Results 111 to 120 of about 22,586 (294)
Abstract Defining the CSF cytokine/chemokine and injury biomarker signature of glial fibrillary acidic protein (GFAP) autoimmunity can inform immunopathogenesis. CSF GFAP‐IgG‐positive samples (N = 98) were tested for 17 cytokines/chemokines, neurofilament light chain (NfL), and GFAP (ELLA, Bio‐Techne).
Yahel Segal+11 more
wiley +1 more source
Host Tree Identity Influences Leaf Nutrient Relations of the Epiphyte Dendrobium guamense Ames.
Epiphytic orchid species grow in stressful conditions that include nutrient deficiency. A greater understanding of the factors that influence epiphytic orchid nutrition may benefit conservationists and horticulturists.
Thomas E. Marler
doaj +1 more source
Handling rescue therapy in myasthenia gravis clinical trials: why it matters and why you should care
Abstract Myasthenia gravis (MG) clinical trials typically allow rescue therapy during follow‐up in the event of marked worsening of MG symptoms. Failure to appropriately address rescue therapy in defining treatment effects and planning statistical analyses may yield biased estimates, increase false positive rates, or decrease statistical power – all of
Justin M. Leach+3 more
wiley +1 more source
ALS plasma biomarkers reveal neurofilament and pTau correlate with disease onset and progression
Abstract Objective We performed a pilot screen to assess the utility of the NULISA™ (Nucleic‐acid‐Linked Immuno‐Sandwich Assay) platform in the identification of amyotrophic lateral sclerosis (ALS) biomarkers. Methods Plasma from 86 individuals (48 ALS, 18 asymptomatic C9orf72 repeat expansion carriers (AsymC9), and 20 healthy controls) was analyzed ...
Eleanor V. Thomas+10 more
wiley +1 more source
Plants wouldn't be green without magnesium : Magnesium deficiency: Yellowing of leaf between veins
Heuvelink, E., Kierkels, Tijs
openaire +2 more sources
Amygdala Neurodegeneration: A Key Driver of Visual Dysfunction in Parkinson's Disease
ABSTRACT Objective Visual disability in Parkinson's disease (PD) is not fully explained by retinal neurodegeneration. We aimed to delineate the brain substrate of visual dysfunction in PD and its association with retinal thickness. Methods Forty‐two PD patients and 29 controls underwent 3‐Tesla MRI, retinal spectral‐domain optical coherence tomography,
Asier Erramuzpe+15 more
wiley +1 more source
ABSTRACT Febrile infection related epilepsy syndrome (FIRES) is a rare presentation of refractory status epilepticus with immune dysregulation as a potential pathologic mechanism. Despite promising results from second‐line immunomodulators, approximately 30% remain refractory to treatment.
Kristen S. Fisher+5 more
wiley +1 more source
H1504+65 - The Naked Stellar C/O Core of a Former Red Giant Observed with FUSE and Chandra [PDF]
H1504+65 is an extremely hot hydrogen-deficient white dwarf with an effective temperature close to 200,000 K. We present new FUV and soft X-ray spectra obtained with FUSE and Chandra, which confirm that H1504+65 has an atmosphere primarily composed of carbon and oxygen.
arxiv
Longitudinal Trajectories of Digital Cognitive Biomarkers for Multiple Sclerosis
ABSTRACT Background Cognitive impairment is one of the most common and debilitating symptoms of relapsing–remitting multiple sclerosis (RRMS). Digital cognitive biomarkers require less time and resources and are rapidly gaining popularity in clinical settings.
Yi Chao Foong+17 more
wiley +1 more source
ABSTRACT C‐truncating variants in the charged multivesicular body protein 2B (CHMP2B) gene are a rare cause of frontotemporal lobar degeneration (FTLD), previously identified only in Denmark, Belgium, and China. We report a novel CHMP2B splice‐site variant (c.35‐1G>A) associated with familial FTLD in Spain. The cases were two monozygotic male twins who
Sara Rubio‐Guerra+17 more
wiley +1 more source