Results 61 to 70 of about 1,019,438 (296)
ATF4‐mediated stress response as a therapeutic vulnerability in chordoma
Molecular Oncology, EarlyView.We screened 5 chordoma cell lines against 100+ inhibitors of epigenetic and metabolic pathways and kinases and identified halofuginone, a tRNA synthetase inhibitor. Mechanistically halofuginone induces an integrated stress response, with eIF2alpha phosphorylation, activation of ATF4 and its target genes CHOP, ASNS, INHBE leading to cell death ...
Lucia Cottone +11 more
wiley +1 more source
Research on application of magnetic cores based on impedance characteristic
Dianzi Jishu Yingyong, 2019 According to the basic characteristics of inductive components and the mechanism of suppressing electromagnetic interference caused by the magnetic cores, the influence on the impedance of magnetic cores of the material type，core size and the number of ...
Wang Hui +3 more
doaj +1 more source
Nanomaterials, 2020 Iron oxide nanoparticles are the basic components of the most promising magnetoresponsive nanoparticle systems for medical (diagnosis and therapy) and bio-related applications.
Theodora Krasia-Christoforou +5 more
doaj +1 more source
, 2010 We made deep NIR imaging polarimetry toward the Serpens cloud core. The polarization vector maps enable us to newly detect 24 small IR reflection nebulae with YSOs.
Allen +54 more
core +1 more source
Molecular Oncology, EarlyView.This work identified serum proteins associated with pancreatic epithelial neoplasms (PanINs) and early‐stage PDAC. Proteomics screens assessed genetically engineered mice with abundant PanINs, KPC mice (Lox‐STOP‐Lox‐KrasG12D/+ Lox‐STOP‐Lox‐Trp53R172H/+ Pdx1‐Cre) before PDAC development and also early‐stage PDAC patients (n = 31), compared to benign ...
Hannah Mearns +10 more
wiley +1 more source
Calculation of Reactances for Ring Windings to Toroidal Inductors of Hybrid Induction Machine
Advances in Electrical and Computer Engineering, 2009 The linear induction motors of hybrid structure have a series of particularities and their most precise estimation of practical flows and outlets has a high level of complexity, especially due to the different form of inductor.
POPA, C. +3 more
doaj +1 more source
Core-Loss Analysis of Linear Magnetic Gears Using the Analytical Method
Energies, 2021 In this study, analysis of core-loss occurring in the magnetic flux modulation core of a linear magnetic gear and the core of each mover is presented, using an analytical method.
Jeong-In Lee +5 more
doaj +1 more source
Extracting scaling laws from numerical dynamo models
, 2013 Earth's magnetic field is generated by processes in the electrically conducting, liquid outer core, subsumed under the term `geodynamo'. In the last decades, great effort has been put into the numerical simulation of core dynamics following from the ...
Jackson, A., Stelzer, Z.
core +1 more source
RIPK4 function interferes with melanoma cell adhesion and metastasis
Molecular Oncology, EarlyView.RIPK4 promotes melanoma growth and spread. RIPK4 levels increase as skin lesions progress to melanoma. CRISPR/Cas9‐mediated deletion of RIPK4 causes melanoma cells to form less compact spheroids, reduces their migratory and invasive abilities and limits tumour growth and dissemination in mouse models.
Norbert Wronski +9 more
wiley +1 more source
Testing Magnetic Field Models for the Class 0 Protostar L1527
, 2014 For the Class 0 protostar, L1527, we compare 131 polarization vectors from SCUPOL/JCMT, SHARP/CSO and TADPOL/CARMA observations with the corresponding model polarization vectors of four ideal-MHD, non-turbulent, cloud core collapse models.
Chapman, N. L. +12 more
core +1 more source