Results 61 to 70 of about 765,557 (281)

The resident gut microbiome modulates the effect of synbiotics on the immunogenicity after SARS-COV-2 vaccination in elderly and diabetes patients

npj Biofilms and Microbiomes
The study aims to tackle the seed and soil microbiome and mechanisms that contribute to the effect of synbiotics in enhancing immunogenicity after SARS-CoV-2 vaccination in elderly and diabetic patients. Among 369 subjects who received 3 months of SIM01,
Lin Zhang, Shilan Wang, Martin C. S. Wong, Chris K. P. Mok, Jessica Y. L. Ching, Joyce W. Y. Mak, Chunke Chen, Bing Huo, Shuai Yan, Chun Pan Cheung, Emily O. L. Chiu, Emily Y. T. Fung, Pui Kuan Cheong, Francis K. L. Chan, Siew C. Ng   +14 more
doaj   +1 more source

Gut mycobiome alterations in obesity in geographically different regions

Gut Microbes
The gut fungi play important roles in human health and are involved in energy metabolism. This study aimed to examine gut mycobiome composition in obese subjects in two geographically different regions in China and to identify specific gut fungi ...
Hui Zhan, Yating Wan, Yang Sun, Zhilu Xu, Fen Zhang, Keli Yang, Wenyi Zhu, Chun Pan Cheung, Whitney Tang, Enders Kw Ng, Simon Kh Wong, Yun Kit Yeoh, Francis Kl Chan, Yinglei Miao, Tao Zuo, Zhong Zeng, Siew C Ng   +16 more
doaj   +1 more source

Recent research and developments on wrought magnesium alloys

Journal of Magnesium and Alloys, 2017
Wrought magnesium alloys attract special interests as lightweight structural material due to their homogeneous microstructure and enhanced mechanical properties compared to as-cast alloys. In this contribution, recent research and developments on wrought
Sihang You, Yuanding Huang, Karl Ulrich Kainer, Norbert Hort   +3 more
doaj   +1 more source

Redefining Therapies for Drug‐Resistant Tuberculosis: Synergistic Effects of Antimicrobial Peptides, Nanotechnology, and Computational Design

Advanced Healthcare Materials, EarlyView.
Antimicrobial peptide (AMP)‐loaded nanocarriers provide a multifunctional strategy to combat drug‐resistant Mycobacterium tuberculosis. By enhancing intracellular delivery, bypassing efflux pumps, and disrupting bacterial membranes, this platform restores phagolysosome fusion and macrophage function.
Christian S. Carnero Canales, Jessica Ingrid Marquez Cazorla, Renzo Marianito Marquez Cazorla, Aline Martins dos Santos, Jonatas Lobato Duarte, Letícia Oliveira Catarin Nunes, Túlio Custódio Reis, Lara Cerazi Salvador, Norival Alves Santos‐Filho, Rafael Miguel Sábio, Hélder A. Santos, Fernando Rogério Pavan   +11 more
wiley   +1 more source

Clinicians’ experience with infographic summaries from the BMJ Rapid Recommendations: a qualitative user-testing study among residents and interns at a large teaching hospital in Switzerland

BMJ Open
Objective Clinicians need trustworthy clinical practice guidelines to succeed with evidence-based diagnosis and treatment at the bedside. The BMJ Rapid Recommendations explore innovative ways to enhance dissemination and uptake, including multilayered ...
Thomas Agoritsas, Per Vandvik, Tiffany Hirschel   +2 more
doaj   +1 more source

COVID-19 mRNA vaccine-mediated antibodies in human breast milk and their association with breast milk microbiota composition

npj Vaccines, 2023
Newborns can acquire immunological protection to SARS-CoV-2 through vaccine-conferred antibodies in human breast milk. However, there are some concerns around lactating mothers with regards to potential short- and long-term adverse events and vaccine ...
Shilin Zhao, Kris Y. W. Lok, Zhen Y. Sin, Ye Peng, Heidi S. L. Fan, Nitya Nagesh, Martha S. L. Choi, Jojo Y. Y. Kwok, Edmond P. H. Choi, Xi Zhang, Hogan Kok-Fung Wai, Leo C. H. Tsang, Samuel S. M. Cheng, Matthew K. L. Wong, Jie Zhu, Chris K. P. Mok, Siew C. Ng, Francis K. L. Chan, Malik Peiris, Leo L. M. Poon, Hein M. Tun   +20 more
doaj   +1 more source

A Modular Bioinstructive Platform Reveals Mechanistic Insights into Additive‐Free, Topography‐Driven Osteogenesis

Advanced Healthcare Materials, EarlyView.
Engineered microparticle topographies direct human mesenchymal stem cell osteogenesis without biochemical additives. This osteogenic commitment is driven by canonical Hedgehog signaling and followed by temporal IGF‐II engagement. Two‐photon polymerization demonstrates spatial control, enabling the engineering of topographical gradients that pattern ...
Fatmah I. Ghuloum, Leo A. H. Zeef, Lee A. Stevens, Marco A. N. Domingos, Susan J. Kimber, Mahetab H. Amer   +5 more
wiley   +1 more source

Physics Insights from Recent MAGIC AGN Observations

, 2009
The total set of the 14 active galactic nuclei detected by MAGIC so far includes well-studied bright blazars like Mkn 501, the giant radio galaxy M 87, but also the distant flat-spectrum radio quasar 3C 279, and an intriguing gamma-ray source in the 3C ...
Wagner, Robert
core   +1 more source

Flexible Polypyrrole‐Based pH Sensors via Oxidative Chemical Vapor Deposition

Advanced Healthcare Materials, EarlyView.
Oxidative chemical vapor deposition (oCVD) of polypyrrole (PPy) thin films yields flexible, electrically conductive, and biocompatible pH sensors for monitoring on‐skin biological events. The highly sensitive, oCVD PPy skin‐conformal sensors enable real‐time, spatially resolved sensing of dynamic pH changes within physiologically relevant ranges (4–9 ...
Adrivit Mukherjee, Federico Ferrari, David Garcia Romero, Ilaria Squillante, Job Schoenmaker, Hamoon Hemmatpour, Anton Terpstra, Peter Dijkstra, Julien Es Sayed, L. Jan Anton Koster, Maria Antonietta Loi, Petra Rudolf, Giuseppe Portale, Ajay Giri Prakash Kottapalli, Marleen Kamperman, Ranjita K. Bose   +15 more
wiley   +1 more source

A review of the past and present MAGIC dark matter search program and a glimpse at the future [PDF]

, 2017
The MAGIC TeV gamma-ray telescopes have devoted several hundreds hour of observation time in about a decade, to hunt for particle dark matter indirect signatures in gamma rays, from various candidate targets of interest in the sky: the galactic center ...
Doro, Michele
core   +1 more source