Results 71 to 80 of about 1,314 (148)

Direct Extraction and Assessment of Genomic DNA of Mycetoma Fungi from Black-grains Specimen [PDF]

, 2022
Background: Direct isolation of genomic DNA of mycetoma fungi from black-grains achieve rapid diagnosis and may overcome culture disadvantages. Objectives: This study aimed to isolate and assess the DNA of mycetoma fungi using black-grains and to apply ...
Abakar, Adam D, Ahmed, Ahmed E, Ahmed, Elhadi Abdalla, Ahmed, Gamal M. A., Nour, Bakri Y M   +4 more
core   +1 more source

Plant‐Based Mycetoma Inhibitors Targeting the 50S Ribosomal Protein of Nocardia brasiliensis: In Silico Approach

ChemistrySelect, Volume 10, Issue 21, June 4, 2025.
In‐silico drug discovery pipeline for Mycetoma caused by Nocardia brasiliensis. A library of 1034 phytocompounds was screened to identify potent inhibitors, with Parviflorone F showing strong binding and stability against the 50S ribosomal unit. Molecular dynamics confirmed its inhibitory potential, offering a promising therapeutic candidate.
Sandra Jose, Manjunathan Jagadeesan, Meenambiga Setti Sudharsan, Pasiyappazham Ramasamy, Shyamala Gowri, Muthu Thiruvengadam, Sowmya Hari, Baskar Venkidasamy   +7 more
wiley   +1 more source

Analysis of carbohydrates and glycoconjugates by matrix‐assisted laser desorption/ionization mass spectrometry: An update for 2021–2022

Mass Spectrometry Reviews, Volume 44, Issue 3, Page 213-453, May/June 2025.
Abstract The use of matrix‐assisted laser desorption/ionization (MALDI) mass spectrometry for the analysis of carbohydrates and glycoconjugates is a well‐established technique and this review is the 12th update of the original article published in 1999 and brings coverage of the literature to the end of 2022.
David J. Harvey
wiley   +1 more source

The Significance of Mono‐ and Dual‐Effective Agents in the Development of New Antifungal Strategies

Chemical Biology &Drug Design, Volume 105, Issue 1, January 2025.
The future of treating challenging fungal infections lies in novel therapies targeting new antifungal targets, overcoming resistance mechanisms, and exploring innovative dual inhibitors. ABSTRACT Invasive fungal infections (IFIs) pose significant challenges in clinical settings, particularly due to their high morbidity and mortality rates.
Cengiz Zobi, Oztekin Algul
wiley   +1 more source

Addressing the most neglected diseases through an open research model: The discovery of fenarimols as novel drug candidates for eumycetoma. [PDF]

PLoS Neglected Tropical Diseases, 2018
Eumycetoma is a chronic infectious disease characterized by a large subcutaneous mass, often caused by the fungus Madurella mycetomatis. A combination of surgery and prolonged medication is needed to treat this infection with a success rate of only 30 ...
Wilson Lim, Youri Melse, Mickey Konings, Hung Phat Duong, Kimberly Eadie, Benoît Laleu, Benjamin Perry, Matthew H Todd, Jean-Robert Ioset, Wendy W J van de Sande   +9 more
doaj   +1 more source

Photokatalytische CO2 Reduktion mit CO2‐bindenden Enzymen

Angewandte Chemie, Volume 136, Issue 16, April 15, 2024.
Es wird eine neue, vielseitige Aktivität der Phenolsäure‐Decarboxylase aus Bacillus subtilis und anderer CO2‐bindender Enzyme beschrieben. Die Enzyme katalysieren die photokatalytische CO2‐Reduktion in Gegenwart eines Ru(bpy)3‐Photosensibilisators, wobei sie eine hohe Selektivität für die CO2‐Reduktion gegenüber der Protonenreduktion (bis zu 93 ...
Henrik Terholsen, Hilario Diego Huerta‐Zerón, Christina Möller, Henrik Junge, Matthias Beller, Uwe T. Bornscheuer   +5 more
wiley   +1 more source

Genetic variability, antigenicity and antifungal susceptibility of Madurella mycetomatis [PDF]

, 2007
Laureijssen - van de Sande, Wendy
core   +4 more sources

Photocatalytic CO2 Reduction Using CO2‐Binding Enzymes

Angewandte Chemie International Edition, Volume 63, Issue 16, April 15, 2024.
A novel promiscuous activity of the phenolic acid decarboxylase from Bacillus subtilis and other CO2‐binding enzymes is described. The enzymes catalyze the photocatalytic CO2 reduction in the presence of a Ru(bpy)3 photosensitizer, exhibiting high selectivity for CO2 reduction over proton reduction (up to 93 %).
Henrik Terholsen, Hilario Diego Huerta‐Zerón, Christina Möller, Henrik Junge, Matthias Beller, Uwe T. Bornscheuer   +5 more
wiley   +1 more source

Madurella mycetomatisStrains from Mycetoma Lesions in Sudanese Patients Are Clonal [PDF]

Journal of Clinical Microbiology, 2003
ABSTRACTMolecular diversity among clinical isolates ofMadurella mycetomatis, the prime fungal agent of human mycetoma in Sudan, could possibly explain the diverse clinical presentations of this severely debilitating infectious disease. In addition, culture-independent DNA-mediated typing tests need to be developed for this organism, sinceM ...
Ahmed, AOA (Abdalla), Laureijssen - van de Sande, Wendy, Verbrugh, Henri, Fahal, AH, Belkum, Alex   +4 more
openaire   +3 more sources

Using (1,3)‐β‐D‐glucan concentrations in serum to monitor the response of azole therapy in patients with eumycetoma caused by Madurella mycetomatis

Mycoses, Volume 67, Issue 1, January 2024.
Abstract Introduction (1,3)‐β‐D‐glucan is a panfungal biomarker secreted by many fungi, including Madurella mycetomatis, the main causative agent of eumycetoma. Previously we demonstrated that (1,3)‐β‐D‐glucan was present in serum of patients with eumycetoma.
Bertrand Nyuykonge, Emmanuel E. Siddig, Borna A. Nyaoke, Eduard E. Zijlstra, Annelies Verbon, Sahar M. Bakhiet, Ahmed H. Fahal, Wendy W. J. van de Sande   +7 more
wiley   +1 more source