Results 61 to 70 of about 883,659 (269)
Molecular Oncology, EarlyView.Glioma cells mainly express the endothelin receptor EDNRB, while EDNRA is restricted to a perivascular tumor subpopulation. Endothelin signaling reduces glioma cell proliferation while promoting migration and a proneural‐to‐mesenchymal transition associated with poor prognosis. This pathway activates Ca2+, K+, ERK, and STAT3 signalings and is regulated
Donovan Pineau +36 more
wiley +1 more source
Feedforward equilibrium trajectory optimization with GSPulse
Nuclear FusionOne of the common tasks required for designing new plasma scenarios or evaluating capabilities of a tokamak is to design the desired equilibria using a Grad-Shafranov (GS) equilibrium solver.
J.T. Wai +7 more
doaj +1 more source
Ferroelectric Control of Magnetic Anisotropy
Nano Letters, 2011 We demonstrate unambiguous evidence of the electric field control of magnetic anisotropy in a wedge-shaped Co film of varying thickness. A copolymer ferroelectric of 70% vinylidene fluoride with 30% trifluoroethylene, P(VDF-TrFE) overlays the Co wedge, providing a large switchable electric field. As the ferroelectric polarization is switched from up to
Mardana, Abhijit +2 more
openaire +3 more sources
Controllability and control synthesis of underactuated magnetic microrobots
Automatica, 2023 The control of multiple magnetic microrobots is of particular interest for therapeutic applications. Yet the controllability of such a system is not straightforward since, on most of such systems designs, there is only a single control input per axis.
openaire +3 more sources
Interrogating the immune landscape of microsatellite stable RAS‐mutated colon cancer
Molecular Oncology, EarlyView.COLOSSUS project RAS‐mutated MSS colon cancer study explored transcriptomics and immune cell density by immunohistochemistry (IHC), Immunoscore (IS), ISIC/TuLIS scores, mutation counts, and detected different prevalences but similar microenvironment composition across immune markers with clinical relevance for future immunotherapy combination ...
Rodrigo Dienstmann +61 more
wiley +1 more source
High‐Efficiency Thermal Battery Regulated by Ultralow Magnetic Fields
Small ScienceControllable thermal storage has emerged as a central theme in advanced energy management, where external stimuli such as light, stress, and pressure can be exploited to precisely regulate heat release.
Lingli Li +5 more
doaj +1 more source
Molecular Oncology, EarlyView.We have established a humanized orthotopic patient‐derived xenograft (Hu‐oPDX) mouse model of high‐grade serous ovarian cancer (HGSOC) that recapitulates human tumor–immune interactions. Using combined anti‐PD‐L1/anti‐CD73 immunotherapy, we demonstrate the model's improved biological relevance and enhanced translational value for preclinical ...
Luka Tandaric +10 more
wiley +1 more source
Asymmetric magnetic dots: A way to control magnetic properties [PDF]
Journal of Applied Physics, 2011 We have used Monte Carlo simulations to investigate the magnetic properties of asymmetric dots as a function of their geometry. The asymmetry of round dots is produced by cutting off a fraction of the dot and is characterized by an asymmetry parameter α.
Vargas, N. M. +6 more
openaire +11 more sources
CCDC80 suppresses high‐grade serous ovarian cancer migration via negative regulation of B7‐H3
Molecular Oncology, EarlyView.PAX8 is a lineage‐specific master regulator of transcription in high‐grade serous ovarian cancer (HGSC) progression. We show for the first time that PAX8 facilitates proliferation and metastasis by repressing the cell autonomous tumor suppressor CCDC80 and inducing B7‐H3 expression.
Aya Saleh +12 more
wiley +1 more source
Magnetically Guided Microcatheter for Targeted Injection of Magnetic Particle Swarms
Advanced ScienceThe initial delivery of small‐scale magnetic devices such as microrobots is a key, but often overlooked, aspect for their use in clinical applications. The deployment of these devices within the dynamic environment of the human body presents significant ...
Harun Torlakcik +15 more
doaj +1 more source