Differentiating Creatine and Phosphocreatine In Vivo Using 3 T 1H MR Spectroscopy
Magnetic Resonance in Medicine, Volume 95, Issue 4, Page 1896-1906, April 2026.ABSTRACT Purpose Validation and improvements to the proton MR spectroscopic measurement of creatine and phosphocreatine in vivo at 3 T. Methods Spectral simulations were used to evaluate and explore the mitigation of LCModel fitting bias due to lineshape, signal‐to‐noise (SNR) and non‐metabolite backgrounds with a focus on phosphocreatine and the ...
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