Results 61 to 70 of about 1,018,221 (292)
Intein‐based modular chimeric antigen receptor platform for specific CD19/CD20 co‐targeting
Molecular Oncology, EarlyView.CARtein is a modular CAR platform that uses split inteins to splice antigen‐recognition modules onto a universal signaling backbone, enabling precise, scarless assembly without re‐engineering signaling domains. Deployed here against CD19 and CD20 in B‐cell malignancies, the design supports flexible multi‐antigen targeting to boost T‐cell activation and
Pablo Gonzalez‐Garcia +9 more
wiley +1 more source
Research on application of magnetic cores based on impedance characteristic
Dianzi Jishu Yingyong, 2019 According to the basic characteristics of inductive components and the mechanism of suppressing electromagnetic interference caused by the magnetic cores, the influence on the impedance of magnetic cores of the material type，core size and the number of ...
Wang Hui +3 more
doaj +1 more source
Nanomaterials, 2020 Iron oxide nanoparticles are the basic components of the most promising magnetoresponsive nanoparticle systems for medical (diagnosis and therapy) and bio-related applications.
Theodora Krasia-Christoforou +5 more
doaj +1 more source
, 2013 The energy of magnetic vortex core and its equilibrium radius in thin circular cylinder were first presented by N.A. Usov and S.E. Peschany in 1994. Yet, the magnetostatic function, entering the energy expression, is hard to evaluate and approximate.
Aharoni +18 more
core +1 more source
Dual targeting of RET and SRC synergizes in RET fusion‐positive cancer cells
Molecular Oncology, EarlyView.Despite the strong activity of selective RET tyrosine kinase inhibitors (TKIs), resistance of RET fusion‐positive (RET+) lung cancer and thyroid cancer frequently occurs and is mainly driven by RET‐independent bypass mechanisms. Son et al. show that SRC TKIs significantly inhibit PAK and AKT survival signaling and enhance the efficacy of RET TKIs in ...
Juhyeon Son +13 more
wiley +1 more source
Calculation of Reactances for Ring Windings to Toroidal Inductors of Hybrid Induction Machine
Advances in Electrical and Computer Engineering, 2009 The linear induction motors of hybrid structure have a series of particularities and their most precise estimation of practical flows and outlets has a high level of complexity, especially due to the different form of inductor.
POPA, C. +3 more
doaj +1 more source
Core-Loss Analysis of Linear Magnetic Gears Using the Analytical Method
Energies, 2021 In this study, analysis of core-loss occurring in the magnetic flux modulation core of a linear magnetic gear and the core of each mover is presented, using an analytical method.
Jeong-In Lee +5 more
doaj +1 more source
Extracting scaling laws from numerical dynamo models
, 2013 Earth's magnetic field is generated by processes in the electrically conducting, liquid outer core, subsumed under the term `geodynamo'. In the last decades, great effort has been put into the numerical simulation of core dynamics following from the ...
Jackson, A., Stelzer, Z.
core +1 more source
ATF4‐mediated stress response as a therapeutic vulnerability in chordoma
Molecular Oncology, EarlyView.We screened 5 chordoma cell lines against 100+ inhibitors of epigenetic and metabolic pathways and kinases and identified halofuginone, a tRNA synthetase inhibitor. Mechanistically halofuginone induces an integrated stress response, with eIF2alpha phosphorylation, activation of ATF4 and its target genes CHOP, ASNS, INHBE leading to cell death ...
Lucia Cottone +11 more
wiley +1 more source
Magnetic core current steering commutator Patent [PDF]
, 1970 Describing magnetic core current switching device for steering bipolar current pulses to memory ...
Zottarelli, L. J.
core +1 more source