This PROSPERO‐registered review analysed 37 RCTs on neuronutraceuticals for Alzheimer's disease. Despite diverse targets—amyloid/tau, inflammation, oxidative stress, metabolism, synaptic plasticity, cholinergic and hormonal—the evidence was of low quality. RoB2 flagged attrition (86.5%) and reporting bias (81%). Current data do not support clinical use;
Mehmet Akif Topcuoglu, Esen Saka
wiley +1 more source
Longterm experience of magnerot administration in patients with mitral valve prolapse
Within 15 years observation 31 patients with prolaps the mitral valve, regularly accepting magnerot, in a dose of 1500 mg a day during all period of observation by 3-month's courses 2 times a year was spent.
A. I. Martynov, E. V. Akatova
doaj +1 more source
The role of magnesium in the genesis and prevention of miscarriage
Miscarriage is contributed by a number of different factors; among those, magnesium deficiency has a specific mechanism and polypathogenic effects. According to the results of numerous studies, magnesium medicines are effective in complex therapy of ...
A. L. Unanyan +8 more
doaj +1 more source
This graphical abstract illustrates the effects of myo‐inositol supplementation during suckling in reducing long‐term metabolic impacts from mild gestational calorie restriction (GCR). Using a metabolomics approach, 164 metabolites were identified, with greater metabolic alterations in males.
Rocío A. Martín‐Chamorro +6 more
wiley +1 more source
The Concise Guide to PHARMACOLOGY 2025/26: Enzymes
The Concise Guide to Pharmacology 2025/26 marks the seventh edition in this series of biennial publications in the British Journal of Pharmacology. Presented in landscape format, the guide provides a comparative overview of the pharmacology of drug target families. The concise nature of the Concise Guide refers to the style of presentation, being clear,
Stephen P. H. Alexander +31 more
wiley +1 more source
Clinico-economic evaluation of complex cardiovascular therapy with magnesium orotate in patients with chronic heart failure versus standard therapy in Ukraine [PDF]
OBJECTIVES: To evaluate the profitability of the complex cardiovascular therapy with magnesium orotate in patients with chronic heart failure (CHF) IV functional class (NYHA IV).
Iakovlieva, L. +2 more
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Characterization of the Fecal Metabolome in Patients With Early Systemic Sclerosis
Objective To evaluate the fecal metabolome in patients with early systemic sclerosis (SSc) compared with unaffected controls and to determine if altered metabolites are associated with specific bacterial genera in patients with early SSc. Methods Stool samples and clinical data were collected from 106 patients with early SSc and 79 unaffected control ...
Arissa C. Young +6 more
wiley +1 more source
A comparative study of the effectiveness of magnesium orotate tautomers to com-pensate magnesium deficiency. Part I. The influence of magnesium orotate tautomers on laboratory animals and humans isolated cells [PDF]
The objects of the research were erythrocytes and lymphocytes of humans and rats and human buccal epitheliocites. The hemolysis of erythrocytes and microelectrophoresic cell mobility in solutions of saline with the orotate magnesium tautomers was studied.
Kanunnikov, M. M. +9 more
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Lithium Augmentation in Treatment‐Resistant Depression: A Qualitative Review of the Literature
ABSTRACT Depression is the leading cause of disability worldwide, affecting people of all ages. Both pharmacological and non‐pharmacological therapies are available for its treatment. However, some patients do not respond to first‐line pharmacological interventions, referred to as treatment‐resistant depression (TRD).
Angela Acero‐González +8 more
wiley +1 more source
A comparative study of the effectiveness of magnesium orotate tautomers to compen-sate magnesium deficiency. II. The influence of oxo – and hydroxyforms of magnesium orotate on laboratory animals blood and tissues elemental composition [PDF]
Under fusemide-induced hypomagnesemia in animals, the hydroxy form of magnesium orotate shows a higher rate of compensation for magnesium deficiency in the blood compared to the oxo form.
Aksenova, V. V. +11 more
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