Results 171 to 180 of about 1,059,372 (334)
Central Dysmyelination in SSADH‐Deficient Humans and Mice
ABSTRACT Objectives Succinic semialdehyde dehydrogenase deficiency (SSADHD) is an inherited metabolic disorder characterized by an accumulation of γ‐aminobutyric (GABA). In addition to its synaptic role as an inhibitory neurotransmitter, GABA also plays an important role in myelination.
Itay Tokatly Latzer +11 more
wiley +1 more source
Long‐Term Evaluation of Givinostat in Duchenne Muscular Dystrophy, and Natural History Comparisons
ABSTRACT Objectives This ongoing, open‐label extension study is evaluating the long‐term safety, tolerability, and efficacy of givinostat, a Class I and II histone deacetylase inhibitor, in patients with Duchenne muscular dystrophy (DMD). Methods The recruited patients completed one of two prior clinical studies (one Phase 2 and one Phase 3 [EPIDYS ...
Craig M. McDonald +74 more
wiley +1 more source
THE DISSOCIATION OF CALCIUM AND MAGNESIUM PHOSPHATES
Isidor Greenwald +2 more
openalex +1 more source
Ueber die Bestimmung und Trennung des Platins von Kalium, Natrium, Baryum, Strontium, Calcium, Magnesium, Mangan, Wolfram, Kobalt, Nickel, Kupfer, Zink und Cadmium in ammoniakalischer Lösung durch Hydrazin [PDF]
P. Jannasch, Chadi H. Stephan
openalex +1 more source
ABSTRACT Objective Recurrent high‐grade gliomas have a poor prognosis and limited therapeutic options. This study aimed to evaluate the safety and efficacy of SYHA1813, a dual inhibitor of VEGFR and CSF1R, in patients with recurrent high‐grade gliomas.
Zhuang Kang +16 more
wiley +1 more source
Die Trennung des Magnesiums von den Alkalien durch alkoholisches Ammoniumcarbonat [PDF]
F. A. Gooch, E. A. Eddy
openalex +1 more source
Effects of simulated solar radiation on the transmission of magnesium fluoride and cryolite thin films [PDF]
Thin films of cryolite magnesium fluoride on fused silica substrates were exposed to 1126 equivalent sun-hours of radiation. The optical transmissions of the samples were measured before and after irradiation.
Heslin, T.
core +1 more source
Durability of Response to B‐Cell Maturation Antigen‐Directed mRNA Cell Therapy in Myasthenia Gravis
ABSTRACT Objective We report the 12‐month follow‐up outcomes from a Phase 2 clinical trial (NCT04146051) evaluating Descartes‐08, a BCMA‐directed RNA chimeric antigen receptor T‐cell (rCAR‐T) therapy for refractory generalized myasthenia gravis (MG).
Nizar Chahin +10 more
wiley +1 more source

