Results 91 to 100 of about 51,881 (309)
Potential therapeutic targeting of BKCa channels in glioblastoma treatment
This review summarizes current insights into the role of BKCa and mitoBKCa channels in glioblastoma biology, their potential classification as oncochannels, and the emerging pharmacological strategies targeting these channels, emphasizing the translational challenges in developing BKCa‐directed therapies for glioblastoma treatment.
Kamila Maliszewska‐Olejniczak +4 more
wiley +1 more source
Effect of added magnesium, potassium, lime and nitrogen on oats: I. Yields
With peat as the growth base the effect of the various combinations of three amounts of magnesium, of three of potassium, of two of lime and two of nitrogen on the grain and the straw crop yields, grown in pots, was investigated. During three seasons the
Raili Jokinen
doaj
Effective therapeutic targeting of CTNNB1‐mutant hepatoblastoma with WNTinib
WNTinib, a Wnt/CTNNB1 inhibitor, was tested in hepatoblastoma (HB) experimental models. It delayed tumor growth and improved survival in CTNNB1‐mutant in vivo models. In organoids, WNTinib outperformed cisplatin and showed enhanced efficacy in combination therapy, supporting its potential as a targeted treatment for CTNNB1‐mutated HB.
Ugne Balaseviciute +17 more
wiley +1 more source
Nutritional Disorders of Grain Sorghum [PDF]
Crop Production/Industries,
Asher, Colin J. +4 more
core +1 more source
The LINC01116 long noncoding RNA is induced by hypoxia and associated with poor prognosis and high recurrence rates in two cohorts of lung adenocarcinoma patients. Here, we demonstrate that besides its expression in cancer cells, LINC01116 is markedly expressed in lymphatic endothelial cells of the tumor stroma in which it participates in hypoxia ...
Marine Gautier‐Isola +12 more
wiley +1 more source
Plants dynamically respond to varying light intensities, which may further interact with their nutrient status to affect gas exchange parameters. This study investigated the combined effect of instantaneous light intensity and magnesium suppression on ...
Lucas Aparecido Manzani Lisboa +3 more
doaj +1 more source
Plants produce strigolactones (SLs) in roots in response to nitrogen or phosphate deficiency. To evaluate SL levels under other mineral deficiencies in rice, we cultivated rice seedlings in hydroponic media without nitrogen, phosphorus, potassium, sulfur,
Masato Shindo +3 more
doaj +1 more source
Freshwater biology and water supply in Britain [PDF]
This paper is designed to give a general account of freshwater biology as it bears on waterworks practice. Most water that is used for consumption will commonly go through a storage reservoir.
Gardiner, A.C. +2 more
core
Plecstatin inhibits hepatocellular carcinoma tumorigenesis and invasion through cytolinker plectin
The ruthenium‐based metallodrug plecstatin exerts its anticancer effect in hepatocellular carcinoma (HCC) primarily through selective targeting of plectin. By disrupting plectin‐mediated cytoskeletal organization, plecstatin inhibits anchorage‐dependent growth, cell polarization, and tumor cell dissemination.
Zuzana Outla +10 more
wiley +1 more source
Background Magnesium (Mg)-deficiency occurs most frequently in strongly acidic, sandy soils. Citrus are grown mainly on acidic and strong acidic soils. Mg-deficiency causes poor fruit quality and low fruit yield in some Citrus orchards.
Wei-Wei Liang +6 more
doaj +1 more source

