An Investigation on the Efficacy of Orotic Acid as a Bio-Nucleating Agent for Poly-Lactic Acid under Quiescent Condition and Injection Molding [PDF]
Micromachines, 2022 Polylactic acid (PLA) is a bio-based biodegradable polymer and is considered to be an environmentally friendly alternative to petroleum-based polymers for various applications.
Peng Gao +3 more
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A Facile Fluorometric Assay of Orotate Phosphoribosyltransferase Activity Using a Selective Fluorogenic Reaction for Orotic Acid [PDF]
Sensors, 2023 Orotate phosphoribosyltransferase (OPRT) exists as a bifunctional enzyme, uridine 5′-monophosphate synthase, in mammalian cells and plays an important role in pyrimidine biosynthesis.
Takayuki Shibata +4 more
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Effects of Cyclic High Ambient Temperature and Dietary Supplementation of Orotic Acid, a Pyrimidine Precursor, on Plasma and Muscle Metabolites in Broiler Chickens [PDF]
Metabolites, 2020 The aim of this study was to evaluate the effects of high ambient temperature (HT) and orotic acid supplementation on the plasma and muscle metabolomic profiles in broiler chickens.
Saki Shimamoto +5 more
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Redetermination of orotic acid monohydrate [PDF]
Acta Crystallographica Section E, 2008 The crystal structure of the title compound, which is also known as vitamin B13 (systematic name: 2,6-dioxo-1,2,3,6-tetrahydropyrimidine-4-carboxylic acid monohydrate), C5H4N2O4·H2O, was reported for the first time by Takusagawa & Shimada [Bull ...
Gustavo Portalone
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The Improved Method for Determination of Orotic Acid in Milk by Ultra-Fast Liquid Chromatography with Optimized Photodiode Array Detection [PDF]
Animals, 2021 Ultra-fast liquid chromatography (UFLC) with a photodiode array detector (DAD) for simple and rapid determination of orotic acid (OAc) in milk of sheep and cows is described. Milk samples are treated with acetonitrile (1:1, v/v) and then centrifuged at 4
Marian Czauderna +3 more
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Orotic acid-treated hepatocellular carcinoma cells resist steatosis by modification of fatty acid metabolism [PDF]
Lipids in Health and Disease, 2020 Background Orotic acid (OA) has been intensively utilized to induce fatty liver in rats. Although the capacity of OA to cause steatosis is species-specific, previous in vitro studies indicate that humans could also be susceptible to OA-induced fatty ...
Johanna Matilainen +5 more
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Photodegradation and Biodegradation of Poly(Lactic) Acid Containing Orotic Acid as a Nucleation Agent. [PDF]
Materials (Basel), 2019 Salač J +5 more
europepmc +2 more sources
Hereditary orotic aciduria identified by newborn screening
Frontiers in Genetics, 2023 Introduction: Hereditary orotic aciduria is an extremely rare, autosomal recessive disease caused by deficiency of uridine monophosphate synthase.
Orna Staretz-Chacham +38 more
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Theoretical and Experimental Vibrational Characterization of Biologically Active Nd(III) Complex
Molecules, 2021 The neodymium(III) complex of orotic acid (HOA) was synthesized and its structure determined by means of analytical and spectral analyses. Detailed vibrational analysis of HOA, sodium salt of HOA, and Nd(III)–OA systems based on both the calculated and ...
Irena Kostova +2 more
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Approbation of a Model of Fat Liver Disease Induced by Orotic Acid
Разработка и регистрация лекарственных средств, 2022 Introduction. For the treatment of non-alcoholic fatty liver disease (NAFLD), hepatoprotective drugs are actively used. The existing models of non-alcoholic fatty liver disease used to study the effectiveness of medicinal products are characterized by a ...
V. V. Kovanskov +5 more
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