Results 201 to 210 of about 3,961,025 (235)

Targeting CD300a Signaling With a Phosphatidylserine‐Presenting Hydrogel Rescues Macrophage Dysfunction and Accelerates Diabetic Wound Healing

Advanced Healthcare Materials, EarlyView.
Schematic illustration of the proposed mechanism: PEG/RGD‐PSLs mimic apoptotic cells to engage PS receptors (notably CD300a), transducing an inhibitory signal that suppresses the MyD88/NF‐κB pathway, leading to global anti‐inflammatory and pro‐reparative effects.
Lele Wu, Xuetong Hao, Yang Zou, Xinglin Chen, Junyan Kong, Chunning Gu, Wenjie Ma, Zhongjun Yang, Huifen Liu, Mengmeng Liu, Xin Tong   +10 more
wiley   +1 more source

PLL‐g‐HPA Hydrogel Microneedles Loaded With Rhoifolin Target Macrophages to Alleviate Fibroblast Senescence for Diabetic Wound Healing

Advanced Healthcare Materials, EarlyView.
Diabetic wound healing is hindered by a pathological crosstalk wherein elevated IL‐11 induces M1 macrophage polarization, leading to IL‐1β/IL‐6 release and subsequent fibroblast senescence via RAS/p38MAPK/p53/E2F1 signaling. Here, we develop a Gel@M‐Rho microneedle patch that delivers rhoifolin‐loaded, macrophage membrane‐coated nanoparticles to target
Jiewen Liao, Lin Gan, Li Lu, Lizhi Ouyang, Yuan Xiong, Fawwaz Al‐Smadi, Guandong Dai, Mohammad‐Ali Shahbazi, Bobin Mi, Mengfei Liu, Guohui Liu   +10 more
wiley   +1 more source

An Engineered Biomimetic Nanoreactor With Cascade Functions for Targeted and Combinatorial Therapy of Ischemic Stroke

Advanced Healthcare Materials, EarlyView.
Preparation of RVG‐modified erythrocyte membrane‐coated HMPB nanocarriers loaded with L‐arginine and NBP (RM@HPAN) and its neuroprotective mechanism. After intravenous injection, RM@HPAN achieves prolonged circulation, RVG‐29‐mediated BBB penetration, and ischemic accumulation.
Shaofa Li, Ying Wu, Huimin Wei, Jinyong Teng, Zaizhi Yang, Jufang Chen, Bao Liao, Xiaoqin Huang, Lanqing Meng, Tong Li   +9 more
wiley   +1 more source

Chemical Strategies for Multistimuli Responsive Dynamic Covalent Materials in Regenerative Medicine

Advanced Healthcare Materials, EarlyView.
Multistimuli responsive dynamic covalent materials integrate reversible chemistry with the complex chemical, mechanical, and biochemical cues of regenerative environments. This review highlights chemical strategies based on orthogonal dynamic bonds, multicomponent networks, and hierarchical architectures to regulate mechanics, degradation, and ...
Saurabh Joshi, Matthew B. Baker, Dominik Schauenburg   +2 more
wiley   +1 more source

Influence of Shell Thickness on the Colloidal Stability of Magnetic Core-Shell Particle Suspensions. [PDF]

Front Chem, 2018
Neville F, Moreno-Atanasio R.
europepmc   +1 more source

Advances in 3D Bioprinting for Breast Cancer Modeling: Tumor Microenvironment, Metastasis, and Drug Screening

Advanced Healthcare Materials, EarlyView.
Three‐dimensional bioprinting transforms breast cancer modeling from simple constructs into spatially organized, multicellular, perfused, and patient‐derived platforms. This review shows how bioinks, cellular composition, architecture, and flow govern tumor behavior and drug response, while revealing why complexity alone is insufficient without ...
Mustafa Nakipoglu, Mahboobeh Mahmoodi, Ehsanul Hoque Apu, Fahimeh Shahabipour, Sibel Emir Diltemiz, Sanjib Saha, Halima Alem, Nureddin Ashammakhi   +7 more
wiley   +1 more source

Novel magnetic core-shell nanoparticles for the removal of polychlorinated biphenyls from contaminated water sources. [PDF]

Mater Chem Phys, 2019
Gutierrez AM, Bhandari R, Weng J, Stromberg A, Dziubla TD, Hilt JZ.   +5 more
europepmc   +1 more source

NeuroVisio SyncPatch: A Skin‐Conformal Multimodal EMG–Motion Sensing Platform for Quantitative Neuromuscular Rehabilitation and Performance Monitoring

Advanced Healthcare Materials, EarlyView.
NeuroVisio SyncPatch integrates skin‐conformal electromyography (EMG) electrodes with camera‐tracked markers to jointly assess muscle activity and three‐dimensional knee kinematics during rehabilitation. Parallel feedback pathways provide real‐time kinematic guidance during movement and post‐trial neuromuscular feedback.
Bohyung Choi, Yoo‐Jin Jun, Heewon Choee, Kun‐Do Lee, Heesoo Kim, Yu Seok Hwang, Choong Yeon Kim, Seongok Chae, Juhyun Lee, Minkyu Je, Jae‐Woong Jeong, Hyung‐Soon Park   +11 more
wiley   +1 more source

Microfluidic Engineering of Microgels: A Review of Emerging Technologies, Materials, Fabrication Strategies, and Applications

Advanced Healthcare Materials, EarlyView.
Recent advances in microfluidic technologies for microgel fabrication are critically reviewed, highlighting the capabilities and limitations of major microfluidic platforms and discussing how platform design, material selection, and crosslinking strategies influence microgel architecture and functionality. Current challenges and future opportunities in
Afshin Abrishamkar, Laura Neely, Cynthia Pham, Nada Ibrahim, Alexis Larios‐Cervantes, Ben A. Kertesz, Todd Hoare   +6 more
wiley   +1 more source

Protein‐Polymer Dynamic Hydrogels Utilizing Native Ligand Binding for Injectable Therapeutic Delivery and 3D Printing

Advanced Healthcare Materials, EarlyView.
Dynamic nanocolloidal hydrogels were synthesized via the co‐assembly of ligand‐modified spheroidal hyperbranched poly(glycerol) (HPG) and soluble albumin nanoparticles (SANs). Co‐assembly occurred through self‐association of the HPG, as well as its interaction with SANs via native ligand binding.
S. Cem Millik, Yonghui Wang, Kefan Song, Jessica M. Snyder, LeAnn Le, Lauren G. Brown, Shanny Hsuan Kuo, Ashleigh B. Theberge, Suzie H. Pun, Alshakim Nelson   +9 more
wiley   +1 more source