Results 91 to 100 of about 48,287 (295)
Advanced Science, EarlyView.Osteosarcoma stemness is driven by the ITGB2‐COPS3‐SOX2 signaling axis. This study reveals that nuclear COPS3 stabilizes SOX2, which in turn undergoes liquid‐liquid phase separation to promote stemness. Based on this mechanism, a novel COPS3 inhibitor, Z‐5891, was developed, effectively suppressing tumor growth and stemness in vivo, offering a ...
Lei Guo +7 more
wiley +1 more source
Advanced Science, EarlyView.The ER's continuous tubular network is maintained by ER‐shaping proteins whose mutation or dysregulation contributes to neurodegenerative diseases. Here, we show that ER morphology sets the speed of Ca2+ store replenishment between firing events. Disrupting ER continuity slows intra‐ER Ca2+ redistribution from extracellular refill (SOCE) sites, driving
Valentina Davi +13 more
wiley +1 more source
Folk narrative of Mo Yan’s magical realism works - Taking Red Sorghum as an example [PDF]
SHS Web of ConferencesAs the first Chinese Nobel Prize winner in Literature, Mo Yan’s works provide a unique solution for the localization and internationalization of Chinese literature by integrating magical realism with Chinese folk narrative traditions. This article takes
Hu Kexin
doaj +1 more source
Printable Conductive Hydrogels for Electrochemical Biosensing and Soft Bioelectronic Interfaces
Advanced Science, EarlyView.Flexible, conductive hydrogels that integrate printability, mechanical tunability, biocompatibility, and electronic performance remain challenging to achieve. Here, we develop 3D‐printable poly(ethylene glycol)–poly(pyrrole)‐ hydrogels with tissue‐like mechanics, high cytocompatibility, and robust electrochemical function.
Lukas Hein +6 more
wiley +1 more source
The Reading of Mahmoud Darwish's Jidariyya from the Perspective of Magical Realism [PDF]
نقد ادب معاصر عربیIntroduction: Magical Realism has become a place of conflict and discourse challenge between other currents, styles, techniques and genres in understanding its meaning, basis and structure according to the lack of a manifesto.
Sarah Zabihi, Ali Safayi Sangari
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Advanced Science, EarlyView.First‐principles calculations reveal that monolayer In2O${\rm In}_2{\rm O}$ hosts type‐II Dirac fermions near the Fermi level, which split into Weyl points under spin‐orbit coupling. The material exhibits negative and giant magnetoresistance, a pronounced spin Hall effect, and phonon‐mediated superconductivity at 1.5 K, establishing it as a unique ...
Qing‐Bo Liu +6 more
wiley +1 more source
Anatomy and functional characteristics of magical carnivalization in the novel of Peter Jaroš Thousand-year-old bee [PDF]
Slovenska Literatura, 2001 The article considers the function of the elements and procedures of magical camivalisation in the novel Tisícročná včela (A thousend years bee, 1979) by writter Peter Jaroš.
Silvia Pokrivčáková
doaj
RUDN Journal of Studies in Literature and Journalism, 2019 There are many terms that denote the invasion of the inexplicable into a realistic narrative, such as: magical realism, fantastic realism, mystical realism, spiritual realism, transcendental realism, metaphysical realism, Christian realism, etc.
Vitaliy Alexandrovich Gavrikov
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, 2009 Klyachko and coworkers consider an orthogonality graph in the form of a pentagram, and in this way derive a Kochen-Specker inequality for spin 1 systems.
A. Cabello +28 more
core +1 more source
Discovery of a Potent Fluorescence Polarization Probe for Identifying USP1 Allosteric Inhibitors
Advanced Science, EarlyView.This study presents the first ubiquitin‐specific protease 1 (USP1) allosteric fluoroprobe and fluorescence polarization assay, enabling the differentiation of allosteric and catalytic site inhibitors. Further, a novel class of tetrahydroisoquinoline‐based USP1 inhibitors is designed, with compound 14a (USP1 IC50 = 29.9 nM) showing strong selectivity ...
Jiawei Cheng +12 more
wiley +1 more source