Results 111 to 120 of about 1,974,494 (302)

UiO‐66 metal–organic frameworks in biomedicine: From structural tunability to bioimaging, photodiagnostics, and photodynamic cancer therapy

FEBS Open Bio, EarlyView.
UiO‐66(Zr) metal–organic frameworks are chemically stable, biocompatible, and highly tunable nanomaterials. Their modular structure enables controlled drug delivery, multimodal bioimaging, and light‐activated photodynamic therapy, supporting integrated diagnostic and therapeutic (theranostic) applications in cancer and biomedical research.
Veronika Huntošová, Grigorii Rakhalskii, Miroslav Almáši   +2 more
wiley   +1 more source

Research progress in effects of Sm on structural and functional properties of magnesium alloys

Cailiao gongcheng
Magnesium alloy is a lightweight metallic material with huge potential for application in automobile， rail transit and aerospace， it can provide a solid support for the green and low-carbon development of China’s manufacturing industry.
LIU Feng, HU Wenxin, YANG Zhenghua, GUO He, HE Wei, WANG Wei   +5 more
doaj   +1 more source

Aquaporin‐3 and aquaporin‐5 impact the development of pancreatic ductal adenocarcinoma spheroids

FEBS Open Bio, EarlyView.
Schematic representation of the role of aquaporin‐3 (AQP3) and aquaporin‐5 (AQP5) in pancreatic ductal adenocarcinoma (PDAC). Both proteins are upregulated in PDAC and are associated with tumor progression and metastatic potential. Silencing AQP3 or AQP5 in PDAC spheroids results in decreased diameter, area, and overall growth, underscoring their key ...
Catarina Pimpão, Diogo M. Engrácia, Graça Soveral, Filipa Mendes   +3 more
wiley   +1 more source

Molecular characterization of covRS mutations in M1UK Streptococcus pyogenes

FEBS Open Bio, EarlyView.
Group A Streptococcus (GAS) acquires covRS mutations driving a hypervirulent bacterial state, frequently associated with invasive disease‐like necrotizing fasciitis. We demonstrate that the newly emerged M1UK GAS lineage can also acquire these mutations.
Jarrad Pritchard, Emma‐Jayne Proctor, Jiawa Wang, Nikolas P. Johnston, Andrew Hayes, Georgia McCorkell, Haibo Yu, Jai Tree, Mark R. Davies, Mark J. Walker, Ronald Sluyter, Stephan Brouwer, Martina L. Sanderson‐Smith   +12 more
wiley   +1 more source

Experimental study on suppression of magnesium powder deflagration flame with different bimetallic supramolecular compounds

Baozha yu Chongji
Magnesium powder, a commonly utilized metallic material, frequently gives rise to combustion and explosion incidents during its production. To identify efficient suppressants for magnesium dust explosions, six bimetallic supramolecular compounds were ...
Huiting WANG, Zhiyue HAN, Ziming YU
doaj   +1 more source

Effects of IGFBP4 deficiency on human preadipocyte proliferation and differentiation through the IGF1R/AKT pathway

FEBS Open Bio, EarlyView.
IGFBP4 knockdown (KD) impairs preadipocyte proliferation and is associated with IGF1R protein downregulation and attenuated AKT phosphorylation. The mechanisms by which IGFBP4 KD influences the IGF1R/AKT signaling pathway involve newly synthesized proteins and lysosomal degradation pathways. Created in BioRender.
Yujia Guo, Sandy Richter, Christoph Bach, Wieland Kiess, Anna Kirstein, Diana Le Duc, Antje Garten   +6 more
wiley   +1 more source

Four- and five-coordinate Magnesium Compounds Containing Ketiminate Ligands. Synthesis and Characterization of L2Mg, L2Mg(LH), and L2Mg(Py), where L = MeC(O)CHC(NAr)Me

, 2012
[[abstract]]Magnesium complexes containing ketiminate ligands were synthesized and characterized. MgBu2 reacted readily in toluene with two equiv. of [MeC(O)CHC(NHAr)Me], where Ar = 2,6-diisopropylphenyl, to generate [MeC(O)CHC(NAr)Me]2Mg (1) in 43 ...
Lee, Wen-Yi; Hsieh, Hsiang-Hua; Hsieh, Chun-Chin; Lee, Hon-Man; Lee, Gene-Hsiang; Huang, Jui-Hsien; Wu, Tsun-Cheng; Chuang, Shiow-Huey
core  

Solvent-free synthesis of dihydropyrano [3,2-c]chromene and biscoumarin derivatives using magnesium oxide nanoparticles as a recyclable catalyst

Acta Chimica Slovenica, 2014
In these research, an efficient one pot approach for the synthesis of dihydropyrano[3,2-c]chromenes and biscoumarins as important heterocyclic compounds with pharmacological and biological properties have been prepared using nanocrystalline magnesium ...
Javad Safaei-Ghomi, Fahime Eshteghal, Mohammad Ali Ghasemzadeh   +2 more
doaj  

From energy provision to protein synthesis: Tunnelling nanotubes as mediators of intercellular metabolic cooperation in cancer

FEBS Open Bio, EarlyView.
The cytoskeleton‐mediated transport of mitochondria via tunnelling nanotubes restores respiration, increases ATP production, rescues cells from apoptosis, activates the AKT/mTOR signalling pathway, promotes cell migration and invasiveness, contributes to cancer progression and treatment resistance.
Stanislava Martínková, Jan Trnka
wiley   +1 more source

Treatment with KCL‐286, a first‐in‐class retinoic acid receptor‐β (RARβ) agonist, ameliorates neuronal DNA damage and inflammation in a mouse model of Alzheimer's disease

FEBS Open Bio, EarlyView.
Repair of neuronal DNA damage in Alzheimer's disease by KCL‐286. (A) Amyloid‐β oligomers and plaques impair neuronal DNA repair pathways, leading to DNA double‐strand breaks and glial activation. (B) KCL‐286 activates RARβ/RXR signalling via retinoic acid response elements (RAREs), associated with increased BRCA1 expression, enhanced DNA repair and ...
Natasha Hill, Hassan Yousef Othman AlMuallim, Elouisa Maddock, Carl Hobbs, Earl Clarke, Maria B. Goncalves, Jonathan P. T. Corcoran   +6 more
wiley   +1 more source