Results 101 to 110 of about 1,974,494 (302)

Characterization of therapeutic antibodies targeting lymphatic and vascular resistance factor for the treatment of hypervascularized and highly metastatic cancers

Molecular Oncology, EarlyView.
LVRF (lymphatic and vascular resistance factor) is a VEGFA splice variant upregulated in response to anti‐angiogenic therapy that fosters tumor adaptation through enhanced vascularization, lymphangiogenesis, and metastatic dissemination. Targeting LVRF with fully human neutralizing antibodies disrupts these processes and limits resistant tumor growth ...
Marion David, Arthur Karaulic, Audrey Bennetot, Clémence Fournier, Quentin Odet, Arthur Gouraud, Isabelle Bourget, Cédric Gaggioli, Sandy Giuliano, Frédéric Luciano, Olivier Léger, Zaki Sellam, Gilles Pagès   +12 more
wiley   +1 more source

Facile synthesis of azo compounds from aromatic nitro compounds using magnesium and triethylammonium formate

, 2004
Magnesium/triethylammonium formate is a convenient reagent for the reduction of aromatic nitro compounds to corresponding symmetrically substituted azo compounds.
Abiraj, K., Chenne Gowda, D., Srinivasa, G. R.   +2 more
core   +1 more source

Reprogramming tumor cells with LCOR mRNA nanotherapy to enhance immunotherapy

Molecular Oncology, EarlyView.
LCOR (Ligand‐dependent corepressor) mRNA encapsulated in polymeric nanoparticles restores LCOR activity in tumor cells, constraining aggressive tumor cell states and increasing tumor immunogenicity. This reprogramming makes tumor cells more vulnerable to T‐cell attack and enhances their response to immune‐checkpoint immunotherapy.
Gabriel Serra‐Mir, Elena Haro‐Martínez, Sandra Blasco‐Benito, Chiara Cannatà, José Ángel Palomeque, Anna López‐Plana, Maria Sanz‐Flores, Marc Sabartés, Cristina Fornaguera, Toni Celià‐Terrassa   +9 more
wiley   +1 more source

Overcoming platinum resistance by the disulfiram metabolite CuET in novel preclinical models of human carcinomas

Molecular Oncology, EarlyView.
Cisplatin‐resistant cancer cells survive DNA‐damaging platinum‐based treatment yet remain sensitive to CuET‐induced proteotoxic stress. The distinct mechanism of action allows CuET to overcome and eliminate cisplatin‐resistant tumour cells, unless highly expressed metallothioneins (MTs) interfere with CuET, thereby highlighting MT levels as candidate ...
Stefanos Arampatzis, Tereza Buchtová, Jirina Bartkova, Marie Lund Bay, Christoffer Lynge Halvorsen, Zuzana Machacova, Zdenek Skrott, Martin Mistrik, Ekaterina Dulina, Miguel Andujar‐Sanchez, Estrid Høgdall, Tine Henrichsen Schnack, Claus Høgdall, Berit Jul Mosgaard, Marie Boennelycke, Jacob Brink Laursen, Allan Jensen, Susanne K. Kjær, Tuula Kallunki, Robert Strauss, Jiri Bartek   +20 more
wiley   +1 more source

Magnesium-Promoted Additions of Difluoroenolates to Unactivated Imines

, 2018
Although there are many synthetic methods to produce fluorinated and trifluoromethylated organic structures, the construction of difluoromethylated compounds remains a synthetic challenge.
Alex L. Nguyen (1625563), Fronczek, Frank R, Baldwin, Cassidy S, Woods, James R, Frank R. Fronczek, Hari R. Khatri, Khatri, Hari R, David A. Colby, David A. Colby (1944655), Alex L. Nguyen, James R. Woods (4892836), Cassidy S. Baldwin (4892833), Nguyen, Alex L, Cassidy S. Baldwin, Hari R. Khatri (1321710), Colby, David A, James R. Woods, Frank R. Fronczek (568703)   +17 more
core   +1 more source

Process Mechanics and Surface Integrity Induced by Dry and Cryogenic Machining of AZ31B-O Magnesium Alloy [PDF]

, 2013
The corrosion resistance of magnesium alloys depends mainly on its surface integrity. Previous experimental studies have shown that machining can induces small (nano-scale) grain size, compressive residual stresses and basal plane crystallographic ...
GERMAIN, Guénaël, POULACHON, Gerard, G. Germain, BATISTA, Antonio, G. Poulachon, ROSSI, FREDERIC, OUTEIRO, José, G. Fromentin, FROMENTIN, Guillaume, A.C. Batista, F. Rossi, MARTINS DO OUTEIRO, Jose Carlos, J.C. Outeiro   +12 more
core   +1 more source

Raman‐based label‐free microscopic analysis of the pancreas in living zebrafish larvae

FEBS Open Bio, EarlyView.
Forward stimulated Raman scattering (F‐SRS) and epi coherent anti‐Stokes Raman scattering (E‐CARS) allow label‐free discrimination of distinct subcellular structures in the pancreas of living zebrafish larvae. Given the straightforward applicability, we anticipate broad implementation of Raman microscopy in other organs and across various biomedical ...
Noura Faraj, Eline M. F. de Lange, Klaas A. Sjollema, Ben N. G. Giepmans   +3 more
wiley   +1 more source

Tabulation, bibliography, and structure of binary intermetallic compounds. II. Compounds of berylium, magnesium, and calcium [PDF]

, 2013
This is a tabulation, bibliography, and structure of binary intermetallic compounds, including those of berylium, magnesium, and calcium. This report is the second in a series.
Beerntsen, D., Gschneidner, K., Smith, J., Kingston, J., Vest, R.   +4 more
core  

Magnesium and levofloxacin complex compounds composition analysis with ion exchange method [PDF]

, 2020
Magnesium and levofloxacin complex compounds composition analysis with ion exchange methodАнализ состава комплексных соединений магния и левофлоксацина методом ионного ...
Izmozherova, N. V., Бахтин, В. М., Белоконова, Н. А., Rukhmaleva, V. A., Urazaeva, A. T., Beloconova, N. A., Рухмалева, В. А., Уразаева, А. Т., Bakhtin, V. M., Изможерова, Н. В.   +9 more
core  

NANOCOATINGS BASED ON MAGNESIUM COMPOUNDS

Presented research results properties detonation composite nanocoatings based on magnesium orthosilicate under conditions of high-temperature friction at constant load in the sliding velocity field. It has been established that on their surface under conditions of elevated temperatures, stable antifriction structures are formed.
Shchepetov V., Fialko N., Bys S.
openaire   +2 more sources