Results 101 to 110 of about 811,172 (335)

CCDC41 Drives Oocyte Meiotic Progression by Promoting Rab11a/Rab7‐Positive Vesicle Fusion with Target Membranes

Advanced Science, EarlyView.
CCDC41 is essential for meiotic maturation in mouse oocytes through regulating Rab7‐positive endosomes fusion with lysosomes and Rab11a‐positive vesicle fusion with the plasma membrane. Abstract Coiled‐coil domain‐containing protein 41 (CCDC41), a core component of centriolar distal appendages involved in centriole assembly and ciliary vesicle docking,
Ying Tian, Jiatong Li, Jingyi Kang, Xiangning Xu, Bicheng Wang, Shuo Lou, Jingyu Li, Yuying Yang, Yanbing Zhang, Yangzi Zheng, Jing Weng, Yuanjing Liang, Wei Ma   +12 more
wiley   +1 more source

Integrated Transcriptomics Reveals Evolutionary Trajectories and Cell Density‐Dependent Mechanisms in Aldosterone‐Producing Adenomas

Advanced Science, EarlyView.
Aldosterone‐producing adenomas (APAs) develop via two distinct paths: directly from adrenal zona glomerulosa (zG) cells, or stepwise from zG cells through aldosterone‐producing micronodules (APMs) before progressing to APAs. Advanced single‐cell and spatial analyses identified distinct cell states linked to oxidative stress and cell–cell interactions ...
Zhuolun Sun, Changying Jing, Martina Tetti, Siyuan Gong, Jia Wei, Yingxian Pang, Martin Reincke, Tracy Ann Williams   +7 more
wiley   +1 more source

Enhancing turn-around-time (TAT) on stroke protocol head CT reports via continuous quality improvement (CQI) methodology in a busy teleradiology practice

American Journal of Experimental and Clinical Research, 2015
Through strict adherence to continuous quality improvement (CQI) methodology, over a 3 year period our teleradiology practice was able to achieve ongoing 100% compliance with our turn-around-time (TAT) goal for interpretation of stroke protocol head CTs.
Stephen Eigles, Sridhar G Panughpath, Arjun Kalyanpur   +2 more
doaj   +2 more sources

Integrating randomized controlled trials and non-randomized studies of interventions to assess the effect of rare events: a Bayesian re-analysis of two meta-analyses

BMC Medical Research Methodology
Background There is a growing trend to include non-randomised studies of interventions (NRSIs) in rare events meta-analyses of randomised controlled trials (RCTs) to complement the evidence from the latter.
Yun Zhou, Minghong Yao, Fan Mei, Yu Ma, Jiayidaer Huan, Kang Zou, Ling Li, Xin Sun   +7 more
doaj   +1 more source

Invited review: “Probiotic” approaches to improving dairy production: Reassessing “magic foo-foo dust”

, 2023
Rim El Jeni, Clothilde Villot, Osman Y. Koyun, Andrea M Osorio-Doblado, J.J. Baloyi, Jeferson M. Lourenço, M.A. Steele, Todd R. Callaway   +7 more
openalex   +1 more source

Neutrophil Extracellular Trap Reprograms Cancer Metabolism to Form a Metastatic Niche Promoting Non‐Small Cell Lung Cancer Brain Metastasis

Advanced Science, EarlyView.
This study mainly combines spatial/single‐cell transcriptomics and metabolomics to reveal LOX+ Malig‐5 as NSCLC brain metastasis‐initiating cells, forming a niche with NET‐releasing neutrophils via the NET‐KRT10 axis. The metastatic niche is involved with metabolic reprogramming, with palmitic acid serving as a key metabolite.
Bo Chen, Karrie M. Kiang, Fangkun Liu, Chuntao Li, Xizhe Li, Chen Weiwei, Xin Fu, Gelei Xiao, Jingyi Sun, Erhan Da, Junbo Liao, Hongshu Zhou, Li Meng, Li Zhou, Tao Song, Longbo Zhang, Gilberto Ka‐Kit Leung, Liyang Zhang   +17 more
wiley   +1 more source

The Cambridge History of Magic and Witchcraft in the West, written by David J. Collins [PDF]

, 2016
Francis Young
openalex   +1 more source

Discovery of a Novel and Potent Kir4.1 Inhibitor as a Safe and Rapid‐Onset Antidepressant Agent in Mice

Advanced Science, EarlyView.
The preferred derivative JX3212 demonstrates strong inhibitory activity against Kir4.1 with favorable druggability and shows significant antidepressant efficacy in vivo. Abstract Major depressive disorder is a serious psychiatric disorder for which novel and fast‐acting antidepressants are required.
Sisi Wang, Xiaoyu Zhou, Mengdan Li, Chao Zhang, Haiyan Xu, Jingyi He, Li Zhan, Yueling Gu, Hao Gu, Tianyu Tu, Hanfang Liu, Taotao Lu, Yueming Zheng, Jian Li, Zhaobing Gao, Yixiang Xu   +15 more
wiley   +1 more source

Integration of non-randomized studies with randomized controlled trials in meta-analyses of clinical studies: a meta-epidemiological study on effect estimation of interventions

BMC Medicine
Backgrounds Syntheses of non-randomized studies of interventions (NRSIs) and randomized controlled trials (RCTs) are increasingly used in decision-making.
Fan Mei, Minghong Yao, Yuning Wang, Jiayidaer Huan, Yu Ma, Guowei Li, Kang Zou, Ling Li, Xin Sun   +8 more
doaj   +1 more source

Innovations in publishing technologies: Enhancing reader experience

Zeszyty Naukowe Wyższej Szkoły Finansów i Prawa w Bielsku-Białej
In this research, the effects that digitalization has had on existing publishing workflows in the context of content creation, circulation and monetization are explored.
Alexey Kalmykov
doaj   +1 more source