Results 31 to 40 of about 80,486 (246)

Magnesium Sulfate versus Nitroglycerin in Controlled Hypotensive Anesthesia in Middle Ear Surgeries [PDF]

open access: yesInternational Journal of Medical Arts, 2020
Background: Controlled hypotension is required for middle ear surgeries to achieve a bloodless operative field and improve its quality, both magnesium sulfate and nitroglycerine used to produce deliberate hypotension.
Tawfik Noor El-Din   +3 more
doaj   +1 more source

ZW4864‐mediated inhibition of the β‐catenin/BCL9/BCL9L complex reveals therapeutic potential in bladder cancer

open access: yesMolecular Oncology, EarlyView.
BCL9 and BCL9L drive bladder cancer progression by enhancing β‐catenin signaling, promoting proliferation, migration, invasion, and organoid growth. Genetic depletion of BCL9(L) suppresses malignant phenotypes, while pharmacological disruption of the β‐catenin/BCL9(L) complex with ZW4864 inhibits canonical Wnt signaling and tumor‐associated cellular ...
Roland Kotolloshi   +11 more
wiley   +1 more source

Study on Optimization of Extracting Magnesium Sulfate from Acid-leaching Eluent of Serpentine by Solventing-out Crystallization

open access: yesKuangchan zonghe liyong, 2023
In order to make full use of China's non-metallic mineral resources containing magnesium, and improve the comprehensive recovery rate of magnesium in serpentine, a new process of enriching magnesium from serpentine leaching solution at normal temperature
Xiangyu Peng   +4 more
doaj   +1 more source

CEACAM1 participation in breast cancer progression

open access: yesMolecular Oncology, EarlyView.
In invasive breast cancer (BC), CEACAM1 shifts from an apical to a uniform membranous/cytoplasmic pattern, or is lost, as tumors dedifferentiate, inversely tracking the Ki‐67 proliferative index. In MCF‐7 cells, only CEACAM1‐4L suppresses proliferation, repressing cell cycle and growth factor genes.
Mykola Lyndin   +3 more
wiley   +1 more source

Effect of Maternal Body Mass Index on Serum Magnesium Level in Pregnant Women with Preeclampsia at Maharat Nakhon Ratchasima Hospital

open access: yesThai Journal of Obstetrics and Gynaecology, 2017
Objectives: To compare serum magnesium level in pregnant women with severe preeclampsia between normal body mass index (BMI) and high BMI after receiving magnesium sulfate at Maharat Nakhon Ratchasima Hospital.
Pemika Jaisamut, Siraya Kitiyodom
doaj   +1 more source

Identifying transcription factors controlling the basal expression of human MRP4 highlights a substantial role for Sp1

open access: yesFEBS Open Bio, EarlyView.
The MRP4 transporter exports several drugs and signaling molecules. Here, we identified key promoter elements regulating basal MRP4 expression. Using reporter assays, we defined a conserved region with essential Sp1 and contributory Ets sites, which controlled basal MRP4 expression.
Debora Singer   +7 more
wiley   +1 more source

The study of neuroprotective and anti-inflammatory effects of magnesium sulfate in rats following cerebral ischemia reperfusion injury

open access: yesKufa Journal for Veterinary Medical Sciences, 2014
Background and objective: Magnesium sulfate has neuroprotective effects and decrease overall neuronal firing. It is also decrease firing of excitable tissues outside the brain.
Ahmed MH Al-Mudhafar
doaj   +1 more source

Versatile vector tools for efficient protein screening across multiple expression systems

open access: yesFEBS Open Bio, EarlyView.
A unified vector toolkit enables rapid protein expression screening across E. coli, insect, and mammalian cells. A single primer pair amplifies the target gene, which is inserted into any vector via a standardized interface. This streamlined workflow eliminates repeated cloning steps, accelerating the identification of optimal expression conditions for
Zhimin Zhu   +5 more
wiley   +1 more source

Shortened Postpartum Magnesium Sulfate Treatment for Severe Preeclampsia

open access: yesThai Journal of Obstetrics and Gynaecology, 2010
Objectives:To compare the benefits and risks of shortened postpartum magnesium sulfate with traditional 24 hours postpartum magnesium sulfate for treatment of severe preeclampsia and evaluate reinitiation rate of magnesium sulfate and eclamptic seizure ...
Jiraphol Kumpalum   +1 more
doaj  

Cyclic azapeptide CD36 ligand attenuates cardiac injury and reduces long‐chain fatty acid accumulation after myocardial ischemia–reperfusion in mice

open access: yesFEBS Open Bio, EarlyView.
In a murine model of myocardial ischemia and reperfusion (MI/R), the CD36 azapeptide ligand MPE‐298 reduces cardiac injury and transiently lowers left ventricular long‐chain fatty acids (LCFAs) accumulation 3 h after reperfusion, accompanied by a decrease of oxidative stress and inflammation‐associated genes' expression in the heart and adipose tissue.
Jade Gauvin   +12 more
wiley   +1 more source

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