madurella pseudomycetomatis as pathogens causing eumycetoma in Senegal. The dominant species, Madurella mycetomatis, shares morphological features with both.
Maguette Faye +5 more
doaj +5 more sources
Proteomic analysis of the processes leading to Madurella mycetomatis grain formation in Galleria mellonella larvae. [PDF]
PLoS Neglected Tropical Diseases, 2020 Mycetoma is a neglected chronic and granulomatous infection primarily associated with the fungal pathogen Madurella mycetomatis. Characteristic of this infection is the formation of grains. However, the processes leading to grain formation are not known.
Gerard Sheehan +5 more
doaj +4 more sources
Two simultaneous mycetomas caused by Fusarium verticillioides and Madurella mycetomatis [PDF]
Revista do Instituto de Medicina Tropical de São Paulo, 2017 Mycetoma is a chronic granulomatous disease, classified into eumycetoma caused by fungi and actinomycetoma due to aerobic filamentous actinomycetes. Mycetoma can be found in geographic areas near the Tropic of Cancer.
Alexandro Bonifaz +4 more
doaj +6 more sources
Specific and sensitive loop-mediated isothermal amplification (LAMP) method for Madurella strains, eumycetoma filamentous fungi causative agent. [PDF]
PLoS Neglected Tropical Diseases, 2023 BackgroundFilamentous fungi of the genus Madurella are the primary causative agents of mycetoma, a disease observed in tropical and subtropical regions. Since early diagnostics based on a morphological approach are difficult and have many shortcomings, a
Isato Yoshioka +5 more
doaj +5 more sources
Genomics and metagenomics of Madurella mycetomatis, a causative agent of black grain mycetoma in Sudan. [PDF]
PLoS Neglected Tropical Diseases, 2022 Madurella mycetomatis is one of the main causative agents of mycetoma, a debilitating neglected tropical disease. Improved understanding of the genomic diversity of the fungal and bacterial causes of mycetoma is essential to advances in diagnosis and ...
Anastasia P Litvintseva +12 more
doaj +2 more sources
The synthetic synergistic cinnamon oil CIN-102 is active against Madurella mycetomatis, the most common causative agent of mycetoma. [PDF]
PLoS Neglected Tropical Diseases, 2021 Mycetoma is a devastating neglected tropical infection of the subcutaneous tissue and most commonly caused by the fungus Madurella mycetomatis. Treatment of mycetoma consists of a combination of a long term antifungal treatment with itraconazole and ...
Mickey Konings +6 more
doaj +2 more sources
The development of a novel diagnostic PCR for Madurella mycetomatis using a comparative genome approach. [PDF]
PLoS Neglected Tropical Diseases, 2020 BackgroundEumycetoma is a neglected tropical disease most commonly caused by the fungus Madurella mycetomatis. Identification of eumycetoma causative agents can only be reliably performed by molecular identification, most commonly by species-specific PCR.
Wilson Lim +8 more
doaj +2 more sources